Thermo Fisher Scientific

ABOUT THERMO FISHER SCIENTIFIC

Thermo Fisher Scientific is a leading global provider of cell and gene therapy development solutions. We accelerate your novel therapeutics from clinical development to commercialization. With our comprehensive portfolio of products and services we will be your dedicated partner throughout the development journey.

Key Capabilities:

Plasmid construction, vector production, and purification
Cell isolation, engineering, expansion
Lot release, characterization, and preservation
Formulation, fill, and finish
Expert professional support to meet process, scale, quality, and regulatory requirement

WEBINARS AND VIDEOS

Achieving High Purity In Complex Antibody Formats

Discover innovative purification strategies and workflow designs for next-generation antibody formats and learn to overcome challenges in achieving high purity and yield.
Enhancing Protein Quality Through Optimized Galactosylation

Advance your understanding of critical protein engineering. Explore expert strategies for optimizing complex molecular structures, paving the way for more effective and consistent biological products.
Global Strategies For Resilience And Redundancy In Cell Culture Media Supply

Ensure your cell culture media supply remains uninterrupted. Explore proactive strategies for global manufacturing equivalency and consistent media delivery.
Tackling Residual DNA Testing In Biotherapy Manufacturing

Controlling residual host cell DNA is critical for the safety and efficacy of biotherapeutics. Learn about robust, highly sensitive analytical methods for effective DNA clearance and process control.
Expanding Manufacturing Of Purification Resins To Align With Customer Demands

Discover how scaling up processes and building out facilities has allowed for end-to-end solutions that meet customer requirements for both supply and quality in their production lines.
Ensuring Quality, Driving Customer Confidence

How does quality assurance help drive scientific progress? A 30-year veteran shares her story of supporting customer needs and the development of groundbreaking new therapeutics.
An Innovative Approach To High Aggregate Challenges

In this webinar, hear from a technical specialist on addressing the challenges with antibody aggregates and process related impurity removal using a new high performance chromatography resins
Enhancing Aseptic Fill-Finish Processes

Achieve exceptional product recovery and sterility. Learn about high-integrity surge bags, advanced leak detection, and flexible design options for your fill-finish applications.
CAR-T Innovation: Balancing Allogeneic And Autologous Cell Therapy

Join experts as they discuss strategies for optimizing allogeneic and autologous therapies, aiming for balanced development and wider patient accessibility by 2030.
Efficient AAV Purification With AAVx And AAV9 Magnetic Beads

Explore an alternative to chromatographic affinity capture that eliminates the need for universal nuclease treatment by utilizing magnetic beads with ligands specific to AAV.
Efficient-Pro Medium And Feed (Why Choose Pro)

Discover an animal-origin-free and chemically defined medium and feed system solution designed to revolutionize your workflow.
Leveraging Rapid Sterility Testing To Advance Cell Therapy Production

Explore the crucial role of rapid sterility testing in cell therapy manufacturing. This presentation delves into the benefits of swift, accurate detection for product quality and patient safety.
Supporting Efficacy And Scaling With A Next-Generation T Cell AOF Formulation Medium

Explore a novel, next-generation medium designed with an animal component-free formulation to boost therapeutic potential and enable reproducible T cells.
Development Of A CHO Medium And Feed System Using Advanced Analytical Tools And Workflow Considerations

Discover how a new, chemically defined cell culture medium and feed system can maximize recombinant protein production in Chinese hamster ovary (CHO) cells, enhancing productivity and streamlining manufacturing.
Microbial Identification Via DNA-Seq

Learn how DNA sequencing-based microbial identification supports regulatory compliance and enhances contamination control in critical environments.
BPI Interviews Purification And Pharma Analytics Leader

Jean Luo, VP of Purification and Pharma Analytics, discusses innovations in bioprocessing, including the development of dPCR assays, lentiviral titer systems, chromatography resins, and supply chain.
CTS DynaCellect Fluidics Demonstration

Streamline and customize your cell processing workflow with automated, precise control over fluid movement and transfer parameters.
Advancing The Purification Of VSV-G Pseudotyped Lentiviral Vector

Discover new strategies to overcome lentiviral purification challenges with a scalable approach that maintains viral infectivity through gentle processing conditions.
AAV Purification: Solving Downstream Challenges

In this roundtable discussion, a trio of distinguished experts in AAV purification and process development share their expertise and best practices in tackling and solving downstream challenges.
Knowledge Culture Basics — Gene Therapy Education Series: Lentiviral Vectors

In this session of our ongoing education series on lentiviral vectors, we delve further into principles of lentiviral transduction and challenges in suspension-based lentivirus production.
Validation Of A qPCR Assay For Host Cell DNA Quantitation

Here, we share the development and validation of a new, highly sensitive and accurate integrated solution for detection and quantitation of host cell DNA to help meet regulatory requirements.
Uninstalling CTS Dynacellect Bead Removal Kit

A detailed walkthrough on how to uninstall the Gibco CTS DynaCellect Bead Removal Kit when the bead removal protocol or the Gibco CTS DynaCellect magnetic separation system is completed.
Advances In Microbial Fermentation Knowledge Culture

Presented by three experts, this session examines real-world examples of how different approaches to media formulation and process conditions can influence outcomes.
Advanced Contamination Control: Automation, Assays, Process Efficiency

Learn how automated closed systems and larger bioprocess containers contribute to maintaining product integrity and how rapid analytical assays can offer reliable and accurate contamination detection.
Knowledge Culture: Downstream Innovation

In this workshop, you’ll learn about various solutions, from cell isolation to cell expansion, that can support autologous and allogeneic cell therapy process needs, digital automation, and mycoplasma testing.
Isolating CD4 / CD8 T Cells For Improved Drug Efficacy, Productivity

Learn how the active detachment of dynabeads from target cells at any time allows users to add flexibility and scalability to their process.
Peptones And Vaccines: A Synergistic Approach To Enhanced Production And Efficiency

Enhance your vaccine manufacturing with peptones. Explore their benefits, analyze data-driven productivity gains, and learn integration strategies in this informative, on-demand session.
BioTitan Retention Device Overview

Learn about a retention device that provides robust fortification for single-use assemblies. Its 360-degree seal strengthens connections, reduces leak risks, and ensures process integrity for fluid transfer.
Maximize Your Drug Product Recovery With A Complete Fill Finish Solution

Discover how to maximize drug product recovery with an end-to-end fill-finish solution. Get excellent integrity assurance and exceptional lead times for your critical processes.
Building A Purification Toolkit For An Expanding Variety Of mAb Therapeutics

Explore techniques for optimizing purification toolkits for various monoclonal antibody formats. This session covers resin and buffer selection for efficient downstream process development.
Cell Therapy Bioprocessing Workflow Cinematic

Witness a seamless cell therapy bioprocessing workflow that reduces manufacturing time and preserves the crucial cell phenotype for scalable, effective autologous and allogeneic therapies.
Implementing Rapid Microbial Identification In Biotherapy Manufacutring

Learn about rapid microbial identification strategies that enhance environmental monitoring and compliance with regulatory requirements for your manufacturing processes.
Ultralow Particulate Bottles And Carboys: Where Being Particular About Particulates Is Critical

Optimize your operations with ready-to-use, meticulously prepared containers. Learn how our commitment to cleanliness reduces risks and supports your most critical requirements.
Setup Made Simple With The BioTitan Retention Device

Find out how quick and simple it is to set up an assembly secured with the Thermo Scientific BioTitan Retention Device.
Successful Microbial Testing And Identification

In this presentation, one of our industry-leading customers discusses how they've successfully implemented the Applied Biosystems MicroSEQ Microbial Identification System in their laboratory testing.
Advances In Flow-Through Technology To Enhance mAb Polishing

Walk through three case studies that illustrate how novel chromatographic tools can improve the purification process for complex therapeutics by reducing aggregates and HCPs and effectively clearing retroviruses.
ResDNASEQ Workflow Solution

Overview of the resDNASEQ workflow solution.
Innovations In Mycoplasma And Sterility Testing For Biopharma

In this webinar, our expert speakers will discuss the types of analytical testing that can be effectively employed in the early stages of therapeutic development and subsequently scaled to meet production challenges.
CTS DynaCellect Magnetic Separation System Cell Isolation

Ready to achieve high-purity results in your cell therapy manufacturing? This step-by-step guide demonstrates the complete setup and installation for your automated magnetic cell isolation system and kit.
CTS OpTmizer One SFM: Thoughtfully Designed Nutrition For T Cells

Learn about a novel, next-generation medium with an animal-component-free formulation developed to support the need for a T-cell medium that allows consistent, reproducible, and automated T-cell manufacturing.
An All-In-One Solution For Residual DNA Quantitation

Explore an all-in-one solution for residual DNA quantitation with a 3D lab tour with virtual demos, videos, and interactive instrument guides to experience the full workflow.
Maximizing Media Strategies: Expert Insights On Boosting Performance

Optimize biopharma media strategies for consistent protein quality. Experts discuss formats, variability, and actionable analytics in this on-demand virtual roundtable.
A Robust, Future-Ready Solution That Adapts To Your Needs

Explore a future-ready solution that features advanced automation, intuitive design, and scalable solutions to streamline your bioprocessing workflows and prepare your operations for future growth.
AAV Downstream Challenges: Expert Insights

Gain expert insight into the complexities of AAV purification to learn how industry leaders tackle downstream challenges, optimize workflows, and drive innovation in scalable, efficient gene therapy manufacturing solutions.
Rethinking Sustainability In Bioprocessing

Discover how sustainability is transforming bioprocessing through innovative single-use technologies that help reduce environmental impact and support responsible, forward-thinking biomanufacturing.
Innovative Strategies For Residual DNA And Viral Titre Quantitation

Discover how digital PCR improves the accuracy of residual host cell DNA and viral titre quantification in biotherapeutic manufacturing to enhance product quality, safety, and regulatory compliance.
Enhanced Chromatography Resins For Faster, More Efficient Purification

Learn from an industry veteran about the evolution of protein purification, from early equipment to modern, agile solutions, emphasizing continuous improvement and customer-centric approaches.
Tailoring Purification Solutions To Address Customer Challenges

Developing purification products for novel biotherapeutics requires close customer collaboration to ensure the tools do the job. Hear how these partnerships drive targeted innovation.
Solutions For Diverse Biomolecule Purification

Interview with Paul Lynch, Product Management Leader, Purification, discusses our chromatography resins and innovations in downstream purification processes.
Fast Track Your Path To Commercialization

Discover key strategies for scaling biologics from bench to pilot scale and learn how to overcome challenges in process development, including control of agitation, oxygen, CO₂, and nutrient supplementation.

CONTACT INFORMATION

Thermo Fisher Scientific Bioproduction

7305 Executive Way

Frederick, MD 21704

UNITED STATES

Contact: Hunter Tuck

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BROCHURES

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FEATURED ARTICLES

Consistent Improvement In CHO-K1 GS Performance With Efficient-Pro Feed 3 And Efficient-Pro Feed Enhancer

Optimize your CHO-K1 GS cell line with advanced chemically defined, animal origin-free feeds. Achieve higher titers and reliable product quality.
The Value Of Peptones For Cost-Effective Vaccine Manufacturing

Peptones offer a strategic solution to key biomanufacturing challenges by enhancing cell culture performance, improving yields, and reducing production costs.
Improved T Cell Expansion Using Closed, Automated Stirred-Tank Bioreactors

A shift from traditional rocking motion systems to stirred-tank bioreactors can enhance T cell expansion, offering greater scalability and more intimate process control.
Comparing Serum-free To Serum-Supplemented Media

Reducing serum in vaccine manufacturing is a key consideration for lowering costs and improving supply security. We compare performance in serum-free versus serum-supplemented media.
A Temperature-Stable Replacement For Animal Trypsin In Cell Dissociation Applications

Improve cell dissociation with a gentle, recombinant enzyme. This temperature-stable protease shows dissociation kinetics similar to porcine trypsin but with lower cell toxicity and greater overall purity.
Streamline Your mAb Manufacturing With Strategic Development And CDMO Compatibility

Though the journey to mAb development begins at lab scale, for clinical trials and commercial distribution, a production process must be streamlined and scalable to 2,000 L production and above.
The Role Of Peptones In Boosting Monoclonal Antibody Production

Peptones have become a key tool in CHO cell bioprocessing, enhancing monoclonal antibody yield and quality.
Optimize Your Approach To mAb Development

To meet the growing demand for mAbs and their variants, it is important to leverage opportunities for optimization as well as work with suppliers that have the resources to help your workflow thrive.
Finding An Optimal Harvest Solution By Considering Both Cost And Sustainability

Optimize your bioprocessing harvest with single-use centrifugation. Reduce costs, waste, and space needs compared to traditional depth filtration methods.
Single-Use Technology And Environmental Responsibility In Biopharmaceuticals

Learn about strategies such as regional manufacturing and advanced single-use systems and their potential to minimize carbon footprint and enhance sustainable biomanufacturing.
Scale-Up Approaches For Culturing Adherent Cells

For successful scale-up, see how optimizing process parameters such as attachment methods, gassing, and agitation can help reduce cell environmental stress, ultimately improving productivity.
Comparison Of Single-Use And Steel Fermentors For Malaria Vaccine Production

Support the advancement of malaria vaccine development by leveraging innovative bioprocessing solutions to enable efficient, scalable, and accessible vaccine production worldwide.
Intuitive Bioprocess Scale-Up From Bench Scale To Pilot Scale

This study explores scaling a high-demand fed-batch process from bench to pilot scale, highlighting control parameter differences at 50L and 500L while maintaining consistent growth and product titers.
Advances In Flow-Through Technology To Enhance mAb Polishing

Optimize your monoclonal antibody purification with cutting-edge flow-through chromatography. Learn how POROS resins enhance polishing efficiency, improve aggregate removal, and streamline bioprocessing.
The Importance Of Quality In Raw Material Selection

Learn how to select high-quality raw materials for cell-based manufacturing in this exploration of the criticality of raw materials, from preclinical development to commercialization.
Enhanced mAb Production With High-Intensity Perfusion CHO Medium

Reach new heights in mAb production with a high-intensity perfusion CHO medium designed to support consistently high product yield and quality in continuous perfusion cultures using CHO-K1 cells.
The Value Of Peptones For Enhancing Biopharmaceutical Productivity

Peptones, versatile media additives derived from various sources, offer numerous benefits for biopharmaceutical production.
Difco TC Yeastolate Ultra-Filtered (TCY UF) In Scale-Up Optimization

Explore how Difco™ TC Yeastolate ultra-filtered (TCY UF) enabled over 100% improvement in titer for CHO cell culture through feed optimization and bioreactor scalability in a real-world application.
Production And Clarification Of Lentiviral Vectors

Explore scalable processes for lentiviral vector production and clarification at the 50 L scale, utilizing the CTS LV-MAX system and single-use bioreactors for robust gene therapy manufacturing.
Ensure The Safety And Purity Of Your Cell Therapy Product With Mycoplasma And Sterility Testing

Discover how the Applied Biosystems™ MycoSEQ™ Plus system and Applied Biosystems™ SteriSEQ™ Rapid Sterility Testing System can help accelerate your cell therapy manufacturing process.
Achieving Titer Increase Up To 4-Fold While Maintaining Product Quality

Discover customizable solutions for antibody manufacturing, as well as services for media optimization, feeding strategy optimization, and format conversion.
Development To Large-Scale cGMP Production

For manufacturers working with a dry powder medium (DPM), early consultation with a supplier can increase the likelihood of success. Uncover a two-phase scale-up strategy for the production of DPM.
Rapid, Seamless Upstream Process Development And Scale-Up For CHO-K1 Cells

Accelerate your biotech company's scale-up process while delivering consistent and strong cell growth, productivity, and product quality.
Lentiviral Vector Characterization For Cell And Gene Therapy Manufacturing

This study focuses on characterizing recombinant LVVs used in gene-modified cell therapies, utilizing two real-time PCR assays adapted to the QuantStudio™ Absolute Q™ Digital PCR System.
High-Performance Extraction And Quantitation Of Host-Cell Residual DNA

This study presents a high-efficiency method for extracting and quantifying residual DNA from host cells using a semi-automated, high-throughput workflow.
Maximizing Scale-Up Efficiency Of A mAb Upstream Process

This study demonstrated the effectiveness of a medium and feed system when tested at three different scales for its ability to high-quality, fed-batch monoclonal antibodies.
Mycoplasma Testing In Monoclonal Antibody Production

Prevent costly disruptions in your bioproduction process. Discover how a PCR-based method can quickly detect the presence of mycoplasmas in raw materials, cell banks, and in-process and lot-release samples.
Simultaneous Extraction Of Mycoplasma, MMV, And Vesivirus Nucleic Acids From A Single Sample

Achieve early detection of cell culture contamination with a nucleic acid extraction system to provide an integrated system for rapid and sensitive detection of mycoplasma, MMV, and vesivirus.
Residual Plasmid Quantification In Gene Therapy Manufacturing Workflows

This article details the design and application of a Plasmid DNA - Kanamycin Resistance Gene (pDNA-KanR) kit for residual plasmid quantification in gene therapy manufacturing.
Optimize T Cell Phenotype With One-Step Isolation And Activation

This comparative bench-scale study features active-release beads that could improve the reliability, consistency, and longevity of cell therapy treatments.
Overcoming Rapid Growth Challenges With Process Liquid Preparation

With a helpful assessment and the right process liquid preparation services, the CDMO featured in this study was able to find a path toward meeting the surge in demand for a client's therapeutic .
Explore A High-Performing Basal Medium And Feed Pairing

A customer sought to replace a chemically defined CHO medium with a more efficient medium and feed pairing strategy in bioreactors.
Buffers And Process Liquids For Biopharmaceutical Production: Considerations For Scale-Up And Outsourcing

For small and midsize biopharmaceutical organizations, outsourcing buffer and process liquid preparation, quality testing, and storage could significantly streamline operations and reduce regulatory risk.
Advancing Cell Therapy Manufacturing: Rapid Sterility Testing

The rapid sterility test kit used in the study was able to quickly detect bacteria and fungi in complex cell therapy product matrices, detecting six species listed in USP chapter <71>.
Screening Peptones, Including "Titration And Blending" Protocol Examples

Dive into the importance of peptone selection, instructions for reconstituting peptone powders for mammalian cell culture, and discover starter packs containing commonly used peptones for specific applications.
Enabling CDMOs To Focus On Core Priorities

Explore innovative solutions for CDMO's striving to remain competitive as the biopharmaceutical market grows and evolves.
Enhanced T Cell Expansion While Maintaining Early Memory Cell Phenotype

Study the development and performance of this animal origin-free (AOF) T cell culture medium designed for T cell expansion through an experiment comparing it to other AOF or xeno-free basal offerings.
Uninterrupted Supply To Meet Demand

Explore a solution for biopharmaceutical companies concerned about the risks an increase in campaign volume can pose to their production timeline.
cGMP Assurance of Supply Services

Explore the stocking solution offered to a mid-sized CDMO in need of a high volume of safety stock inventory to support their customer portfolio growth.
Exploring The Future Of Viral Vector Development And Production

The demand for viral vectors continues to grow, making addressing the challenges related to their manufacturing and scale-up increasingly critical.
Achieve Manufacturing Scale For Your Viral Vector Production

Elevate your viral vector production to commercial scale by choosing the optimal production system paired with the right single-use bioreactor combination.
Production And Purification Of AAV At The 50 L Scale

Explore data demonstrating the performance of a scalable system for AAV manufacturing that enables gene therapy researchers to utilize a single system throughout the entire development process.
Compatible Platforms For Microbial Identification

Reduce the time-to-results for microbial identification by taking advantage of the shorter run cycle and off-instrument data analysis provided by this optimized and validated workflow.
Rapid Mycoplasma Detection For Bioproduction Sample Testing

Streamline your workflow while enabling early and accurate detection of mycoplasma contamination with mycoplasma detection and sample preparation kits
A One-Step Isolation And Activation Kit To Optimize T Cell Phenotypes

Produce your desired T cell phenotype while controlling the activation with user-defined dissociation of the active-release beads at any time after activation.
Transitioning From Using RUO To cGMP Chemicals For Clinical Trials

Learn about the common challenges and risks associated with accelerating your molecule's timeline from lab to clinic, along with important supply chain considerations for emerging biopharma companies.
Critical Considerations For Buffer Preparation

Learn about the steps of buffer development, supply approach and strategy selection, choosing between in-house and outsourcing buffer activities, and other related buffer use topics.
Powerfully Simple Digital PCR

Evaluate the performance of an E. coli kit based on it's detection sensitivity, quantification accuracy, and replicate uniformity as it performed when tested on a Digital PCR System.
Target T Cell Isolation And Magnetic Bead Removal At High Efficiency

Explore a cell processing platform using magnetic beads to support the cell therapy industry through struggles with challenges such as product quality and slow, inefficient manufacturing processes.
Streamline Cell Therapy Manufacturing With Rapid And Reliable Bead Removal

Explore a Magnetic Separation System designed to enable closed, fully automated, and rapid cell isolation and bead removal, while decreasing variability in cell therapy manufacturing.