CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Selecting A Reversed-Phase Column For The Peptide Mapping Analysis Of A Biotherapeutic Protein

  In this study we review reversed-phase (RP) column selection considerations for peptide mapping applied to the routine characterization and analysis of biotherapeutic proteins.

• Combining VIPS And ATUM To Accelerate Cell Line Manufacturing

  Scientists are constantly striving to develop the highest producing clones and to do it faster. We now demonstrate how this can be achieved by using only a handful of cloning plates.

• How To Develop A Cell Therapy Manufacturing Roadmap

  A good manufacturing roadmap provides flexible guidelines to advance automation. It’s a living document and will be refined many times as manufacturing needs and processes evolve. The key is mapping out the entire process and developing a clear understanding of what needs to be done and when. Here are the key questions to ask when building a manufacturing roadmap.

• Closed Manufacturing System For Autologous Cell Therapy Production

  Complete manufacturing system delivered technology innovation, novel automation solutions, and substantial IP in the cell therapy manufacturing automation domain.

• 5 Advantages Of A Single-Use Manifold Configurator

  The interface between systems and bags or bottles often proves a bottleneck. Learn how to adapt single-use filling assemblies to meet changing needs in the production and filling process.

• High Efficiency Single Cell Cloning Of iPSCs Using Combination Of MatriClone And VIPS

  Review an effective turnkey solution for generating significantly more viable iPSC clones per plate along with image documentation for their clonal derivation.

• How to Select the Right Integrity Test Instrument

  Filter integrity testing, from its origins in the 1970s, has undergone significant changes over the last 40 years as industry needs, and the evolution of regulatory expectations have pushed boundaries to reduce risk and increase patient safety. This guide will help you select the right integrity test instrument, including criteria that will allow accurate filter integrity testing that is fully compliant to current regulations.

• Do I Need To Validate? How To Make An Informed Decision In 4 Steps

  Nobody ever said software validation is easy. Validation is twice as tough if you are plagued by uncertainty and asking yourself: do I really need to validate? It’s a legitimate question. In this paper we walk you through the necessary thought process to make an informed decision.

• Differentiation Of Leucine And Isoleucine Using Electron Activated Dissociation (EAD)

  We demonstrate the combination of routine characterization and elucidation of challenging residues in one single analysis, without the need for sample specific optimization.

• Integrated Manufacturing: Chromatography Meets Predesigned DeltaV

  Cytiva’s pre-defined automation solution, Figurate, is now available as a turnkey solution by combining our industry-leading ÄKTA process chromatography system with the reliability of the DeltaV DCS platform.