CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• The Proven Supplement For CAR-T Solid Tumor Cytotoxicity

  Optimize cell culture for solid tumor research. Replacing traditional serum can significantly enhance CAR-T cytotoxicity, improve consistency, and streamline the path to GMP-ready workflows.

• Advancing Drug Safety And Improving R&D Productivity With The Liver-Chip S1

  Explore how the Emulate Liver-Chip S1 revolutionizes predictive toxicology by mimicking human liver biology, achieving superior sensitivity and specificity.

• Modeling Inflammation-Specific Immune Cell Recruitment

  Traditional models for studying inflammatory bowel disease (IBD) often fall short. See how the Colon Intestine-Chip was used to model the progression of IBD driven by immune cells more completely.

• Stabilization Of RNA-Loaded Lipid Nanoparticles By Lyophilization

  Discover how lyophilization enhances RNA-based therapeutics by enabling storage at higher temperatures, which simplifies cold-chain logistics while preserving nanoparticle integrity and biological activity.

• Revolutionizing Viral Infectious Disease Research And Drug Discovery

  Learn how Organ-Chips are being used to rapidly identify promising treatments, investigate virus evolution, and analyze how mechanical forces influence the innate immune response to viral infections.

• Phase 1 Clinical Trial Designs And Strategies

  With tailored guidance, sponsors can align their modern model-based and model-assisted design choices to program goals, accelerating progress while safeguarding patients.

• Automation And Digital Solutions Can Help You Reach Your mRNA Manufacturing And Sustainability Goals

  Explore how digital solutions help streamline mRNA manufacturing by reducing costs, improving efficiency, and supporting sustainability by creating paperless processes for emerging therapeutics.

• Virus Reduction And Impurity Removal

  Examine a DOE-based study that reveals how buffer conditions impact virus and impurity clearance using a mixed-mode resin, as well as gain practical guidance for optimizing downstream purification.

• Media Exchange In iPSC Cell Expansion And Differentiation: A Comparative Study

  Low-shear, closed-system media exchange in iPSC differentiation is vital for scalability. This study compares automated centrifugation to gravity sedimentation, showing equivalent or superior differentiation outcomes.

• Integrated Upstream And Downstream Strategies For Robust mAb Manufacturing

  Process robust mAb production requires understanding scale dependent cell environments, leveraging predictive models, and pursuing data driven control to minimize variability, optimize quality, and ensure reliable technology transfer across biomanufacturing scales.