Cell And Gene Articles, App Notes, Case Studies, & White Papers
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Remote Access And Monitoring Of Bioprocess Unit Operations
5/26/2022
Digital transformation projects require a scalable connectivity solution for the manufacturing floor that is easily and rapidly deployed. Explore elements that enable connectivity among equipment.
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From Bench To Billions: Facilitating Scale-Up Of Adherent Cultures For Cell And Gene Therapies
6/27/2022
We review what researchers should consider when they are creating a risk-mitigating adherent culture process for cell and gene therapy scale-up.
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Exosome Isolation By TFF And Size Exclusion Chromatography
3/6/2024
Here, we demonstrate a scalable workflow for the isolation of exosomes that combines tangential flow filtration for the concentration of exosomes followed by gentle size exclusion chromatography.
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Expansion Of Porcine SK-RST Cells On Microcarriers Via Serial Passage In Stirred Vessels
9/7/2022
By performing a small-scale study with multiple microcarrier types and medias we identify the best microcarrier and media for the expansion of porcine SK-RST cells via microcarrier-based serial passage in stirred vessels.
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Optimizing And Intensifying ADC Aggregate Removal With A DoE Approach
11/29/2023
This study explores the feasibility of using single-use chromatography membrane technology as an alternative to resin-based chromatography in an ADC process.
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Development And Optimization Of Suspension-Adapted 293T Cell Line
3/21/2024
Learn how an adapted cell line can reduce costs and improve scalability in the production of lentiviral vectors for CGTs and examine its potential to produce GMP-grade lentiviral vectors.
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Optimizing Lipid Formulations For Targeted RNA-LNP Applications
9/13/2022
Learn about the considerations and challenges of using ionizable lipids, including the 5 types of lipids used for RNA delivery.
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Enrichment Of High Titer CHO Cells
10/11/2022
Learn how this single cell dispenser was used to isolate high titer CHO cells by dispensing an enriched pool of fluorescently tagged high producers.
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CD56 Cell Depletion From PBMCs Applied To Validate A HIV-Specific ADCC Mechanism
5/4/2023
Explore results from a study that utilized an in vivo model to assess the antibody-dependent cellular cytotoxicity (ADCC) activity of antibodies to clear HIV-infected cells.
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Testing Cell-Based Immunotherapeutics For Microbial Contaminants
10/23/2023
In this study, two different immune cell preparations were evaluated for their compatibility with the Milliflex® Rapid System to establish a USP and EP compliant method for rapid sterility testing.