CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Automated Enrichment Of Human CD34+ Cells

  Explore an automated approach to CD34+ cell enrichment that combines scalable processing and high-purity cell recovery, offering insight into performance metrics and practical considerations.

• Finding An Optimal Harvest Solution By Considering Both Cost And Sustainability

  Optimize your bioprocessing harvest with single-use centrifugation. Reduce costs, waste, and space needs compared to traditional depth filtration methods.

• A Novel Approach To Improving AAV Titers

  As demand for AAV-based therapies rises, optimizing production processes is essential. By utilizing existing technologies, tailored platforms, and optimized formulations, titers and productivity can be enhanced.

• Collaborative Variability Reduction In Cell Culture Media

  Variability reduction programs improve biomanufacturing by controlling raw‑material complexity, optimizing critical attributes, and boosting productivity through data‑driven partnerships.

• Navigating Commercial Logistics For CGTs: A Roadmap To Scalable, Patient-Centered Success

  The commercialization of cell and gene therapies requires a precise and resilient logistics model that can adapt to rapid demand and global expansion while maintaining a patient-first approach.

• Guiding Principles For Process Development And IND Readiness

  Observe how a milestone-driven risk management strategy streamlines cell therapy development, reduces uncertainty, and aligns early decisions with long-term commercialization and regulatory success.

• The Case For Non-Viral Circular Single-Stranded HDR Donors

  Enable efficient, low-toxicity genome editing without viral vectors. This cell-free circular ssDNA platform preserves stem cell fitness while supporting scalable manufacturing.

• Automation Of iPSC Culture, Passaging, And Expansion

  Find out how iPSC-derived models enable researchers to generate diverse cell types and tissues as well as how automation reduces the labor-intensive culturing process with AI-powered decision-making.

• Accelerate LNP Manufacturing With Automated Process Development

  Manual LNP formulation introduces process variability that threatens particle quality and yield. As programs scale toward clinical production, maintaining strict control over CQAs becomes essential.

• Ensuring Product Safety And Purity With Mycoplasma And Sterility Testing

  Discover how the Applied Biosystems™ MycoSEQ™ Plus system and Applied Biosystems™ SteriSEQ™ Rapid Sterility Testing System can help accelerate your cell therapy manufacturing process.