Cell And Gene Articles, App Notes, Case Studies, & White Papers

1. What Provided Critical Reagents to the COVID-19 Pandemic Response? 4/28/2023

   Typically, monoclonal antibody (mAb) manufacturing takes up to 60 days due to demand and outsourcing lags. Instead, imagine a unified platform that can deliver your mAb in 18 days.

2. Dispensing Fungal Spores 10/11/2022

   Learn how this single cell dispenser was used to sort and isolate individual, fluorescently labeled germinating fungal spores among non-germinating spores.

3. How Syringe Filtration With Integrated Prefilter Technology Improves HPLC Performance And Throughput 4/29/2022

   In this article we review how particulate removal through filtration effects column life and how to handle difficult to filter samples.

4. Why More Drugs Than Ever Are Approved Through 505(b)(2) 6/6/2022

   Discover how bringing a modified version of an existing drug to market through 505(b)(2) can offer a clear path to approval, a differentiated product, and at least some period of marketing exclusivity.

5. Fast, Reproducible AAV Vector Quantification With Simple Plex Assays 11/2/2022

   Explore an effective automated analytical solution that could lead to increasing your facility's throughput during the viral quantification process.

6. Lentiviral Vector Analysis For Cell And Gene Therapy Made Simple 6/3/2022

   Explore a capillary electrophoresis immunodetection platform that allows you to measure lentiviral vector identity, titer, stability, purity, capsid content, and transduction efficiency, all in one instrument.

7. Leveraging Clinical Trial Data In Real Time To Effect Change And Mitigate Risk 1/19/2022

   Learn how clinical trial data gathering, contextualization, and analysis can all benefit from existing — but underutilized — technologies and resources.

8. Beyond The Process: Important Factors For Long-Term Biomanufacturing Success 10/22/2021

   For long-term manufacturing success, you need to look beyond the process and account for an amalgamation of many important factors. Your process will go through many different phases, and it needs to be scalable throughout, or you will incur additional challenges and costs.

9. Improving Expression And Purification Of mAb 2/8/2022

   To achieve high transient protein yields, TGE is dependent on an efficient transfection method. We review a system for optimal protein production in several commercially available suspension CHO cell lines.

10. Optimizing Recovery On The Sepax™ Cell Processing System 7/21/2022

    Using a model T-cell line, we demonstrate the impact of varying rinse volume, intermediate volume, and manual extraction parameters on overall cell recovery with a final product dose volume of 20 mL.