Cell And Gene Articles, App Notes, Case Studies, & White Papers

1. Pioneering Gene Therapy In Rare Diseases 3/17/2025

   Overcoming barriers to gene therapy development requires continued innovation in manufacturing processes, harmonized regulatory approaches, and outcome-based pricing models.

2. mRNA Purification Using Anion Exchange Chromatography At Ambient Temperature 12/11/2024

   Explore how anion exchange chromatography with dual gradient elution enables efficient mRNA purification at ambient temperature.

3. CDMO Accelerates Contract Manufacturing With Electronic Batch Records 9/18/2024

   A prominent CDMO sought a specialized software solution to streamline and accelerate its manufacturing processes, enabling the efficient production of complex, customized products in record time.

4. Advancing Oncology Innovation With Adaptive Trial Designs 8/12/2025

   When a biopharmaceutical company developing a novel therapy for solid tumor cancers became concerned with rapid over-enrollment from within a single region, they employed a CRO for assistance.

5. Relieving The Strain Of Publishing During Regulatory Registration 8/7/2024

   Go inside how an expertly handled NDA submission for a biopharma company ensured timely FDA approval despite challenges.

6. Epigenetics Application Guide: RNA Modifications 9/26/2024

   Learn about the rapidly evolving field of RNA modifications, including innovative techniques like miCLIP and RIP for mapping chemical modifications and understanding RNA’s role in cellular processes.

7. Development Of Allogeneic CAR T Cells As A Potential Therapy For Acute Myeloid Leukemia 2/21/2025

   Discover how enabled development of allogeneic CAR T-cells offers a promising, off-the-shelf therapy approach for acute myeloid leukemia.

8. Development And Optimization Of LNP Formulations 12/6/2024

   The production of lipid nanoparticles (LNPs) is a process that demands robustness, scalability, and reproducibility. Examine the impact of key operational parameters on the efficacy of LNPs.

9. Best Practices For Oncolytic Virus Design, Development, Manufacturing 3/12/2025

   Oncolytic viruses have the potential to revolutionize standard cancer treatment, but their continued progress hinges on meeting a number of goals linked to safety, efficacy, and commercial scale-up.

10. Tackling CGT Challenges: Stirred-Tank Bioreactors For R&D And Commercial Manufacturing 7/8/2025

    Scalability remains a key bottleneck in CGT manufacturing. See how optimized stirred-tank bioreactor systems accelerate translation from clinical to commercial production.