Cell And Gene Articles, App Notes, Case Studies, & White Papers

1. Integrated Upstream And Downstream Strategies For Robust mAb Manufacturing 2/5/2026

   Process robust mAb production requires understanding scale dependent cell environments, leveraging predictive models, and pursuing data driven control to minimize variability, optimize quality, and ensure reliable technology transfer across biomanufacturing scales.

2. 3D Neurospheres In Healthy And Alzheimer's: iPSC-Derived Neurons 4/4/2025

   Explore how different ApoE alleles influence Alzheimer's Disease risk using iPSC-derived neurons as well as gain insights into AD mechanisms and potential therapies.

3. Efficient Late-Stage Development Of Biologics 11/25/2025

   Reducing biologics manufacturing costs requires strategic late-stage process development, yield optimization, scale-up, and raw material substitution—all while maintaining product quality and regulatory compliance.

4. Optimizing Performance For De-Risked Lentiviral Vector Production 6/12/2024

   Discover a de-risked, reproducible, and scalable platform for efficient GMP manufacturing of lentiviral vectors that maximizes titers and enriches recovery through upstream and downstream optimization.

5. Make Your Production Sites Adaptable And More Efficient 12/12/2025

   Pharma faces mounting complexity and tighter margins, demanding agile, future-ready production. Discover how smart manufacturing enables faster adaptation and continuous therapy availability.

6. Application Of A Dual Spiking Strategy In Viral Clearance Studies 2/3/2026

   Explore how an alternative spiking strategy can streamline viral clearance studies, reduce material demands, and maintain compliance while addressing the challenges posed by MLV and MMV.

7. Buffers And Process Liquids For Biopharmaceutical Production: Considerations For Scale-Up And Outsourcing 5/7/2024

   For small and midsize biopharmaceutical organizations, outsourcing buffer and process liquid preparation, quality testing, and storage could significantly streamline operations and reduce regulatory risk.

8. Bulk Filling Of Drug Substance | Accurate Aliquoting 4/24/2024

   Bulk filling drug substances in traditional facilities is often a lengthy, manual process where operators are relied upon to adjust pump controls to achieve accurate filling. This method, spanning multiple shifts, increases process risk through errors that can compromise accuracy.

9. Pave The Way To High Productivity With Continuous Manufacturing For Pharma 12/12/2025

   Continuous manufacturing delivers agility and precision for pharma, combining automation, reduced manual steps, and quality control to meet regulatory and cost pressures while accelerating development.

10. A Duplex Assay For Quantification And Qualification Of AAV 5/13/2025

    Adeno-associated virus is a key gene therapy vector. Explore how digital PCR offers precise, standard-free quantification with improved consistency and inhibitor tolerance over traditional qPCR methods.