Cell And Gene Articles, App Notes, Case Studies, & White Papers

  1. Upscaling hMSC Production Enhances Extracellular Vesicle Secretion And Cargo Profile 12/19/2024

    Explore how the dynamic microenvironment of bioreactors influences the production and composition of extracellular vesicles (EVs), including exosomes, secreted by human mesenchymal stromal cells (hMSCs).

  2. Advancing Cell Therapy Manufacturing: Rapid Sterility Testing 5/7/2024

    The rapid sterility test kit used in the study was able to quickly detect bacteria and fungi in complex cell therapy product matrices, detecting six species listed in USP chapter <71>.

  3. Testing Cell-Based Immunotherapeutics For Microbial Contaminants 10/23/2023

    In this study, two different immune cell preparations were evaluated for their compatibility with the Milliflex® Rapid System to establish a USP and EP compliant method for rapid sterility testing.

  4. Determination Of Immune Cell Composition And CAR-T Cells 3/28/2025

    Discover a system that automates CAR-T cell production using flow cytometry and analyzers for precise monitoring as well as learn about the sample preparation, instrument setup, and data analysis.

  5. Physiologix Serum Replacement Performance On T Cells 9/16/2024

    A serum replacement for promoting T cell growth and functionality in cell therapy development shows comparable or superior performance to traditional human serum supplements.

  6. Overcoming Scale-Up Challenges In iPSC Production: A Joint Investigation 6/26/2025

    Discover how new processing methods tackle challenges in large-scale stem cell production. Learn how automated, low-shear processing maintains cell health and pluripotency across various production scales.

  7. A Guide To Adherent Scale-Up 9/5/2023

    Biomanufacturers looking to take advantage of the ongoing biomedical revolution and new treatments can benefit from platform solutions utilized in scaling-up adherent cell cultures.

  8. Pre-Launch Checklist - A Roadmap To Success 6/21/2024

    The path from groundbreaking therapy to readily available treatment requires a strategic approach. Delve into ten critical questions that can help you chart a successful course for your CGT therapy.

  9. Use Of 60 Micron Plastic (PE) Retention Filter For Perfusion Media Exchange 2/3/2025

    Explore guidance on the materials and methods recommended for assembling a perfusion system using a 60 Micron Plastic (PE) Retention Filter with a Vertical-Wheel Bioreactor.

  10. Oncolytic Virus Therapies – Global Clinical Trial Landscape - Focus On Asia Pacific 9/11/2023

    Explore the global landscape of oncolytic virus clinical trials, with a particular focus on trends in the Asia Pacific region.