Cell And Gene Articles, App Notes, Case Studies, & White Papers

1. Challenges And Solution In The Poly (A) Control For Plasmid And mRNA 11/25/2025

   Poly(A) tail integrity is critical for mRNA stability and translation. Advanced strategies optimize plasmid design, transcription, and purification to ensure consistent poly(A) control for therapeutic success.

2. Digital Standardization: Accelerating Gene Therapy Tech Transfer With Confidence And Compliance 4/1/2026

   Fragmented, manual data practices slow tech transfer and increase risk; centralized digital CMC systems standardize workflows, improve transparency, and accelerate onboarding while maintaining compliance.

3. Efficient Late-Stage Development Of Biologics 11/25/2025

   Reducing biologics manufacturing costs requires strategic late-stage process development, yield optimization, scale-up, and raw material substitution—all while maintaining product quality and regulatory compliance.

4. Anaerobic Cultivation Processes Of Probiotic Bacteria 12/18/2025

   Cultivate oxygen-sensitive probiotics with precision using real-time monitoring, microfluidic feeding, and pH control for reproducible growth and optimized microbiome and fermentation research.

5. Expert Insights In Navigating CGT's Complex Supply Chain 10/30/2024

   Examine insights shared during Cencora's ThinkLive Cell and Gene Therapy Summit 2024 that shed light on the challenges and opportunities in navigating the complexities of the cell and gene supply chain.

6. Targeted LC-MS/MS Detection Of Lipid Impurities In Lipid Nanoparticles 12/9/2024

   Learn about an HPLC-MS/MS method for detecting lipid impurities in lipid nanoparticles (LNPs) and why it is critical for quality control of LNP-based drug delivery systems.

7. Navigating Project Optimus And The Rapidly Changing Oncology Development Landscape 9/1/2025

   Project Optimus and adaptive trial designs are reshaping oncology development, improving patient outcomes, and streamlining approval pathways.

8. In Vivo RNA Tuning For Liver Gene Editing Efficiency 10/28/2025

   RNA sequence and guide modifications, delivery platform design, and dose optimization all contribute to improved gene editing outcomes, which offers a clearer path toward safer, more potent, and scalable mRNA-based therapeutics.

9. Biocompatibility Studies On CHO Cell Culture In X-ray Irradiated BioBLU® Single-Use Bioreactors 9/5/2024

   In cell culture, the leakage of toxic or inhibitory chemicals from single-use bioreactors has become a growing concern. Explore recommendations for leachable studies.

10. Assessing Viability And Real-Time Apoptosis/Necrosis 3/17/2025

    Malignant gliomas are aggressive brain tumors that resist standard treatments. Discover why researchers focus on real-time cell death dynamics to develop targeted therapies and promising strategies.