CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Delivering A Registrational GI Trial Through Ongoing Protocol Shifts

  A biotech developing bispecific antibodies partnered with a flexible CRO to launch its first U.S. GI oncology trial, requiring strategic insight and full-service clinical support.

• Simplify Process Scale-Up With An Innovative Single-Use Bioreactor

  Consistent cell growth and protein yields from 5 L to 5,000 L show how a unified bioreactor design can simplify scale-up, reduce risk, and accelerate upstream process development in bioproduction.

• Sterile Filter Membrane Selection For Cell Culture Media Filtration

  Membrane design and filtration capacity affect pressure, throughput, and scale-up. See how comparative testing reveals opportunities to reduce required filtration area, capsule use, and changeouts.

• Manufacturing ADCs: Extractables In Single-Use Systems

  Antibody-drug conjugates offer targeted cancer treatment with reduced toxicity. Discover how single-use technologies simplify ADC manufacturing to ensure safety, flexibility, and efficiency.

• Control pH Adjustment And Reduce Complexity

  Learn how automated, banded pH control uses dose-and-wait logic to limit overshoot, account for mixing and buffer effects, and maintain stable setpoints across changing fill volumes.

• Molecular Approaches To Streamline Cell Therapy Product Analytical Testing

  Learn how rapid molecular methods of cell therapy testing like qPCR for mycoplasma, sterility, and lentiviral quantification are key to accelerating product release and timely treatment delivery.

• Maintain Sterility And Ease In CGT Development, Including Cryopreservation

  Sterile connectors streamline cell and gene therapy processes while maintaining sterility. By withstanding extreme temperatures and cryoprotectants, they can ensure product viability during cryopreservation.

• Overcome Patient-Level Access Barriers For New Medicine

  Explore market access from the patient’s perspective and identify five aspects of how people get hold of medicine that should inform commercialization.

• Accelerating Cell Therapy Discovery With High-Throughput Electroporation

  Discover how high-throughput electroporation-based screening can compress your CAR-T optimization timeline while delivering reproducible, scale-ready results across multiple donor samples.

• Scalability And Reproducibility Of The AAV9 Capture Step

  Scaling gene therapies beyond rare diseases demands innovation. Discover a chromatography system that boosts efficiency, protects product integrity, and overcomes viral vector manufacturing challenges.