CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Direct And Rapid Multi-Attribute Monitoring Of Intact Monoclonal Antibodies By icIEF-UV/MS

  Explore a novel integrated workflow and system that offers direct chip-based integration of imaged capillary isoelectric focusing (icIEF) with mass spectrometry (MS).

• Addressing The Challenges In Lentivirus Harvest Clarification

  Traditional depth filtration struggles with lentiviral harvest clarification, leading to low yields and high costs. However, single-use centrifugation offers a promising alternative.

• EHR-To-EDC Success In A Complex, Adaptive Platform Trial

  I-SPY 2, one of the longest-running adaptive platform trials in oncology, is revolutionizing breast cancer research through a dynamic, data-driven approach to evaluating novel therapies.

• Development Of Endothelial-Cord Cell Banks And Blood Stem Cell Products

  Leverage our proven cGMP expertise in cell therapy manufacturing, from primary tissue processing to large-scale production for clinical trials.

• Studying The Spatial Architecture Of Glioblastoma

  Explore how intra-tumor heterogeneity (ITH) impacts cancer progression and therapy resistance with advanced imaging platforms and custom antibody panels to reveal the spatial architecture of glioblastoma (GBM).

• A Hybrid Modeling Approach To Accelerate Media And Feed Development

  Explore the outcomes of a study focusing on building a mechanistic model to determine the growth kinetics of a CHO-based process producing a mAb.

• Rapid, Automated, At-Line Adenovirus Quantitation

  Gain insight into how a high-throughput capsid assay for rapid AV quantification was developed using an innovative Bio-Layer Interferometry (BLI) platform that offers high precision and reliability.

• The Rescue Option: Course Correcting Struggling Clinical Trials

  The willingness to seek expert support from Rescue CROs when clinical trials face critical challenges is not a sign of weakness but a demonstration of accountability and commitment to excellence.

• Optimizing TFF And SPTFF For High-Concentration mAb Formulations

  Discover the critical role of formulation buffer composition in stabilizing monoclonal antibodies during tangential flow filtration, a process involving ultrafiltration and diafiltration under high pressure and shear forces.

• UpTempo Plasmid DNA Platform

  Gain insight into these end-to-end plasmid DNA solutions, leveraging robust cGMP-compliant processes and single-use manufacturing platforms to accelerate your cell and gene therapy programs.