FEATURED ARTICLES

• Evaluating Clone Performance And Cell-Specific Productivity

  See how continuous process monitoring and automated at-line analytics support confident CHO clone ranking, consistent cultivation, and scale-up by connecting pH, viable cell density, and more.

• Enhancing Laboratory Efficiency And Accelerating Time To Market

  Explore how automated screening can accelerate CLD while preserving selection confidence, identifying promising candidates that manual methods may miss, and predicting poor fed-batch performers.

• A Comparison To Traditional Clone Screening Platforms

  See how 46 CHO clones performed across automated, deep-well, and microbioreactor fed-batch cultures, using cell density, viability, and IgG concentration to evaluate clone performance.

• Cell Type Setting Considerations For Counting Clumpy Cells

  Cell clumping can dramatically affect counting accuracy. Learn how declustering, mixing, and aspiration settings influence cell density measurements and help generate more reliable viability.

• Using dSEC-7 Column For Separation And Length Determination Of mRNA

  mRNA analysis depends on methods that can separate broad size ranges. Learn how retention time can help estimate transcript length and complement capillary electrophoresis workflows.

• What Is Size Exclusion Chromatography (SEC)?

  Aggregation can compromise mAb quality at many stages of development. Learn why size exclusion chromatography is a trusted approach for detecting aggregates and supporting confident characterization.

• Peptide Mapping Of Adeno Associated Virus Capsid Proteins

  Peptide mapping helps reveal AAV capsid protein identity, sequence coverage, and potential modification patterns, giving gene therapy teams a clearer view of viral protein quality across workflows.

• Native RPLC For ADCs: How Column Hydrophobicity Shapes DAR Separation

  ADC characterization does not have to be overwhelmed by complex intact MS profiles. Smart column selection can improve separation, clarify critical quality attributes, and make ADC analysis easier.

• Sample Clean-Up After N-Linked Glycan Release And Labeling

  Glycan profiling starts with effective clean-up. See how comparable recovery across key labeled glycans and sialylated glycan groups can support confident analysis while helping labs manage costs.

• What Is Drug Antibody Ratio (DAR) And How It Relates To Biotherapeutics?

  DAR is a key quality attribute that shapes ADC potency, safety, stability, and developability. Learn why accurate measurement and control are essential as ADC pipelines expand and expectations rise.

• HPLC Method Development For Monoclonal Antibody Aggregates With SEC

  SEC for monoclonal antibodies is not always as simple as choosing a column and running PBS. Secondary interactions can affect recovery, making thoughtful method development essential.

• Protein Purification By HPLC: Methods, Benefits, And Best Practices

  Read about how HPLC protein purification enables precise, reproducible isolation of target proteins from complex mixtures while preserving structure and activity—supporting high-purity workflows.

• Exploring Protein Purification Methods: Essential Techniques

  Effective protein purification starts with matching the method to the molecule and the application. Learn how scale, throughput, purity goals, and empirical optimization influence successful recovery.

• Why Advanced Off-Target Analysis Is Critical For CRISPR's Success

  CRISPR is transforming medicine, but precision remains critical. Off-target effects pose ongoing safety challenges, driving the need for rigorous, multidimensional evaluation strategies.

• CRISPR Reagents Enable High Efficiencies Of Editing And HDR In iPSCs

  Achieving consistent Homology Directed Repair (HDR) in iPSCs requires optimized CRISPR design and workflows. See how advanced reagents and targeted enhancement strategies improve insertion efficiency.

• Advancing The Possibilities Of Protein Engineering Into The Future

  Protein engineering is rapidly shifting toward faster, design-driven innovation. Discover how AI, advanced synthesis, and scalable workflows unlock new applications in drug development.

• The Mutagenesis Handbook: Application Basics And Protocols

  Learn how to design and execute mutagenesis experiments with practical guidance on primer design, PCR strategies, and troubleshooting that helps improve results and reduce trial-and-error in the lab.

• The CRISPR Basics Handbook

  Gain a clear understanding of CRISPR fundamentals, from molecular mechanisms to experimental design, as well as how to improve precision and reduce off-target effects for more reliable results.

• Improved Methods For CRISPR-Cas9 Homology-Directed Repair

  Precise genome editing depends on improving HDR efficiency. Learn how guide selection, template design, homology arm optimization, and delivery strategies work together to drive higher-fidelity edits.

• Driving Antibody Discovery With Synthetic Biology

  Synthetic biology is transforming antibody discovery. See how enabling faster screening, greater diversity, and more precise optimization of candidates improves performance and development success.