CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

  • Use of Liquid Biopsy for Cancer Diagnosis and Monitoring
    Use of Liquid Biopsy for Cancer Diagnosis and Monitoring

    Liquid biopsy is a noninvasive method used for the diagnosis and monitoring of disease states, including cancer. Instead of physically taking a biopsy of the affected tissue, cell-free DNA (cfDNA), circulating tumor DNA (ctDNA, a subset of cfDNA present only in tumors), or cancer cells in suspension (also known as circulating tumor cells, CTCs) are collected from blood or other fluids.

  • Guidelines For Phasing Variants Using Bio-Rad Droplet Digital System
    Guidelines For Phasing Variants Using Bio-Rad Droplet Digital System

    We describe a Droplet Digital PCR-based method, Drop-Phase, which allows users to quickly and accurately phase genomic variants. We successfully phased pairs of CFTR variants and show the methodology can measure linked species that are up to 210 kb apart. This method can be used to phase variants discovered through sequencing or to screen unsequenced individuals for a particular haplotype of interest for clinical trials.

  • What Cleanroom Build Method Is Best For You?
    What Cleanroom Build Method Is Best For You?

    Your future cleanroom is a critical asset, it is not just another construction project. The investment you make in the cleanroom facility is significant and it should perform for years to come. Learn the relative strengths and weaknesses of various cleanroom construction methodologies that are being implemented within the marketplace.

  • Intracellular Flow Cytometry Tips And Tricks
    Intracellular Flow Cytometry Tips And Tricks

    Helpful tips such as carefully choosing the most suitable fixative and permeabilization reagents as well as other factors that should be considered when designing intracellular flow experiments.

  • The Potential For CRISPR Gene Editing In HIV
    The Potential For CRISPR Gene Editing In HIV

    The advent of CRISPR as a gene editing tool continues to revolutionize drug discovery and development.

  • Virus Reduction Of An Affinity Capture Step - Viral Clearance For Protein A
    Virus Reduction Of An Affinity Capture Step - Viral Clearance For Protein A

    Evaluating how much a process step contributes to viral clearance is an essential part of process validation in order to be sure you are manufacturing safe drugs. Learn more about how HiScale 10/40, packed with MabSelect PrismA, is a reliable choice for the capture step in a virus clearance study.

  • Single-Use Systems For Shipping Frozen Drug Materials – Every Component Counts
    Single-Use Systems For Shipping Frozen Drug Materials – Every Component Counts

    Integrated single-use freeze-thaw assemblies with reliable component parts, such as the connectors supplied by CPC, have become the primary implementation choice for achieving successful drug substance transfers between manufacturing facilities.

  • Water-free vs Water Bath Cell Thawing
    Water-free vs Water Bath Cell Thawing

    Alternative to water baths for thawing frozen cells

  • Cell & Gene Therapies: SUT Connection Lessons From Biotech
    Cell & Gene Therapies: SUT Connection Lessons From Biotech

    Single use connection technologies are expected to play a critical role in commercial manufacturing of cell and gene therapies. Learn about the types of connection technologies and selection considerations.

  • How To Implement Cleanroom Upgrades While Operating Your Facility
    How To Implement Cleanroom Upgrades While Operating Your Facility

    It goes without saying that upgrades during a manufacturing shutdown pose less risk as there are no products being produced, but there are instances when it is critical to expand capacity or modify functionality while maintaining some processing. Following are a steps to help maintain control of production and changes—and demonstrate proof of control—while keeping the involved workers and the products safe.

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CELL & GENE CONTENT COLLECTIONS

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What's the future of food traceability? Learn more in this free collection of articles highlighting recall prevention, a transparent brand-consumer relationship, and how to choose the right food traceability system.

CELL & GENE INDUSTRY EVENTS

Lyophilization - An Introduction to the Scientific Principles August 27 - 27, 2019
1pm-2:30pm EST, Online Training
The Top Method Validation Mistakes – And How to Avoid Them September 9 - 9, 2019
1pm-2:30pm EDT, Online Training
Pediatric Clinical Trials: Special Considerations and Requirements September 13 - 13, 2019
1pm-2:30pm EDT, Online Training
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