CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Rapid Production Of Assay Ready Cells For GPCR Drug Discovery

  Accelerate drug discovery by leveraging transiently transfected assay-ready cells. This method improves assay sensitivity and reduces variability for GPCRs.

• Raise Your Standards With Downflow Booth Airflow Containment

  Ensure personnel safety during hazardous material handling by mastering airflow dynamics and containment screens. Learn to achieve low exposure levels through advanced HEPA filtration methods.

• A Scalable Manufacturing Platform For The Purification Of Stem Cell Derived Exosomes

  EV production scale increases require paired robust, scalable, and cost-effective downstream processes. Process parameters can be tailored for therapeutic exosome programs and allow for maximum exosome recovery.

• Maximizing MSC Yield And Quality: A Comparative Media Study

  Maximize mesenchymal stem cell (MSC) expansion with a simplified culture process. New data demonstrates a high-performance, xeno-free media that eliminates the need for coatings or media exchanges.

• Rescuing A Global Program For NDA Success

  Explore the collaboration that enabled FDA approval of a novel chronic-condition therapy, rescued a high-risk program, and demonstrated a unified “one-team” approach by reworking the sponsor's SAP.

• 12-Day Stability Of PRIME-XV T Cell Expansion Supplemented With CTGrade GMP Cytokines

  Discover how T-cell culture media supplemented with key cytokines can maintain full functionality and support robust expansion for up to 12 days at room temperature.

• Enhancing CRISPR Knock-In And Knock-Out

  Achieve scalable, non-viral CRISPR delivery for T cells. The next-generation electroporation platform provides robust, efficient gene editing in large-scale volumes.

• 21% Of CGT Clinical Holds Stem From CMC Issues. What Does This Tell Us?

  Cell and gene therapy (CGT) trials account for nearly 40% of all clinical holds reported by the NIH, with over 21% caused by CMC issues, often delaying approvals by over 6 months.

• Automation Of iPSC Culture, Passaging, And Expansion

  Find out how iPSC-derived models enable researchers to generate diverse cell types and tissues as well as how automation reduces the labor-intensive culturing process with AI-powered decision-making.

• Quantifying Lentiviral Physical Titer Using The QIAcuity dPCR System

  Streamline lentiviral vector analytics with our direct RT-dPCR method. Achieve precise, reproducible results to accelerate safe, effective gene therapies with enhanced quality control.