Cell And Gene Articles, App Notes, Case Studies, & White Papers

1. Simplifying The Transition To Multi-Column Chromatography 4/5/2024

   Explore the advantages of multi-column chromatography and how to transfer your process from batch to an intensified system, step-by-step.

2. Optimized Performance Model For Yield And Quality Of The mRNA Product 4/9/2024

   Optimize your mRNA production by identifying an optimum set of conditions for the IVT reaction that produces high-quality mRNA in high yield using a design of experiment (DoE) approach.

3. Lyophilization To Enable Drug Products Containing Labile Molecules 6/6/2025

   Develop lyophilized formulations to overcome stability challenges and significantly extend the shelf life of sensitive therapeutic products.

4. High-Throughput 90-Minute ELISA 9/17/2024

   Discover how one solution can be utilized to measure Human IgG and human IFN gamma, which are key targets in pharmacokinetic studies and immunotherapeutic drug safety testing, in just 90 minutes.

5. Electroporation Enables Efficient Antibody Discovery By Mammalian Display 11/22/2024

   Therapeutic antibody developers leverage mammalian display to identify promising candidates. Electroporation enables superior sequence diversity, enhanced library coverage, and streamlined workflows.

6. Natural Killer Cell Expansion And Scale-Up In Vertical-Wheel Bioreactors 12/18/2024

   Allogeneic Natural Killer (NK) cell therapy offers a promising avenue for cancer immunotherapy. However, traditional platforms struggle to achieve the scalability required for clinical translation and commercial manufacturing.

7. Phase-Appropriate Approaches To Manufacturing And Testing 3/14/2025

   Accelerate the development of high-quality biopharmaceuticals by implementing phase-appropriate, risk-based manufacturing and testing strategies that ensure timely progression.

8. 5 Essential Capabilities For Decentralized Clinical Trials 2/3/2025

   Learn how to develop and utilize a successful DCT framework, enabling your study to enhance patient access, improve data quality, and streamline study operations.

9. How Lipid Nanoparticles Enable Next-Gen Delivery 10/20/2025

   Cell therapy’s future depends on smarter gene delivery. Learn how lipid nanoparticles offer a scalable, cell-friendly alternative to electroporation and viral vectors for manufacturing efficiency.

10. Maximizing Scale-Up Efficiency Of A mAb Upstream Process 6/17/2024

    This study demonstrated the effectiveness of a medium and feed system when tested at three different scales for its ability to high-quality, fed-batch monoclonal antibodies.