CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Bringing Clinical Trials To Everyone's Backyard

  Learn how bringing clinical trials to any community around the world is not only possible but also increases patient access and reach and improves recruitment and retention.

• CE-SDS Analysis Of Etanercept Using The BioPhase 8800 System

  In this study, a system with multi-capillary capabilities was used to analyze etanercept by bapillary electrophoresis-sodium dodecyl sulfate (CE-SDS).

• Successful Cell-Based ADA Collaboration In mRNA Gene Replacement Therapy

  A biotech firm developed a rapid, sensitive, cell-based ADA assay through collaborative innovation, reducing variability and turnaround time while improving performance for mRNA gene therapy.

• Evaluating Cell Culture Medium Performance In CAR-T Processes

  This study examines the expansion, functionality, and phenotype of CAR-T cells cultured in the CellGenix® GMP T cell culture medium (TCM) compared to other commercially available T cell media.

• A Mobile BSL-2 cGMP Cleanroom Delivered In Less Than 3 Weeks

  A mobile cleanroom facility was needed for manufacturing a new monoclonal antibody product for phase 1 clinical trials. The facility had to have the ability to be repurposed for additional applications.

• A Cost-Effective Alternative To Traditional Protein A Resin Chromatography

  Examine this cost-effective, efficient alternative to traditional Protein A resin chromatography for mAb production to enhance productivity and reduce costs.

• High-Performance Extraction And Quantitation Of Host-Cell Residual DNA

  This study presents a high-efficiency method for extracting and quantifying residual DNA from host cells using a semi-automated, high-throughput workflow.

• Controlled Production Of MSC-Derived Extracellular Vesicles In Stirred-Tank Bioreactors

  Learn how stirred-tank bioreactors overcome the scalability limitations of static culture for MSC-EV production, while Raman spectroscopy provides unprecedented real-time quality monitoring during production.

• Alternatives To CRISPR-Cas9: Nucleases For Next-Gen Therapy

  Alternatives to CRISPR-Cas9 address limitations like delivery challenges and off-target effects. Emerging nucleases offer improved specificity, smaller sizes, and therapeutic applications.

• Efficient FBS Removal And Cell Concentration In Vero Cell Cultures

  Benefit an instrument that is showing potential to optimize Vero cell culture processes through concentration and FBS removal using PBS as the wash solution.