3D Biology And Spatial Profiling: Expert Insights

Human-relevant models and spatial profiling are revolutionizing drug discovery by offering more predictive, human-like data than traditional animal models and 2D cultures. Technologies such as organoids and 3D cell cultures closely replicate human biology, which leads to more accurate disease modeling, drug screening, and advancements in precision medicine. Spatial profiling adds another layer of insight by mapping cellular interactions and biomarker distribution, which is crucial for developing personalized treatments for conditions like cancer, neurodegenerative diseases, and autoimmune disorders.

These innovative approaches not only reduce dependence on animal testing—aligning with evolving regulatory standards—but also improve early toxicity assessments. By bridging the gap between preclinical research and clinical trials, they accelerate the development of safer, more effective therapies.

Danaher’s Life Sciences companies are at the forefront of this transformation, offering integrated solutions that support human-relevant models and spatial profiling. Explore how Danaher can help you advance your drug discovery efforts.