CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Engineering Challenges In Designing Pharmaceutical Isolators

  Designing pharmaceutical barrier systems requires balancing strict cleanliness with practical engineering. Explore key factors for optimizing airflow and ergonomics.

• A Paradigm Shift From Glass Benchtop Bioreactors

  Learn how a bench-scale single-use bioreactor offers process development advantages over traditional glass systems, including higher efficiency, increased productivity, and enhanced sustainability.

• Targeted Indication Selection Using Adaptive Design

  What is a Simon 2-stage design, and how was it used to enable each tumor-specific cohort in a Phase 2, multi-cohort oncology trial to be independently assessed for objective response rates?

• Automation And Digital Solutions Can Help You Reach Your mRNA Manufacturing And Sustainability Goals

  Explore how digital solutions help streamline mRNA manufacturing by reducing costs, improving efficiency, and supporting sustainability by creating paperless processes for emerging therapeutics.

• Form Fill And Seal Label Applicator For Drug Packaging

  Discover a solution that ensures particularly efficient and reliable vertical and horizontal form fill and seal machine labeling.

• CAR Expression Detection Using Fluorescent Labeled Proteins, Flow Cytometry

  Learn how site-specific fluorescent labeling addresses key challenges in flow cytometry-based evaluations by enhancing assay sensitivity, reducing variability, and ensuring reliable results.

• Novel Cardiotoxicity Evaluation Method Using iPS-Derived Cardiomyocytes

  Discover how real-time monitoring of glucose and lactate in iPS-derived cardiomyocytes reveals subtle drug-induced metabolic shifts that traditional screening methods often fail to detect.

• Metabolic Phenotype Preservation And Suitability Of hMSCs Cultivated In Stirred Tank Bioreactors

  Learn how researchers demonstrated scalable hADSC expansion in stirred-tank bioreactors using microcarriers, achieving metabolic stability and consistent growth for cell therapy applications.

• Assessing The Success Of CRISPR Gene Therapies Using ddPCR Technology

  Achieve high-fidelity results in gene therapy research. Discover how absolute quantification overcomes traditional limitations to provide the precision needed for validating CRISPR edits.

• Scale-Up Approaches For Culturing Adherent Cells

  For successful scale-up, see how optimizing process parameters such as attachment methods, gassing, and agitation can help reduce cell environmental stress, ultimately improving productivity.