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ABOUT CORNING LIFE SCIENCES
Corning Life Sciences is a global, leading manufacturer of lab tools for growing cells, bioprocess manufacturing, liquid handling, benchtop equipment, among other solutions for life sciences. Corning strives to improve efficiencies and develop innovations that enable researchers to harness the power of cells to create breakthrough discoveries in research areas like cancer, primary cells, stem cells, drug discovery, cell and gene therapy and lab automation. Learn more at www.corning.com/lifesciences.
FEATURED ARTICLES
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This study evaluates the performance of a flexible, automated fixed bed reactor (FBR) system during AAV production, comparing it with a similar FBR system and 2D cell culture controls.
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Directly inoculated your HEK293 cells into the bioreactor from cryopreservation vials or bags just using this fixed bed bioreactor (FBR) system's automated process steps.
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Coatings for cell culture surfaces are an important factor in maintaining the health and pluripotent properties of stem cells.
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Learn about four promising regenerative medicine strategies including their current state, and the potential translational impacts and challenges they present.
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Discover how Corning's Insect Cell serum-free medium outperforms other commercial media in yield, doubling time, and cell viability by diving into the study results.
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This study compares a serum-free medium to other commercially available pre-hydrated media to measure it's effectiveness in supporting the culture of adherent Vero cells.
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Explore a new optical device that performs real-time, user-friendly, and label-free measurements of lentiviral vector physical titer and size distribution.
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This study describes a “plug-and-play” setup for cell expansion in Corning CellCube 25-layer modules in the absence of a bioreactor controller.
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Review our work to establish a protocol for culturing Vero cells in serum-free medium on the Corning CellCube System, a compact and scalable method for mass culture of attachment-dependent cells.
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This study establishes basic cell culture parameters for expansion of DF-1 cells in the Corning CellCube System—a compact and scalable method for mass culture of attachment-dependent cells.
VIDEOS
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During each Cell & Gene Live, our audience can submit real-time questions for our expert panelists. Watch and listen as Michael Blackton and John Lee provide detailed, insightful responses to our audience questions on everything from how changing from a lab-based adherent protocol to suspension scalable protocol improved the cell product to whether a container with lesser cells, identical cell density, and composition be used for establishing stability for cell therapy products, and much more.
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During Cell & Gene Live, "Scaling Cell Therapies Part 2: Establishing Comparability in Manufacturing," Michael Blackton and John Lee provided detail on how successful comparability studies are designed and executed. They covered the in-process and release testing requirements, as well as the common and uncommon pit falls that have been encountered.
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For cell-based products, donor-to-donor variability is the primary source of complexity associated with establishing product comparability. In this segment of Cell & Gene Live, "Scaling Cell Therapies Part 2: Establishing Comparability in Manufacturing," Michael Blackton and John Lee cover why donor-to-donor variability is an on-going challenge and potential solutions.
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Here, during this segment of Cell & Gene Live, "Scaling Cell Therapies Part 2: Establishing Comparability in Manufacturing," Michael Blackton and John Lee highlight the various ways to demonstrate our understanding of how the process influences the product, as well as how the product’s structure influences its clinical function.
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As a therapy proceeds through Phases I / II and into Phase III clinical trials, the comparability burden increases. As the body of knowledge increases, the comparability burden evolves. Some tests may be removed while others are added, and assumptions may change with data. In this segment of Cell & Gene Live, "Scaling Cell Therapies Part 2: Establishing Comparability in Manufacturing," Michael Blackton and John Lee break down the comparability requirements from early- to late-stage programs.
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During this Cell & Gene Live, "Scaling Cell Therapies Part 2: Establishing Comparability in Manufacturing," Cell & Gene's Chief Editor, Erin Harris, Michael Blackton, former SVP Cell Therapy Manufacturing at Nurix Therapeutics, and John Lee, SVP, Head of Cell Therapy at Center for Breakthrough Medicines, talk through the CGT sector's greatest struggles with comparability. Indeed in this segment, Blackton and Lee cover the sector's biggest challenges to date from the need to truly understand the product to precise analytics and eliminating silos, and more.
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In this video our application scientists walk you through common research goals and the most suitable 3D cell culture solutions for each.
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There are many harvesting options depending on the cell line and application. In this video we discuss some tips and tricks for harvesting cells.
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The Corning® Matribot® bioprinter uses a revolutionary cooling syringe printhead technology that allows you to dispense 3D droplets or droplet arrays for organoid applications.
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With gas-permeable film, this closed system offers more surface area within a compact footprint. Watch this short video to learn more.
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We visit the MEARY Center to see how they produce new cells and new gene therapy drugs to treat patients suffering from autoimmune, hematological, and cardiac diseases, and so much more.
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In the complex world of cell and gene therapy, having a seasoned partner to guide you through uncharted production territory is critical to success.
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Corning’s Field Applications Specialists work with scientists like you to overcome complex manufacturing challenges and streamline the path to production.
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The Ascent FBR System’s novel mesh substrate intensifies cell growth surface area to produce high cell yields more efficiently.
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When you need a reliable path from research to bioprocessing try efficient tools like the Corning® HYPERFlask® cell culture vessel.
CONTACT INFORMATION
Corning Life Sciences
836 North Street
Tewksbury, MA 01876
UNITED STATES
Phone: 978-442-2288
Contact: Nicole Athanas
PRODUCTS
BROCHURES
- Rapidly Create Closed System Assemblies For A Customized Configuration
- Measure The Size And Concentration Of Nanoparticles In One Drop
- Corning® CellCube® System
- Frequently Asked Questions: Corning® CellCube® System
- Film Types For Corning® Single-Use Containers
- Automate To Accelerate: Meet The Corning® Matribot® Bioprinter
- Viral Vector Manufacturing And Cell Harvesting From A Single Bioreactor?
- Stack Facts: Scaling Up From Research To Clinical Applications
- Corning® Fetal Bovine Serum
- Corning® CellSTACK® Culture Chamber PEIpro® Transfection Protocol
- Guidelines For Use Of Erlenmeyer Flasks
- Corning® 5L Erlenmeyer Aseptic Transfer Cap For Transfer By Vacuum Or Positive Pressure
- Calculating Cellular Mass Balance After Corning® X-SERIES® Processing
- Corning® CellCube® Culture System Cell Expansion