CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Stabilization Of RNA-Loaded Lipid Nanoparticles By Lyophilization

  Discover how lyophilization enhances RNA-based therapeutics by enabling storage at higher temperatures, which simplifies cold-chain logistics while preserving nanoparticle integrity and biological activity.

• A Paradigm Shift From Glass Benchtop Bioreactors

  Learn how a bench-scale single-use bioreactor offers process development advantages over traditional glass systems, including higher efficiency, increased productivity, and enhanced sustainability.

• A Model To Produce CAR-T, Anywhere

  Standardized point-of-care manufacturing overcomes cell therapy access, cost, and supply challenges, enabling regional centers to efficiently deliver high-quality treatments.

• Maximizing MSC Yield And Quality: A Comparative Media Study

  Maximize mesenchymal stem cell (MSC) expansion with a simplified culture process. New data demonstrates a high-performance, xeno-free media that eliminates the need for coatings or media exchanges.

• Expanding The Viscosity Limits Of Peristaltic Dosing

  Discover how innovations in closed-loop control and mechanical design extend peristaltic dosing limits to 2000 cP, maintaining accuracy while preserving the advantages of sterile, disposable paths.

• Multiplex Imaging

  Explore recombinant antibody reagents that support the imaging of key targets within the TME and offer flexible solutions across various platforms to improve patient outcomes.

• Control pH Adjustment And Reduce Complexity

  Learn how automated, banded pH control uses dose-and-wait logic to limit overshoot, account for mixing and buffer effects, and maintain stable setpoints across changing fill volumes.

• Alerion Microbubble Cell Separation System Used For T Cell Negative Selection

  Discover how the Alerion™ Microbubble Cell Separation System outperformed standard magnetic methods in T cell recovery, speed, and scalability — achieving higher cell quality with Akadeum’s innovative microbubble technology.

• Meeting Annex 1: A Proactive Approach To Regulatory Compliance

  It was imperative for a large European CMO producing multiple biologics to select the right product quality and value for each customer to comply with the August 2023 EU GMP Annex 1 revision.

• Filling Syringes With Spray-Dried Powders - The How, The Why And The Benefits

  Discover how filling spray-dried powders directly into syringes improves stability, minimizes cold chain reliance, and accelerates administration speeds for critical therapies.