Cell And Gene Articles, App Notes, Case Studies, & White Papers

31. Rapid Startup Phase 1 Cardiomyopathy CRISPR Gene Therapy 9/25/2025

    Hereditary transthyretin amyloidosis (ATTRv) is very rare, prompting a Phase 1 trial of in vivo CRISPR/Cas9 gene editing to reduce mutant protein and stop cardiomyopathy progression.

32. Rapidly Assess Drug Response In 2D And 3D Breast Cancer Model Systems 4/4/2025

    For years, 2D cell cultures have been crucial in drug discovery. Explore how 3D cultures offer more biologically relevant models today that enhance cancer research and drug efficacy assessments.

33. Selecting A Platform Filter For High Concentration mAbs 4/9/2025

    Read more about how Fujifilm Diosynth Biotechnologies evaluated a prime filter with challenging simulant solutions and how the experimental data confirmed superior performance, which demonstrated twice the throughput.

34. A Transient Cell Line To Produce rAAV With Low-Level hcDNA Encapsidation 1/15/2025

    Discover the ability of a novel HEK293 suspension cell line for efficient and scalable rAAV production across various serotypes with low encapsidated host cell DNA levels.

35. Jaw Crimping vs. Rotary Crimping: Enhancing Aseptic Assurance 6/12/2025

    Beyond a simple mechanical step, crimping is a critical control point. We examine how advanced rotary technology provides superior seal quality, particulate control, and data-driven compliance assurance.

36. Background-Free Analysis Of Mouse TILs 3/28/2025

    Syngeneic mouse tumor models are crucial for immunotherapy research, but variability in TILs and nonspecific binding complicate analysis. Discover how blocking reagents help but make the process more labor-intensive.

37. Evaluating CAR T-Cell Therapy Vascular Recruitment, Trafficking, And Killing 4/24/2024

    Learn about a more human-relevant platform that enables researchers to assess the trafficking and killing efficiency of immunotherapy as well as the proof-of-concept of immuno-oncology co-therapy.

38. Virus Retention Performance Under Diverse Processing Conditions 11/14/2025

    Virus filtration is robust across a wide range of process parameters, including high protein concentration and flow decay. Discover how retention relies on size exclusion to simplify risk assessment.

39. A Better Immune Response To Vaccination: Using Lymphoid Follicle Organ-Chips 4/9/2024

    Discover a first-of-its-kind human LF-Chip containing B, T, plasma and antigen-presenting cells to test functional immunization responses to vaccines and adjuvants in vitro.

40. Benchmarking Filtration Performance Of TFF Cassettes 5/30/2025

    Optimize your protein purification workflow with tangential flow filtration by comparing membrane performance and exploring how protein concentration impacts flux and MWCO selection in lab-scale systems.