Advances In Flow-Through Technology To Enhance mAb Polishing

Optimizing monoclonal antibody (mAb) purification is more critical than ever as new antibody formats introduce complex purification challenges. Advances in flow-through chromatography—especially hydrophobic interaction chromatography (HIC) and mixed-mode chromatography—offer enhanced removal of impurities while supporting improved product quality and process efficiency. This application note explores innovative developments in flow-through mAb polishing, showcasing how innovative chromatography resins, including the POROS HIC family, streamline downstream processing. Case studies demonstrate how these resins optimize aggregate removal, boost recovery rates, and improve scalability.

Discover how these advances can enhance your purification strategy. Download the full application note now.

_{For Research Use or Further Manufacturing. Not for diagnostic use or direct administration into humans or animals.}