CELL & GENE ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS

• Lentiviral Vector Upstream Process

  Scalable lentiviral vector production is moving beyond adherent systems. Learn how streamlined workflows enable linear scale-up in stirred-tank bioreactors for cost-effective gene therapy manufacturing.

• In Vivo RNA Tuning For Liver Gene Editing Efficiency

  RNA sequence and guide modifications, delivery platform design, and dose optimization all contribute to improved gene editing outcomes, which offers a clearer path toward safer, more potent, and scalable mRNA-based therapeutics.

• When To Consider Material And Personnel Airlocks For Downflow Booths

  Strategic use of airlocks in downflow booth design enhances pressure stability and containment. A risk-based approach ensures facility integration meets rigorous safety and compliance standards.

• Early Discovery Of Functional Antibody Leads

  Early functional screening accelerates therapeutic antibody discovery, improving hit rates and efficiency through advanced platforms like hybridoma upgrades, single B cell workflows, and tailored phage display strategies.

• From LAL To rFC: The Evolution Of Endotoxin Testing

  Protect patient safety and ensure regulatory compliance by implementing sensitive, reliable bacterial endotoxin testing as a critical component of pharmaceutical quality assurance.

• Navigating The Challenges Of Large, International Phase III Breast Cancer Trials

  In the competitive landscape of breast cancer research, aligning biomarker testing, regulatory pathways, and regional operations from day one creates a path to faster enrollment and stronger outcomes.

• Challenges, Methods, And Solutions For Obtaining Optimal Starting Material

  For innovative treatments like CAR-T and stem cell transplants, optimal starting material is key. Understanding collection challenges and new solutions helps ensure the best foundation for these therapies.

• Ensuring cGMP Compliance In Cell And Gene Therapy Manufacturing

  Discover how adhering to strict GMP guidelines and advanced equipment design ensures that complex, sterile cell and gene therapies are safely and effectively delivered.

• Biopharma Production And Quality Control With Electrophoresis

  Discover how Kaneka Eurogentec, a leading provider of custom DNA synthesis and molecular biology services, enhanced their fragment analysis to achieve higher efficiency and accuracy in their workflows.

• Development Strategies For Adenovirus-Based Gene Therapies

  Scaling up viral vector production can be challenging, and ensuring consistent titers and activity requires careful optimization and technical expertise.