CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Alerion Microbubble Cell Separation System Used For T Cell Negative Selection

  Discover how the Alerion™ Microbubble Cell Separation System outperformed standard magnetic methods in T cell recovery, speed, and scalability — achieving higher cell quality with Akadeum’s innovative microbubble technology.

• Building A Smarter Potency Strategy For Bispecific Antibodies

  A biotech company needed a regulatory-ready potency strategy for a bispecific antibody. This organization combined orthogonal analytics with functional assays.

• Enabling The Rapid, Reproducible Manufacturing Of TranspoCART Cells

  Learn how an innovative technology streamlines Transpocart cell production, making rapid and consistent manufacturing a reality for cell therapies.

• Scaling Manufacturing For Global Success

  This collaboration demonstrates how a partnership-driven approach, combined with technical expertise, can deliver scalable, efficient, and reliable manufacturing solutions that support successful global commercialization.

• Optimized Product Recovery Using The Drug Product Filtration System

  Explore strategies to maximize drug product recovery during sterile filtration, minimize hold-up volume, and reduce dilution after PUPSIT to ensure higher yield, improved efficiency, and less waste.

• Advances In Analytical Method Selection And Technology Transfer

  Successful analytical method transfer is crucial for product quality and regulatory compliance. Learn best practices for tech transfer, including how gap assessments mitigate common risks and streamline bioprocessing.

• Application Of A Dual Spiking Strategy In Viral Clearance Studies

  Explore how an alternative spiking strategy can streamline viral clearance studies, reduce material demands, and maintain compliance while addressing the challenges posed by MLV and MMV.

• Developing A Robust Crystallization Process For A High-Molecular-Weight Peptide

  Scaling peptide crystallization is complex, with solid forms, polymorphic impurities, and solvent constraints all impacting quality and manufacturability.

• A Comparison To Traditional Clone Screening Platforms

  See how 46 CHO clones performed across automated, deep-well, and microbioreactor fed-batch cultures, using cell density, viability, and IgG concentration to evaluate clone performance.

• Comparing In-Line Vs At-Line Variable Pathlength Tech For UF/DF

  Discover how rapid amino acid profiling improves media insight, detects variability, and supports real-time optimization for stronger bioprocess control, as well as strategies to reduce risk.