Thermo Fisher Scientific Bioproduction Articles

  1. Development To Large-Scale cGMP Production 7/25/2024

    For manufacturers working with a dry powder medium (DPM), early consultation with a supplier can increase the likelihood of success. Uncover a two-phase scale-up strategy for the production of DPM.

  2. Rapid, Seamless Upstream Process Development And Scale-Up For CHO-K1 Cells 6/28/2024

    Accelerate your biotech company's scale-up process while delivering consistent and strong cell growth, productivity, and product quality.

  3. Lentiviral Vector Characterization For Cell And Gene Therapy Manufacturing 6/20/2024

    This study focuses on characterizing recombinant LVVs used in gene-modified cell therapies, utilizing two real-time PCR assays adapted to the QuantStudio™ Absolute Q™ Digital PCR System.

  4. High-Performance Extraction And Quantitation Of Host-Cell Residual DNA 6/19/2024

    This study presents a high-efficiency method for extracting and quantifying residual DNA from host cells using a semi-automated, high-throughput workflow.

  5. Maximizing Scale-Up Efficiency Of A mAb Upstream Process 6/17/2024

    This study demonstrated the effectiveness of a medium and feed system when tested at three different scales for its ability to high-quality, fed-batch monoclonal antibodies.

  6. Mycoplasma Testing In Monoclonal Antibody Production 6/17/2024

    Prevent costly disruptions in your bioproduction process. Discover how a PCR-based method can quickly detect the presence of mycoplasmas in raw materials, cell banks, and in-process and lot-release samples.

  7. Simultaneous Extraction Of Mycoplasma, MMV, And Vesivirus Nucleic Acids From A Single Sample 6/7/2024

    Achieve early detection of cell culture contamination with a nucleic acid extraction system to provide an integrated system for rapid and sensitive detection of mycoplasma, MMV, and vesivirus.

  8. Residual Plasmid Quantification In Gene Therapy Manufacturing Workflows 6/7/2024

    This article details the design and application of a Plasmid DNA - Kanamycin Resistance Gene (pDNA-KanR) kit for residual plasmid quantification in gene therapy manufacturing.

  9. Optimize T Cell Phenotype With One-Step Isolation And Activation 5/10/2024

    This comparative bench-scale study features active-release beads that could improve the reliability, consistency, and longevity of cell therapy treatments.

  10. Overcoming Rapid Growth Challenges With Process Liquid Preparation 5/10/2024

    With a helpful assessment and the right process liquid preparation services, the CDMO featured in this study was able to find a path toward meeting the surge in demand for a client's therapeutic .