Cell And Gene Articles, App Notes, Case Studies, & White Papers

  1. Scalability From 5L To 50L Using The DynaDrive Single-Use Bioreactor 8/14/2025

    Maintaining a consistent bioprocess when scaling from 5 L to 50 L is achievable. This study shows how to successfully scale processes while maintaining cell density, viability, and protein production.

  2. Scale-Up Approaches For Culturing Adherent Cells 3/5/2025

    For successful scale-up, see how optimizing process parameters such as attachment methods, gassing, and agitation can help reduce cell environmental stress, ultimately improving productivity.

  3. Accelerate Process Development With Automated Aseptic Sampling 5/6/2024

    Discover how implementing automated sampling systems enabled Takeda Pharmaceuticals to achieve new efficiencies in process development.

  4. Tackling CGT Challenges: Stirred-Tank Bioreactors For R&D And Commercial Manufacturing 7/8/2025

    Scalability remains a key bottleneck in CGT manufacturing. See how optimized stirred-tank bioreactor systems accelerate translation from clinical to commercial production.

  5. Proof-Of-Concept Study Enabled To Drive Novel Gene Therapy Program 9/29/2023

    Unearth how a natural history trial aimed at addressing the exceptionally rare neurological disease affecting pediatric patients with no existing treatment options was executed successfully.

  6. Next-Generation CRISPR Approaches 7/16/2024

    By providing essential components like nucleases, gRNAs, and HDR templates, a reliable CDMO facilitates a seamless transition from discovery research to clinical trials and beyond.

  7. Background-Free Analysis Of Mouse TILs 3/28/2025

    Syngeneic mouse tumor models are crucial for immunotherapy research, but variability in TILs and nonspecific binding complicate analysis. Discover how blocking reagents help but make the process more labor-intensive.

  8. High Yield Protein Production System For Suspension CHO Cells 3/22/2024

    Reduced the risk of contamination caused by repeated handling of the culture during transient protein production in suspension CHO cells.

  9. Integrated And Connected Downstream Processing Of mAbs 2/21/2024

    We describe how intensifying two chromatography polishing steps by developing unit operations using Sartobind® Q and CMM HyperCel saves buffer volumes and accelerates the downstream process.

  10. AAV Vectors In Gene Therapy Clinical Trials 4/16/2025

    AAV-based gene therapies show promise but face immune challenges. ELISpot assays help evaluate T cell responses, enhancing clinical trial design and improving therapeutic success.