CoRegen’s investigational autologous cell therapy, CRG-150, is designed to disrupt tumor-driven immune suppression by knocking out SRC-3 in Tregs, potentially exposing solid tumors to the patient’s own immune response without lymphodepletion.
- What Goes Into Restarting A Shelved Orphan Drug Candidate?
- A Much-Improved Approach For Understanding And Managing Safety Risks
- Immune Reset In Rheumatology: Moving Beyond Disease Suppression Toward Durable Remission
- CSV Assumes The AI System Sits Still — It Doesn't.
- Building Antigen-Specific Immune Tolerance For Autoimmune Disease
- July Update — U.S. Generic Drug Tariffs: Implications For Pharma And Outsourcing
- Combination Cell Therapy's Clinical Success Hinges On Manufacturability
- Are Biopharma Companies Outsourcing Their Ability To Think?
CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS
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![GettyImages-576919878-analytics-computer-testing-research-data]( "Advancing An Integrated Biopharma Workflow Strategy")
Advancing An Integrated Biopharma Workflow StrategyGlobal research teams were generating critical data in disconnected systems, hindering collaboration. Explore how unified workflows and a shared data backbone strengthen efficiency.
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![GettyImages-1200984194 elderly mobility]( "Delivering Specialist Neurology Support")
Delivering Specialist Neurology SupportExplore a strategic approach to a Parkinson’s disease trial that leveraged a global infrastructure and multilingual workforce to provide seamless operational and clinical support.
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![GettyImages-675822742 bioreactor]( "Addressing The Challenges In Lentivirus Harvest Clarification")
Addressing The Challenges In Lentivirus Harvest ClarificationTraditional depth filtration struggles with lentiviral harvest clarification, leading to low yields and high costs. However, single-use centrifugation offers a promising alternative.
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![GettyImages-1903972230 Sustainability Concept, Green Forest With Globe Earth]( "2024 Global Biopharma Sustainability Review")
2024 Global Biopharma Sustainability ReviewWhat steps is the biopharma industry taking to enhance sustainability? What challenges does biopharma encounter? And how can the entire industry draw lessons from the companies setting the standard?
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![GettyImages-1787595822-virus-viral-bacteria-cell]( "Application Of A Dual Spiking Strategy In Viral Clearance Studies")
Application Of A Dual Spiking Strategy In Viral Clearance StudiesExplore how an alternative spiking strategy can streamline viral clearance studies, reduce material demands, and maintain compliance while addressing the challenges posed by MLV and MMV.
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![GettyImages-931182764 Cheerful Office Workers On Laptops]( "Reframing Clinical Vendor Selection")
Reframing Clinical Vendor SelectionExplore a platform that enables seamless vendor selection as well as cross-functional collaboration with built-in templates and tailored question libraries that simplify proposal creation and review.
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![Delivering Complex Oncology Trials At Scale]( "Delivering Complex Oncology Trials At Scale")
Delivering Complex Oncology Trials At ScaleParexel delivered two complex, global Phase III prostate cancer trials by aligning site selection, logistics, imaging workflows, and RAM regulatory expertise—achieving faster enrollment and on‑time execution.
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![GettyImages-2217414221 manufacturing, tablet]( "Essential Strategies For Effective Viral Clearance Studies In Biologics Manufacturing")
Essential Strategies For Effective Viral Clearance Studies In Biologics ManufacturingStrengthen your viral safety strategy by applying science- and risk-based approaches to viral clearance planning, ensuring robust data, regulatory compliance, and patient protection.
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![GettyImages-1220382102-lab-research]( "Expansion Of Human Umbilical Cord-Derived MSCs")
Expansion Of Human Umbilical Cord-Derived MSCsDiscover how high-quality, multipotent stromal cells are efficiently produced for regenerative medicine. Learn about their impressive viability and critical marker expression for therapeutic uses.
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![CPC - aseptic processing]( "The Case For Modernizing Small-Volume Aseptic Processing")
The Case For Modernizing Small-Volume Aseptic ProcessingTube welding and biosafety cabinets present significant costs and risks for small-volume aseptic processing. Modern single-use aseptic connectors offer a more efficient alternative.
NEWSLETTER ARCHIVE
- 08.21.26 -- Smarter Workflows For Cell & Gene Production
- 08.21.26 -- Rewriting The Playbook For Stargardt Disease With Shannon Boye, Ph.D.
- 08.20.26 -- Are Biopharma Companies Outsourcing Their Ability To Think?
- 08.19.26 -- Building A More Scalable Gene Therapy Program
- 08.19.26 -- Scaling Human-Relevant Science For Biologics Development
- Reimagining Solid Tumor Immunotherapy With SRC-3-Edited Tregs
- Building Antigen-Specific Immune Tolerance For Autoimmune Disease
- Solving Vector Yield Challenges Starts Long Before Manufacturing
- Full FDA Approval For TECELRA Marks More Than A Regulatory Win For Solid Tumors
- FDA Approval Of TREGZI Signals A New Era For Precision Engineered Cell Therapy
CELL AND GENE CONTENT COLLECTIONS
While there are opportunities to scale, there are also manufacturing gaps, capacity issues, and production timelines that require improvement to do so. And then, of course, there’s cost. Because scale up and scale out are significant to everyone in the sector, we’ve curated insightful editorial that addresses the most important aspects of scalability.
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