Cell And Gene Articles, App Notes, Case Studies, & White Papers

  1. Real-Time And In-Line Raman Spectroscopy For Glycan Quality Analysis 6/14/2024

    This study details the use of in-line Raman spectroscopy to monitor mAb glycan profiles within a production bioreactor, highlighting its potential for automation and customization.

  2. A Scalable Manufacturing Platform For The Purification Of Stem Cell Derived Exosomes 5/16/2025

    EV production scale increases require paired robust, scalable, and cost-effective downstream processes. Process parameters can be tailored for therapeutic exosome programs and allow for maximum exosome recovery.

  3. Optimizing Human iPSC Aggregate And Organoid Production For Bioprinting 4/17/2024

    This study aimed to identify the optimal cell culture conditions to yield high cell density and maintain high cell viability with consistent aggregate morphology and pluripotency marker expression.

  4. Supporting A Rapidly Growing Biotech With A Unique Ocular Gene Therapy 2/12/2025

    An emerging biotech developing a viral vector-based gene therapy needed a flexible and experienced partner to navigate the complex transition from preclinical studies to first-in-human trials.

  5. Real-Time PCR And Gene Expression Specificity 3/27/2025

    Gene expression analysis requires high specificity to ensure accurate results. Methods like probe-based assays offer greater specificity than dye-based detection.

  6. Developing A Large-Scale Tangential Flow Filtration Process 5/13/2024

    Discover a process that can be modified to fit your downstream process and serves as a complete solution for concentration and diafiltration.

  7. Prevent The Risk Of Cross-Contamination With Microbial Colony Pickers 3/17/2025

    Explore a microbial colony picker that streamlines lab workflows to ensure rapid and accurate genetic library screening. Key features include UV sanitization, pin washing, and halogen drying, which meets GMP standards.

  8. 3D Neurospheres In Healthy And Alzheimer's: iPSC-Derived Neurons 4/4/2025

    Explore how different ApoE alleles influence Alzheimer's Disease risk using iPSC-derived neurons as well as gain insights into AD mechanisms and potential therapies.

  9. Comparison To And Advantages Over Traditional Chemometrics Models 4/5/2024

    As Raman spectroscopy, with partial least squares (PLS) models, becomes more popular in bioprocesses applications it's important to recognize the challenges this approach presents.

  10. Generation Of Stable CHO Cell Lines For Protein Production 3/22/2024

    By following the five steps of a specialized protocol, exceptional yields and stable cell lines can be achieved in CHO cells using antibiotic selection.