CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Delivering A Registrational GI Trial Through Ongoing Protocol Shifts

  A biotech developing bispecific antibodies partnered with a flexible CRO to launch its first U.S. GI oncology trial, requiring strategic insight and full-service clinical support.

• Overcoming Analytical Bottlenecks In Oligonucleotide Drug Development With Automation

  Growing oligonucleotide complexity is straining traditional analytical workflows. See how automated LC‑UV‑MS processing offers a scalable way to boost throughput and reduce manual effort.

• Optimization And Scale-Up Of A Plasmid DNA Production Process

  Optimizing pDNA production in E. coli requires strategic media selection and scale-up planning. Explore a study that identifies ideal conditions for high-yield manufacturing.

• Analysis Of Partial Capsids Using Empty-Full Capsid Kit

  Discover how to assess AAV genome integrity beyond ITR-2 using an extended ddPCR method for precise quantification of empty and full capsids with various genomic targets.

• A Journey To Produce MSC-Derived Cell Therapies From Isolation To Large-Scale

  Drive successful MSC therapy development by optimizing isolation methods, surface chemistry, and closed-system expansion technologies to ensure cellular stability and commercial scalability.

• Advances In Analytical Method Selection And Technology Transfer

  Successful analytical method transfer is crucial for product quality and regulatory compliance. Learn best practices for tech transfer, including how gap assessments mitigate common risks and streamline bioprocessing.

• Digitized Solutions To Increase Visibility And Streamline Communication Between A PSP And Manufacturer

  When email-based escalation management creates compliance and visibility gaps, a centralized digital solution helps manufacturer and PSP teams act faster and with greater accountability.

• The Proven Supplement For CAR-T Solid Tumor Cytotoxicity

  Optimize cell culture for solid tumor research. Replacing traditional serum can significantly enhance CAR-T cytotoxicity, improve consistency, and streamline the path to GMP-ready workflows.

• Evaluate The Effects Of A Xeno-Free Serum Replacement Media Supplementation

  This study compares the impact of a specific Human Growth Factor Concentrate (hGFC) and fetal bovine serum (FBS) on the growth, expansion, and viability of MSCs.

• The Unique Challenges Of The Cell & Gene Therapy Supply Chain

  Cell and gene therapies present unique logistical challenges for the supply chain, requiring careful consideration of factors like shelf life, packaging, temperature, and chain of custody.