CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Intuitive Bioprocess Scale-Up From Bench Scale To Pilot Scale

  This study explores scaling a high-demand fed-batch process from bench to pilot scale, highlighting control parameter differences at 50L and 500L while maintaining consistent growth and product titers.

• Comparing Sterility Testing Techniques

  Is your sterility testing process hindering your product release? Discover how the right approach can streamline your process, reduce false positives, and ultimately save you time and money.

• Why Choose Robotic Processing For Small Batch Aseptic Filling

  Reducing human intervention in aseptic filling is critical for safety and cost efficiency. Learn why automation is essential for small-batch applications and how it’s transforming sterile drug manufacturing.

• Simplify Process Scale-Up With An Innovative Single-Use Bioreactor

  Consistent cell growth and protein yields from 5 L to 5,000 L show how a unified bioreactor design can simplify scale-up, reduce risk, and accelerate upstream process development in bioproduction.

• Guide To Seeding, Expanding, And Harvesting Stem Cells

  Investigate important considerations for working with three different stem cell types: mesenchymal stem/stromal cells, induced pluripotent stem cells, and neural stem cells.

• The Application Of The Species-Specific Liver-Chip In Predicting Hepatoxicity

  An evaluation of 150 drug candidates causing adverse events in humans revealed testing in rats and dogs predicted only 71% of toxicities in humans. Discover a solution to this translational challenge.

• Revolutionizing Viral Infectious Disease Research And Drug Discovery

  Learn how Organ-Chips are being used to rapidly identify promising treatments, investigate virus evolution, and analyze how mechanical forces influence the innate immune response to viral infections.

• The Complete Flow Cytometry Guide

  This guide covers the fundamentals of flow cytometry, aiming to help you better understand how it works, when it is most valuable, and how to conduct an experiment.

• Streamline Your mAb Manufacturing With Strategic Development And CDMO Compatibility

  Though the journey to mAb development begins at lab scale, for clinical trials and commercial distribution, a production process must be streamlined and scalable to 2,000 L production and above.

• Large Scale Purification Of Oligonucleotides With IEX

  As oligonucleotide-based drugs gain momentum in therapeutic development, refining their manufacturing processes through solutions like ion exchange chromatography (IEX) becomes crucial.