Cell And Gene Articles, App Notes, Case Studies, & White Papers

  1. A Scalable Manufacturing Platform For The Purification Of Stem Cell Derived Exosomes 5/16/2025

    EV production scale increases require paired robust, scalable, and cost-effective downstream processes. Process parameters can be tailored for therapeutic exosome programs and allow for maximum exosome recovery.

  2. How To Evaluate And Compare Real-Time PCR Reactions 10/30/2024

    Learn about the key factors that influence qPCR reaction performance and provides guidelines for evaluating and comparing reactions run under varying conditions to ensure reliable data interpretation.

  3. Aggregation In Antibody-Drug Conjugates: Causes And Mitigation 9/1/2025

    Discover how early intervention in ADC development can streamline clinical progress, ensure stability and safety, and accelerate commercialization with expert guidance.

  4. A Smartphone Based Biomarker For The Estimation Of Unipolar Depression Severity 3/28/2025

    The study investigates the potential of using smartphones and wearables to create objective biomarkers for mood disorders, specifically focusing on unipolar depression.

  5. Optimizing And Intensifying ADC Aggregate Removal With A DoE Approach 11/29/2023

    This study explores the feasibility of using single-use chromatography membrane technology as an alternative to resin-based chromatography in an ADC process.

  6. Standardizing Cryopreservation For Cell Therapy Supply Chains 6/3/2025

    Explore how a standardized cryopreservation process is transforming leukapheresis handling by reducing risk and improving quality across the cell therapy supply chain.

  7. Analytical Method Release And Stability Platform For RNA Drug Substance 3/14/2025

    We offer comprehensive analytical support across the R&D space, including method development, validation, process characterization, in-process testing, process validation, and GMP release testing.

  8. Mobile Gowning Cleanroom, Built To Meet ISO 7 Requirements 6/19/2024

    Uncover how Germfree designed and installed a mobile cGMP cleanroom on a 53′ tractor-trailer chassis to provide a flexible and efficient cleanroom solution tailored to the company’s needs.

  9. NDA Success Strategy: Using Non-US Clinical Data In An NDA Submission 8/12/2025

    A sponsor acquiring a therapeutic asset from an overseas company sought assistance when including foreign clinical trial dat,a generated outside a U.S. IND, in a New Drug Application (NDA).

  10. Accelerating The Development And Optimization Of Cell Culture Media 10/18/2024

    Here, we outline the use of a microbioreactor for the rapid screening and optimization of media formulations for perfusion processes, and its role in predicting the performance of larger-scale bioreactors.