CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Evolving Landscape Of Payer Coverage For CGTs: Trends And Insights

  Examine how proactive payer engagement and robust clinical evidence regarding comparative effectiveness and durability of response can overcome significant reimbursement barriers and enhance patient access.

• Optimizing Virus Bank Manufacturing

  Gain insight into two cases where clients were enabled to overcome obstacles during virus bank manufacturing.

• mRNA Purification Using Anion Exchange Chromatography At Ambient Temperature

  Explore how anion exchange chromatography with dual gradient elution enables efficient mRNA purification at ambient temperature.

• Fast And Accurate Detection Of Alzheimer's Disease Targets

  In this study, the detection of three Alzheimer’s disease targets are highlighted: Human BDNF (Brain-derived neurotrophic factor), Tau, and TREM2 (Triggering receptor expressed on myeloid cells 2).

• Ensuring cGMP Compliance In Cell And Gene Therapy Manufacturing

  Discover how adhering to strict GMP guidelines and advanced equipment design ensures that complex, sterile cell and gene therapies are safely and effectively delivered.

• Non Animal Origin Squalene For High-Risk Applications

  Explore an ethical and sustainable alternative to shark-derived squalene that is backed by robust data to deliver identical performance in vaccine formulations without environmental compromise.

• Intuitive Bioprocess Scale-Up From Bench Scale To Pilot Scale

  This study explores scaling a high-demand fed-batch process from bench to pilot scale, highlighting control parameter differences at 50L and 500L while maintaining consistent growth and product titers.

• A Digital Solution Embeds Quality Into Cellular Therapeutics Production

  Discover how Dendreon cut review and release time by nearly 50% while maintaining a 99% right-first-time rate, which boosts collaboration, visibility, and operational efficiency across teams.

• Screening Peptones, Including "Titration And Blending" Protocol Examples

  Dive into the importance of peptone selection, instructions for reconstituting peptone powders for mammalian cell culture, and discover starter packs containing commonly used peptones for specific applications.

• Understanding Immunogenicity In AAV Gene Therapy

  As adeno-associated virus-based gene therapies progress toward clinical use, effectively managing immunogenicity risk is critical to patient selection, therapeutic durability, and regulatory success.