CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

  • Transforming Cancer Research: Digital PCR Technology Plays Integral Role At Cancer Research Center
    Transforming Cancer Research: Digital PCR Technology Plays Integral Role At Cancer Research Center

    How  digital PCR technology is helping scientists in their quest to break through the current limits of nucleic acid detection and quantification.

  • Viral Clearance: The Basics On How To Conduct Effective Studies
    Viral Clearance: The Basics On How To Conduct Effective Studies

    Effective viral clearance studies remain one of the challenges facing manufacturers of biologics. These studies are an essential part of process validation and are critical to ensure drug safety. This article provides the basics of what you need to know when studying virus reduction of a chromatography step.

  • Cell & Gene Therapies: SUT Connection Lessons From Biotech
    Cell & Gene Therapies: SUT Connection Lessons From Biotech

    Single use connection technologies are expected to play a critical role in commercial manufacturing of cell and gene therapies. Learn about the types of connection technologies and selection considerations.

  • Is A Rapid Cooling Step Needed When Freezing Cells For Cryopreservation?
    Is A Rapid Cooling Step Needed When Freezing Cells For Cryopreservation?

    Successful cell cryopreservation requires a controlled cooling rate. Cooling too rapidly or too slowly will lead to a poorer outcome. This study shows comparable results when freezing cells with or without a rapid-cooling nucleation step.

  • Analysis Of Mixed Microbial Populations And Deep Immunotyping Of Peripheral Blood On The ZE5™ Cell Analyzer
    Analysis Of Mixed Microbial Populations And Deep Immunotyping Of Peripheral Blood On The ZE5™ Cell Analyzer

    With up to five lasers and 30 analysis parameters, the ZE5™ Cell Analyzer is well equipped for complex multiplex analysis of cells. It is able to successfully perform large panel immunophenotyping and can also distinguish a wide range of bead sizes and mixed microbial populations.

  • Comparing Continuous And Batch Processing In Downstream Purification
    Comparing Continuous And Batch Processing In Downstream Purification

    Current state-of-the-art continuous manufacturing technologies are being developed and implemented to manufacture a wide variety of products including monoclonal antibodies, recombinant proteins, and other biological modalities. Though upstream fed batch and perfusion bioreactors unit processes are relatively mature, downstream process unit operations are less mature. In this case study, Catalent compared the productivity of purifications running in batch versus continuous mode.

  • Chill Out: Harnessing New Freezing Technology To Help Deliver The Future Of Medicine
    Chill Out: Harnessing New Freezing Technology To Help Deliver The Future Of Medicine

    Digitally enabled cryogenic cold chain technology can now deliver the raw materials needed to manufacture cellular therapies

  • Virus Reduction Of An Affinity Capture Step - Viral Clearance For Protein A
    Virus Reduction Of An Affinity Capture Step - Viral Clearance For Protein A

    Evaluating how much a process step contributes to viral clearance is an essential part of process validation in order to be sure you are manufacturing safe drugs. Learn more about how HiScale 10/40, packed with MabSelect PrismA, is a reliable choice for the capture step in a virus clearance study.

  • Isolation Of Individual Cells For Single-Cell Analysis
    Isolation Of Individual Cells For Single-Cell Analysis

    A demonstration of a simple workflow to verify the reliability of the S3e Cell Sorter in sorting single cells.

  • Immunotherapy: The Next Frontier For Cancer
    Immunotherapy: The Next Frontier For Cancer

    Does the human body have the capability to heal itself? The idea of immunotherapy, harnessing the body’s own immune system to eradicate disease, has moved from the realm of possibility to something much more tangible. Interestingly, this promising therapy is not a new concept and has actually existed for more than 125 years, originating when William Coley, MD introduced the notion that the immune system could be useful in the treatment of cancer. He had observed that bone and soft tissue sarcoma patients experienced remission as a result of a concurrent bacterial infection and began to treat patients with heat-killed streptococcal organisms that he called Coley toxins. The toxins he administered to patients resulted in a 50% near-complete remission rate (Institute for Clinical Immuno-Oncology 2015).

More Articles, App Notes, Case Studies, & White Papers
erin-header4

CELL & GENE CONTENT COLLECTIONS

CG_CommercializationStrategiesEbook_300x200

 

As the cell and gene therapy landscape continues to mature, so too do the intricacies of commercialization. Inside the pages of this free collection of articles, you’ll find insightful data addressing the challenges critical for the sustainability of cell and gene therapy business models.

More Content Collections

CELL & GENE INDUSTRY EVENTS

Root Cause Analysis & CAPA Identification: A Step-by-Step Guide for Manufacturers September 24 - 24, 2019
1pm-2:30pm EDT, Online Training
Smarter Development Of Chromatography Processes September 24, 2019
Time: 11:00 AM Eastern Daylight Time. Duration: 1 hour
Stability Programs – Key Factors in Meeting FDA/ICH Expectations September 26 - 26, 2019
1pm-2:30pm EDT, Online Training
Sterility Failure Investigations – A Step-by-Step Process for Success September 30 - 30, 2019
1pm-2:30pm EDT, Online Training
More Industry Events