CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Factors Influencing CD34+ Cell Collection Efficiency In Leukapheresis

  Efficiently collecting sufficient peripheral blood stem cells is paramount for successful transplantation, necessitating a deeper understanding of influencing factors and procedural nuances.

• Injection Site Reaction Screening Methodology

  Optimize drug formulations for solubility at physiological pH to reduce injection site reactions, enable high-concentration dosing, and enhance patient comfort and compliance.

• Viral Disinfectant Efficacy Studies: Key Guiding Factors And Design Elements

  Achieving compliance and safety through Disinfectant Efficacy Studies (DES) is about adhering to regulations and committing to high standards of safety and quality of manufacturing operations.

• The Rescue Option: Course Correcting Struggling Clinical Trials

  The willingness to seek expert support from Rescue CROs when clinical trials face critical challenges is not a sign of weakness but a demonstration of accountability and commitment to excellence.

• A Comparative Analysis Between Liquid Nitrogen And Mechanical Freezers

  Explore the differences between liquid nitrogen and mechanical cryogenic freezers, and learn how each method supports scientific, medical, and industrial storage needs.

• Accelerate Cell Expansion And Sustain Viability With A Serum-Free Medium

  Discover how Corning's Insect Cell serum-free medium outperforms other commercial media in yield, doubling time, and cell viability by diving into the study results.

• Functional Characterization Of 3D Assembled Neurospheres

  Neural organoids and 3D spheroids offer advanced platforms for brain research and drug discovery. Discover how creating 3D neurospheres from iPSC-derived neurons and astrocytes aids in compound profiling and toxicity testing.

• Impact Of Media Selection

  To highlight the importance of media selection, a study was conducted assessing the effect of three commercially available cGMP grade medias and their influence on T-cell phenotype.

• Challenges, Methods, And Solutions For Obtaining Optimal Starting Material

  For innovative treatments like CAR-T and stem cell transplants, optimal starting material is key. Understanding collection challenges and new solutions helps ensure the best foundation for these therapies.

• Optimizing TFF And SPTFF For High-Concentration mAb Formulations

  Discover the critical role of formulation buffer composition in stabilizing monoclonal antibodies during tangential flow filtration, a process involving ultrafiltration and diafiltration under high pressure and shear forces.