CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Highly Sensitive ELISAs In 90 Minutes

  Traditional ELISA methods are often limited by their relatively low throughput and need for multiple wash steps. Learn about a solution that overcomes these challenges and provides rapid results.

• A Temperature-Stable Replacement For Animal Trypsin In Cell Dissociation Applications

  Improve cell dissociation with a gentle, recombinant enzyme. This temperature-stable protease shows dissociation kinetics similar to porcine trypsin but with lower cell toxicity and greater overall purity.

• A Beginner's Guide To Sf9 Culture In Stirred-Tank Bioreactors

  Learn about the workflow steps for Sf9 cell expansion, virus preparation, and protein production in stirred-tank bioreactors, including GFP expression.

• Enabling Rapid, High-Yielding, Stable Cell Line Development

  Discover how to simplify and accelerate CHO-S stable cell line development, eliminating the need for extensive screening of candidate clones and specialized equipment.

• Scalability And Reproducibility Of The AAV9 Capture Step

  Scaling gene therapies beyond rare diseases demands innovation. Discover a chromatography system that boosts efficiency, protects product integrity, and overcomes viral vector manufacturing challenges.

• Seed Train Intensification Using High Cell Density Cryopreservation

  Streamline your upstream bioprocessing with seed train intensification. Discover how high cell density cryopreservation reduces scale-up time, boosts consistency, and enhances manufacturing flexibility.

• mRNA Manufacturing With Fed-Batch In Vitro Transcription

  A milliliter-scale approach to IVT optimization reveals how controlled feeding, precise pH management, and real-time monitoring can boost mRNA yield and streamline scale-up to larger bioreactor volumes.

• A Risk-Based Approach To Plasmid DNA And mRNA Process Development

  Balancing robust analytics and clinical readiness is key for early-phase pDNA and mRNA therapeutics amid structural complexity and regulatory challenges.

• Navigating CMC Regulation For Plasmid DNA In Gene Therapy

  Explore how evolving regulatory pathways and CMC innovation are shaping the future of gene therapy and viral vector production, plus what to consider when selecting a CDMO partner.

• An Innovative Approach To Streamline Raman Implementation

  Standard methods for building Raman spectroscopy models are often time-consuming and resource-intensive. Explore one-batch calibration and how its performance compares to other modeling techniques.