CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Overcoming Bispecific Antibody Purification Challenges

  Enhance the quality and safety of your BsAb therapeutics with a highly efficient with the right chromatography hydroxyapatite media.

• Optimize T Cell Phenotype With One-Step Isolation And Activation

  This comparative bench-scale study features active-release beads that could improve the reliability, consistency, and longevity of cell therapy treatments.

• Cytokine-Mediated Inflammation In A Relevant Preclinical Model

  Learn about a novel preclinical model and how it enables the study of cytokine-mediated barrier inflammation mechanisms as well as the efficacy of anti-inflammatory therapeutics.

• Assessment Of Compound Toxicity Effects With High-Content Imaging

  3D cellular models and bioprinting enhance drug safety predictions and offer precise spatial control. Explore an automated method for generating liver models to improve reproducibility and reliability in toxicity testing.

• Advances In Flow-Through Technology To Enhance mAb Polishing

  Optimize your monoclonal antibody purification with cutting-edge flow-through chromatography. Learn how POROS resins enhance polishing efficiency, improve aggregate removal, and streamline bioprocessing.

• Fast And Scalable Fc Quantitation In Supernatants

  In biopharmaceutical development, the Fc PAIA Titer assay offers a fast, cost-effective, and automatable solution for high-throughput Fc quantification to enhance efficiency, support research, and accelerate production advancements.

• Producing MSC-Derived Cell Therapies From Isolation To Large-Scale Expansion

  Explore the journey of producing MSC-derived cell therapies, from initial isolation and expansion to final product formulation and storage, and learn how to optimize each step.

• High-Yield Expression Of Complex Proteins From Stable Pools

  This study presents the development of apoptosis-resistant CHO cell lines (DKO1 and DKO2), using electroporation technology, with the goal of enhancing biotherapeutic production.

• How Blast Freezing Affects The Quality Of Bottled Drug Substance: Test Results And Insights

  Uneven ice formation during bottle freezing creates a "Volcano Effect," pushing solutes into highly concentrated zones. This test-based study explains this risk to drug substance quality.

• Improving Methodologies For iPSC Manufacturing And Differentiation

  Learn how next-generation workflows are being developed to streamline iPSC manufacturing, enhance differentiation strategies, and overcome the hurdles of scalability and consistency.