CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Epigenetics Application Guide

  To fully understand biology and disease mechanisms, it is crucial to explore the role of epigenetic factors. Explore how epigenetic regulation works and methods to study these essential components.

• Rescuing A Global Program For NDA Success

  Explore the collaboration that enabled FDA approval of a novel chronic-condition therapy, rescued a high-risk program, and demonstrated a unified “one-team” approach by reworking the sponsor's SAP.

• Manufacturing ADCs: Extractables In Single-Use Systems

  Antibody-drug conjugates offer targeted cancer treatment with reduced toxicity. Discover how single-use technologies simplify ADC manufacturing to ensure safety, flexibility, and efficiency.

• Scale-Up Approaches For Culturing Adherent Cells

  For successful scale-up, see how optimizing process parameters such as attachment methods, gassing, and agitation can help reduce cell environmental stress, ultimately improving productivity.

• Ensuring Supply Through Speed And Transparency

  Through speed, transparency, and close collaboration, the pharmaceutical company was able to switch vendors seamlessly, maintaining virtually uninterrupted manufacturing operations.

• Expansion Of Human Bone Marrow-Derived MSCs

  Achieving over 870 million viable, quality mesenchymal stem/stromal cells is possible. This efficient cell culture method scales bone marrow-derived MSCs for clinical needs.

• A Human-Relevant Model Of The Liver Sinusoid

  This organ-on-a-chip model minimizes drug absorption while maintaining the essential architecture. Explore the specifications of this product engineered to model the human liver.

• Matrigel Dome Assay And Drug Screening Of Colorectal Cancer Organoids

  Using CRC organoids and bioprinting, explore the automation of dome assays to evaluate drug responses and delve into the insights from image-based end-point assays on the efficacy of anti-cancer treatments.

• Tailoring Viral Clearance Study Design

  Viral‑clearance studies need phase‑appropriate design, strong virus stocks, modality‑specific risk assessment, and alignment with evolving regulations for reliable safety outcomes.

• How To Design And Evaluate Bispecific Antibodies (BsAbs)?

  Bispecific antibodies combine two antigen-binding sites to enhance efficacy and safety. Their design requires structural strategy, MOA-based evaluation, and rigorous screening for optimal therapeutic performance.