CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• How A QMS Embeds Quality Into Cell Therapy Production

  Discover how a digital manufacturing solution helped a cellular therapy leader eliminate cleanroom paper, align quality teams, and accelerate batch release times by nearly 50%.

• Expansion Of Cord Blood-Derived CD34+ Cells In A Hollow-Fiber Bioreactor With 10% Standard Cytokine Concentration

  CD34+ cells isolated from cord blood were expanded in a hollow-fiber bioreactor using a novel cytokine cocktail at one-tenth the standard concentration using a MSC-free coating strategy.

• Challenges, Methods, And Solutions For Obtaining Optimal Starting Material

  For innovative treatments like CAR-T and stem cell transplants, optimal starting material is key. Understanding collection challenges and new solutions helps ensure the best foundation for these therapies.

• Enhance Access And Improve Retention In Rare Disease Trials With HTS

  Home Trial Support (HTS) provides a solution to improving participant recruitment and retention during musculoskeletal studies.

• Why RWD Strategy Can't Wait With Price, Value And Evidence Pressures Everywhere

  Overcome pricing pressures and reimbursement delays by integrating real-world evidence early in development to align clinical outcomes with payer demands and accelerate patient access.

• Enabling MSC Harvest, Wash, And Concentration

  A study demonstrates how a low-shear, closed-system centrifuge achieved over 90% MSC recovery and minimized viability loss, supporting scalable cell therapy manufacturing.

• Factors Influencing CD34+ Cell Collection Efficiency In Leukapheresis

  Efficiently collecting sufficient peripheral blood stem cells is paramount for successful transplantation, necessitating a deeper understanding of influencing factors and procedural nuances.

• Media Exchange In iPSC Cell Expansion And Differentiation: A Comparative Study

  Low-shear, closed-system media exchange in iPSC differentiation is vital for scalability. This study compares automated centrifugation to gravity sedimentation, showing equivalent or superior differentiation outcomes.

• Achieving Titer Increase Up To 4-Fold While Maintaining Product Quality

  Discover customizable solutions for antibody manufacturing, as well as services for media optimization, feeding strategy optimization, and format conversion.

• End-To-End Clinical, Biometrics, And Regulatory Support In Neurology

  Discover how an integrated NDA strategy aligned data, vendors, and regulatory execution to achieve an on-time submission and approval without major FDA queries.