CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Immunohistochemistry In Precision Medicine: From Biomarker To Clinical Trial Assay

  From preclinical validation to clinical implementation, immunohistochemistry (IHC) is essential in understanding target biology and ensuring drug safety and efficacy.

• Rapidly Assess Drug Response In 2D And 3D Breast Cancer Model Systems

  For years, 2D cell cultures have been crucial in drug discovery. Explore how 3D cultures offer more biologically relevant models today that enhance cancer research and drug efficacy assessments.

• How To Take Your Process To A Closed System

  Understand the critical considerations for implementing closed systems in bioproduction, from vessel selection to workflow customization for optimal efficiency and safety.

• Alerion Microbubble Cell Separation System Used For T Cell Negative Selection

  Discover how the Alerion™ Microbubble Cell Separation System outperformed standard magnetic methods in T cell recovery, speed, and scalability — achieving higher cell quality with Akadeum’s innovative microbubble technology.

• CRISPR Reagents Enable High Efficiencies Of Editing And HDR In iPSCs

  Achieving consistent Homology Directed Repair (HDR) in iPSCs requires optimized CRISPR design and workflows. See how advanced reagents and targeted enhancement strategies improve insertion efficiency.

• Case Study: Full Clonality Assessment Of CHO Cell Line

  In this case study, a comprehensive genetic analysis was performed on a transgenic Chinese hamster ovary (CHO) master cell bank to characterize the bank and provide high-confidence evidence of clonality.

• Addressing Plasmid DNA Challenges In Large-Scale AAV And Lentivirus Manufacturing Using dbDNA

  Plasmid DNA supply and regulatory concerns constrain large-scale viral vector manufacturing. Here, we examine whether enzymatically generated dbDNA can deliver comparable rAAV and rLV production outcomes.

• Executing A Complex Global Breast Cancer Trial In A Rapidly Evolving Treatment Landscape

  See how rapid site activation, strong oncology site relationships, and adaptive protocol management kept a complex global cancer trial on track amid evolving standards of care.

• Reshoring Pressure Meets Manufacturing Reality

  U.S. pharma can't reshore what domestic capacity can't absorb. Senior leaders from Takeda, Biogen, Eli Lilly, and others reveal why tariff pressure is colliding with a sterile fill-finish shortage, workforce gaps, and ADC capacity bottlenecks.

• Fluorescent Bacterial Colony Selection

  Fluorescent reporter genes simplify screening bacterial transformants. Discover a system that automates colony picking to enhance efficiency and precision with fluorescence imaging.