Cell And Gene Articles, App Notes, Case Studies, & White Papers

  1. Development Of LNP Formulations Using The KNAUER NanoScaler 12/6/2024

    Lipid nanoparticles (LNPs) offer a robust solution for nucleic acids. The NanoScaler system optimizes this technology, enabling scalable and reproducible LNP formulations for diverse applications.

  2. A Checklist For Efficient And Reliable Gene Therapy Manufacturing 6/3/2024

    Gain insight into how to design and execute an efficient upstream AAV production process, and follow the checklist within to ensure all appropriate factors are considered at each phase of drug development.

  3. Generation Of Stable CHO Cell Lines For Protein Production 3/22/2024

    By following the five steps of a specialized protocol, exceptional yields and stable cell lines can be achieved in CHO cells using antibiotic selection.

  4. Coordinating Global Capabilities To Support A Gene Therapy Targeting A Rare Neurodegenerative Disorder 1/14/2025

    Advance your gene therapy program with expert support for IND submission, including GLP toxicology, biodistribution studies, and tailored CMC services.

  5. Replicate Bioscience And Cytiva Collaborate To Deliver srRNA-LNP Vaccines 3/24/2025

    Discover how self-replicating RNA (srRNA) can revolutionize vaccine development with sustained protein expression, lower doses, and fewer side effects to advance next-gen RNA therapeutics.

  6. Extractables In Single-Use Systems Used In ADC Manufacturing 9/23/2024

    To address concerns about using organic solvents in the ADC process, extractables studies were conducted on a disposable chromatography column housing and two different disposable flow paths.

  7. Use Of Roche Recombinant Trypsin For Cell Culture Applications 8/11/2025

    Review the use of a recombinant trypsin in cell culture applications, such as the detachment of adherent cells, in particular with cell lines used in vaccine production.

  8. Global Regulatory Excellence During The Clinical Development Lifecycle 5/8/2024

    Navigating the intricate global regulatory path is crucial for clinical development success. See how expert-backed support has consistently propelled sponsors toward regulatory excellence.

  9. A Streamlined Biopharmaceutical Isolator Solution 6/19/2024

    This custom-designed, eight-foot isolator helped a client meet their decontamination needs, maintaining ISO-5 sterile conditions while decreasing turn-around time for filling small batches.

  10. Streamlining Phase I/II Oncology Trials: A Global CRO Partnership 3/17/2025

    Through strategic planning, adaptive trial execution, and proactive collaboration, TFS successfully navigated the complexities of this early-phase oncology study.