CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Rapidly Assess Drug Response In 2D And 3D Breast Cancer Model Systems

  For years, 2D cell cultures have been crucial in drug discovery. Explore how 3D cultures offer more biologically relevant models today that enhance cancer research and drug efficacy assessments.

• Media Exchange In iPSC Cell Expansion And Differentiation: A Comparative Study

  Low-shear, closed-system media exchange in iPSC differentiation is vital for scalability. This study compares automated centrifugation to gravity sedimentation, showing equivalent or superior differentiation outcomes.

• Expert Insights In Navigating CGT's Complex Supply Chain

  Examine insights shared during Cencora's ThinkLive Cell and Gene Therapy Summit 2024 that shed light on the challenges and opportunities in navigating the complexities of the cell and gene supply chain.

• Accelerating Clinical Data Review With Traceable Workflows

  Clinical data review needs centralized access and traceable workflows. Leveraging AI-automation and real-time collaboration drives faster, better-informed decisions and reduced compliance risk.

• High-Performance Extraction And Quantitation Of Host-Cell Residual DNA

  This study presents a high-efficiency method for extracting and quantifying residual DNA from host cells using a semi-automated, high-throughput workflow.

• Innovating The mAb Characterization Process

  Understanding the characteristics of a molecule's "personality" is crucial for optimizing development and manufacturing. Learn how to overcome the challenges in the characterization process.

• Ensuring cGMP Compliance In Cell And Gene Therapy Manufacturing

  Discover how adhering to strict GMP guidelines and advanced equipment design ensures that complex, sterile cell and gene therapies are safely and effectively delivered.

• TFF Cassettes With 100 kDa Membranes For RNA And LNP Applications

  This study showcases the performance of regenerated cellulose flat sheet membranes with a 100 kDa molecular weight cutoff for UF/DF of RNA molecules by TFF.

• The Value Of Peptones For Cost-Effective Vaccine Manufacturing

  Peptones offer a strategic solution to key biomanufacturing challenges by enhancing cell culture performance, improving yields, and reducing production costs.

• A Beginner's Guide To Mesenchymal Stem Cell Culture

  Gain a foundational understanding of the process for culturing mesenchymal stem cells in stirred-tank bioreactors and learn about the key parameters for successful scale-up.