CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Bulk Filling Of Drug Substance | Accurate Aliquoting

  Bulk filling drug substances in traditional facilities is often a lengthy, manual process where operators are relied upon to adjust pump controls to achieve accurate filling. This method, spanning multiple shifts, increases process risk through errors that can compromise accuracy.

• Streamline Analytical Tech Transfer Through Analytical Target Profile

  Analytics debt in CGT can derail timelines and budgets. Learn how early ATP planning and cross-functional alignment can eliminate costly setbacks and accelerate IND approvals.

• AAV Viral Titering Using Nanoplate-Based Digital PCR

  Examine how nanoplate-based digital PCR streamlines AAV titering, providing faster results and greater accuracy, advancing gene therapy development from the lab to the clinic.

• Five Essentials For Accurate Oligonucleotide Chemistry

  Explore five key areas in oligonucleotide chemistry where improvements will have a huge influence on your synthesis quality.

• Optimizing DPI Production: Filling Technologies For Precision And Performance

  Developing effective dry powder inhalers requires expertise across multiple disciplines, from particle engineering and device technology to manufacturing science and regulatory knowledge.

• Maintain Sterility And Ease In CGT Development, Including Cryopreservation

  Sterile connectors streamline cell and gene therapy processes while maintaining sterility. By withstanding extreme temperatures and cryoprotectants, they can ensure product viability during cryopreservation.

• Sterilizing Grade Filter Performance With Biologic Drugs

  Examine the throughput performance of sterilizing grade filters across moderate-to-high concentrations of mAbs and immunoglobulins as well as how filter selection can impact your process.

• Guiding Principles For Process Development And IND Readiness

  Observe how a milestone-driven risk management strategy streamlines cell therapy development, reduces uncertainty, and aligns early decisions with long-term commercialization and regulatory success.

• Scaling Of Impingement Jets Mixing For LNP Drug Production

  Delve into the intricacies of Impingement Jets Mixing (IJM) technology and its pivotal role in the scalable and reproducible production of Lipid Nanoparticles (LNPs) for drug delivery.

• Efficient Late-Stage Development Of Biologics

  Reducing biologics manufacturing costs requires strategic late-stage process development, yield optimization, scale-up, and raw material substitution—all while maintaining product quality and regulatory compliance.