Cell And Gene Articles, App Notes, Case Studies, & White Papers

1. Understanding Potency In Gene Therapy Development 2/28/2024

   Explore the importance of understanding potency in cell and gene therapy (CGT) development and the challenges in developing potency assays for CGT products.

2. AI-Enabled Phenotypic Analysis Of Label-Free Intestinal Organoids 3/10/2025

   Discover how advanced 3D models and AI-enabled imaging techniques revolutionize organoid research, which provides accurate phenotypic analysis to monitor growth and development in various organoid types.

3. Purity Analysis Methods For Synthetic Prime Editing Guide RNAs 9/8/2023

   Develop a fast, easy workflow for the purity analysis of complex pegRNA molecules along with a robust denaturing technique for pegRNA with high levels of secondary structure.

4. Monitoring Microbial Contamination Of Mammalian Cell Cultures 2/21/2025

   Mammalian cells are widely used to produce complex processed molecules. Explore a system that effectively detects microbial contamination in mammalian cell cultures and utilizes a newly formulated lysis buffer.

5. Accelerating The Development And Optimization Of Cell Culture Media 10/18/2024

   Here, we outline the use of a microbioreactor for the rapid screening and optimization of media formulations for perfusion processes, and its role in predicting the performance of larger-scale bioreactors.

6. Continuous Monitoring And Control Of Glucose And Lactate 5/22/2024

   This experiment demonstrates that continuous real-time monitoring of glucose and lactate and dynamic glucose feed control to a low-level set-point leads to improved process and product parameters.

7. Ensuring cGMP Compliance In Cell And Gene Therapy Manufacturing 6/16/2025

   Discover how adhering to strict GMP guidelines and advanced equipment design ensures that complex, sterile cell and gene therapies are safely and effectively delivered.

8. Screening Peptones, Including "Titration And Blending" Protocol Examples 5/3/2024

   Dive into the importance of peptone selection, instructions for reconstituting peptone powders for mammalian cell culture, and discover starter packs containing commonly used peptones for specific applications.

9. Mobile Gowning Cleanroom, Built To Meet ISO 7 Requirements 6/19/2024

   Uncover how Germfree designed and installed a mobile cGMP cleanroom on a 53′ tractor-trailer chassis to provide a flexible and efficient cleanroom solution tailored to the company’s needs.

10. Understand Fluorescence And How It Enhances Scientific Exploration 9/24/2024

    Deepen your understanding of fluorescence for research, and gain valuable insight into how to select appropriate fluorophores and fluorescent proteins for your experiments.