CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• In Vivo RNA Tuning For Liver Gene Editing Efficiency

  RNA sequence and guide modifications, delivery platform design, and dose optimization all contribute to improved gene editing outcomes, which offers a clearer path toward safer, more potent, and scalable mRNA-based therapeutics.

• Virus Reduction And Impurity Removal

  Examine a DOE-based study that reveals how buffer conditions impact virus and impurity clearance using a mixed-mode resin, as well as gain practical guidance for optimizing downstream purification.

• A Duplex Assay For Quantification And Qualification Of AAV

  Adeno-associated virus is a key gene therapy vector. Explore how digital PCR offers precise, standard-free quantification with improved consistency and inhibitor tolerance over traditional qPCR methods.

• Ready To Demystify Organoids?

  Organoids are transforming biomedical research. Explore their top applications, research workflows, key challenges, and dissociation techniques in this comprehensive guide to personalized medicine.

• Driving Digital Excellence In Life Sciences

  The life sciences industry is rapidly evolving through digital transformation and agility. Discover why embracing modern technologies is essential to thrive in today’s competitive landscape.

• Rescuing A Global Program For NDA Success

  Explore the collaboration that enabled FDA approval of a novel chronic-condition therapy, rescued a high-risk program, and demonstrated a unified “one-team” approach by reworking the sponsor's SAP.

• Automated Library Prep For A Nanopore DNA Barcoding Protocol

  A streamlined workflow reduces reagent use and hands‑on time while preserving long‑read sequencing quality. See how multiplexed offer an efficient option for scaling or mobilizing sequencing efforts.

• Rescuing A Global Full-Service Phase III Trial For A Late-Stage Oncology Biotech

  This case underscores the expertise employed in a comprehensive strategy and set of services that were used to salvage a Phase III clinical trial for ovarian cancer and ensure its timely completion.

• Three-Dimensional Linkage Analysis With Digital PCR For Genome Integrity

  A cost-effective approach with a comprehensive AAV analytical package holds the potential to advance the application of rAAV in cell and gene therapy for the treatment of human diseases.

• Application Of A Dual Spiking Strategy In Viral Clearance Studies

  Explore how an alternative spiking strategy can streamline viral clearance studies, reduce material demands, and maintain compliance while addressing the challenges posed by MLV and MMV.