Engineered oncolytic viruses are emerging as a promising way to target tumors, deliver immune-stimulating payloads, and improve treatment of metastatic cancer.
- Emerging Technologies In Aseptic Processing: Hype Vs. Operational Reality
- Use Of AI In FDA Inspection Activities: Strategies For Effective Preparation
- A Comparison Of 6 Analytical Validation Guidelines Using Data Envelopment Analysis
- Inside AstraZeneca's Fully Electrified Cell Therapy Facility
- AI Has Arrived In Biotech CMC Amid Patchwork Governance
- Driving Gene Therapy Beyond Rare Disease Will Define The Next Era Of CGT
- CDMO Selection: Start With The Relationship, Not The RFP
- Why FAT Should Confirm Alignment, Not Reveal Its Absence
CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS
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![cell-therapy-GettyImages-1494029118]( "Redefining The Analytical Frameworks Surrounding Capsid Characterization")
Redefining The Analytical Frameworks Surrounding Capsid CharacterizationModern AAV manufacturing demands precise capsid characterization to distinguish empty, partial, and full particles, as regulators now require rigorous purity and potency control for clinical safety.
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![GettyImages-1220382102-lab-research]( "A Scalable Platform To Revolutionize Gene Therapy Manufacturing")
A Scalable Platform To Revolutionize Gene Therapy ManufacturingDiscover how our innovative rAAV production platform can revolutionize your gene therapy pipeline with unparalleled yield, quality, and scalability.
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![SUS - Image_Case_study_automating_450x300]( "Automating The Process Of Filling Media Into Bottles")
Automating The Process Of Filling Media Into BottlesLearn how a vaccine manufacturer using a wide range of containers for media and buffer filling was able to increase efficiency by 70% with an automated closed-system solution.
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![GettyImages-2169909644-celll-meabolism-human]( "Novel Cardiotoxicity Evaluation Method Using iPS-Derived Cardiomyocytes")
Novel Cardiotoxicity Evaluation Method Using iPS-Derived CardiomyocytesDiscover how real-time monitoring of glucose and lactate in iPS-derived cardiomyocytes reveals subtle drug-induced metabolic shifts that traditional screening methods often fail to detect.
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![GettyImages-1166528597-scientist-lab-equipment-tubing]( "Automated PUPSIT For Drug Product Applications")
Automated PUPSIT For Drug Product ApplicationsAutomated filtration systems streamline PUPSIT, leak testing, and integrity checks to ensure sterile drug product processing. Learn how these methods improve contamination control and compliance.
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![mRNA GettyImages-1356994684]( "Levers To Optimize The IVT Reaction For Increased mRNA Yield")
Levers To Optimize The IVT Reaction For Increased mRNA YieldMastering IVT yield requires balancing magnesium and nucleotide ratios. Learn how specific buffers and pyrophosphatase optimize mRNA synthesis for scalable, high-quality therapeutic production.
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![GettyImages-493957253 microscope]( "Factors Influencing CD34+ Cell Collection Efficiency In Leukapheresis")
Factors Influencing CD34+ Cell Collection Efficiency In LeukapheresisEfficiently collecting sufficient peripheral blood stem cells is paramount for successful transplantation, necessitating a deeper understanding of influencing factors and procedural nuances.
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![CPC - CGT processing]( "New Robot-Compatible Sterile Connectors Enhance Cell Therapy Manufacturing")
New Robot-Compatible Sterile Connectors Enhance Cell Therapy ManufacturingDiscover how automating sterile fluid transfers removes human contamination risks, solves operator shortages, and reduces cell therapy manufacturing costs by up to 74%.
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![GettyImages-1746637448-laboratory-tablet-analysis-vial]( "Liquid Biopsy-Based Detection Of PIK3CA Mutations From cfDNA")
Liquid Biopsy-Based Detection Of PIK3CA Mutations From cfDNADiscover how ultra-sensitive digital PCR workflows use an innovative system to enable precise detection of rare PIK3CA mutations in cfDNA and advance personalized cancer treatment.
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![Femto-Pulse_Agilent_0260_Screen]( "Comparison Of Constant- And PulsedField Electrophoresis")
Comparison Of Constant- And PulsedField ElectrophoresisAccurate sizing of large DNA fragments is crucial in long‑read sequencing. Examine how different electrophoresis methods perform with 10–20 kb smears and how to choose the most reliable approach.
NEWSLETTER ARCHIVE
- 06.13.26 -- Cell & Gene Newsletter - Best Of May
- 06.12.26 -- Why Cell And Gene Therapy Has Not Reached More Patients — And Why Clinical Operations Is The Bridge
- 06.11.26 -- Translating Discovery Into Clinical Success
- 06.11.26 -- Bridging Innovation And Manufacturing In Cell & Gene Therapy
- 06.11.26 -- Why Contamination Control By Design Should Matter To Your CDMO
- Driving Gene Therapy Beyond Rare Disease Will Define The Next Era Of CGT
- CGT Manufacturing Shifts From Capacity To Strategy
- Dr. Peter Marks On Why Gene Therapy May Need A New Regulatory Playbook
- Regeneron Advances In Vivo Gene Therapy For Hearing Loss
- Sana, Mayo Clinic Advance A New Model For Cell Therapy Delivery In T1D
CELL AND GENE CONTENT COLLECTIONS
While there are opportunities to scale, there are also manufacturing gaps, capacity issues, and production timelines that require improvement to do so. And then, of course, there’s cost. Because scale up and scale out are significant to everyone in the sector, we’ve curated insightful editorial that addresses the most important aspects of scalability.
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