CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• The Importance Of Quality In Raw Material Selection

  Learn how to select high-quality raw materials for cell-based manufacturing in this exploration of the criticality of raw materials, from preclinical development to commercialization. 

• Enhanced Development Of Virus-Specific Hybridomas

  Double-stranded DNA viruses cause various human diseases, which complicates diagnosis due to antigen conservation. Explore a cell line that produces specific monoclonal antibodies to aid biotherapeutics development.

• Modern Lentiviral Platforms For Scalable Cell Therapy

  A new platform approach streamlines lentiviral vector design and manufacturing, boosting yield, lowering costs, and accelerating access to gene‑modified cell therapies worldwide.

• Enabling Accelerated Raman Model Calibration For Real-Time Monitoring

  Raman spectroscopy is a key component of a PAT strategy. Evaluate an innovative workflow designed to streamline the integration of an in-line Raman analyzer for bioreactor applications.

• Building A Scalable Digital Foundation To Support CGT Manufacturing

  Explore how digital systems strengthen CGT manufacturing by improving traceability and managing batch‑of‑one, as well as essential steps toward scalable, integrated operations.

• Performance Of A Customizable DMSO-Free Cryopreservation Media Formulation

  Cryopreservation enables cell therapy by storing cells long-term. A DMSO-free formula preserves cell viability and health, minimizing toxicities linked with traditional cryoprotectants.

• The Proven, Practical Gateway To Upstream Process Intensification

  N-1 perfusion enables higher inoculum densities, faster production, and reduced costs without altering fed-batch processes. Explore a practical path to intensification for biologics manufacturers.

• How Patient-Centric Approaches Are Shaping The Future Of CGT

  Emily Whitehead’s CAR-T cell therapy journey highlights the power of patient engagement in cell and gene therapies. Discover how her story and advocacy drive a patient-centric approach in innovative treatments.

• Optimizing Performance For De-Risked Lentiviral Vector Production

  Discover a de-risked, reproducible, and scalable platform for efficient GMP manufacturing of lentiviral vectors that maximizes titers and enriches recovery through upstream and downstream optimization.

• AAV Viral Titering Using Nanoplate-Based Digital PCR

  Examine how nanoplate-based digital PCR streamlines AAV titering, providing faster results and greater accuracy, advancing gene therapy development from the lab to the clinic.