Corning® CellCube® System

The Corning CellCube system provides a compact, perfusion-based method for the mass culture of attachment-dependent cells. CellCube modules consist of a series of 10, 25, or 100 parallel, polystyrene plates joined to create thin, sealed laminar flow spaces between adjacent plates. CellCube modules are available with either a Tissue Culture (TC)-treated growth surface or Corning CellBIND® surface for cell attachment. The surface treatment is applied to both sides of each layer to achieve available surface area ranging from 8,500 cm2 to 85,000 cm2 in a compact footprint. The system continually perfuses the cells with fresh medium for increased cell productivity. The CellCube system provides an environment that more closely simulates in vivo conditions than a static culture with its perfusion-based design. It mimics the constant fluid flow of in vivo conditions and reliably distributes nutrients and oxygen with low differential gradients across all attached cells throughout the modules.