CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Advances In Analytical Method Selection And Technology Transfer

  Successful analytical method transfer is crucial for product quality and regulatory compliance. Learn best practices for tech transfer, including how gap assessments mitigate common risks and streamline bioprocessing.

• Why Membrane Matters In AAV Filtration

  Gene therapy is revolutionizing medicine to offer one-time treatments. Find out how AAV vectors are leading the way to optimize production and make these life-changing therapies accessible.

• 21% Of CGT Clinical Holds Stem From CMC Issues. What Does This Tell Us?

  Cell and gene therapy (CGT) trials account for nearly 40% of all clinical holds reported by the NIH, with over 21% caused by CMC issues, often delaying approvals by over 6 months.

• A Better Immune Response To Vaccination: Using Lymphoid Follicle Organ-Chips

  Discover a first-of-its-kind human LF-Chip containing B, T, plasma and antigen-presenting cells to test functional immunization responses to vaccines and adjuvants in vitro.

• Expanding Patient Access To Cell And Gene Therapies: Optimizing Channel Strategy

  Rare disease innovation demands robust channel strategies for patient access. Learn how a patient-centric approach, logistical solutions, and strong partnerships are key to successful patient access.

• Revolutionizing Lentiviral Vector Manufacturing For In Vivo, Ex Vivo CAR-T Therapies

  Discover how scalable, cost-effective, and high-quality lentiviral vector manufacturing can accelerate both ex vivo and emerging in vivo CAR-T therapies.

• Automated DNA Clean-Up Using Magnetic Bead-Based Methods

  Discover how to improve DNA clean‑up through a precise magnetic bead–based workflow, as well as how optimized liquid handling enhances yield, purity, and reproducibility for higher confidence in results.

• Optimize T Cell Phenotype With One-Step Isolation And Activation

  This comparative bench-scale study features active-release beads that could improve the reliability, consistency, and longevity of cell therapy treatments.

• Guiding Principles For Process Development And IND Readiness

  Observe how a milestone-driven risk management strategy streamlines cell therapy development, reduces uncertainty, and aligns early decisions with long-term commercialization and regulatory success.

• Screening Peptones, Including "Titration And Blending" Protocol Examples

  Dive into the importance of peptone selection, instructions for reconstituting peptone powders for mammalian cell culture, and discover starter packs containing commonly used peptones for specific applications.