Thermo Fisher Scientific Bioproduction Articles

  1. Maximizing Scale-Up Efficiency Of A mAb Upstream Process 6/17/2024

    This study demonstrated the effectiveness of a medium and feed system when tested at three different scales for its ability to high-quality, fed-batch monoclonal antibodies.

  2. Mycoplasma Testing In Monoclonal Antibody Production 6/17/2024

    Prevent costly disruptions in your bioproduction process. Discover how a PCR-based method can quickly detect the presence of mycoplasmas in raw materials, cell banks, and in-process and lot-release samples.

  3. Simultaneous Extraction Of Mycoplasma, MMV, And Vesivirus Nucleic Acids From A Single Sample 6/7/2024

    Achieve early detection of cell culture contamination with a nucleic acid extraction system to provide an integrated system for rapid and sensitive detection of mycoplasma, MMV, and vesivirus.

  4. Residual Plasmid Quantification In Gene Therapy Manufacturing Workflows 6/7/2024

    This article details the design and application of a Plasmid DNA - Kanamycin Resistance Gene (pDNA-KanR) kit for residual plasmid quantification in gene therapy manufacturing.

  5. Optimize T Cell Phenotype With One-Step Isolation And Activation 5/10/2024

    This comparative bench-scale study features active-release beads that could improve the reliability, consistency, and longevity of cell therapy treatments.

  6. Overcoming Rapid Growth Challenges With Process Liquid Preparation 5/10/2024

    With a helpful assessment and the right process liquid preparation services, the CDMO featured in this study was able to find a path toward meeting the surge in demand for a client's therapeutic .

  7. Explore A High-Performing Basal Medium And Feed Pairing 5/8/2024

    A customer sought to replace a chemically defined CHO medium with a more efficient medium and feed pairing strategy in bioreactors.

  8. Buffers And Process Liquids For Biopharmaceutical Production: Considerations For Scale-Up And Outsourcing 5/7/2024

    For small and midsize biopharmaceutical organizations, outsourcing buffer and process liquid preparation, quality testing, and storage could significantly streamline operations and reduce regulatory risk.

  9. Advancing Cell Therapy Manufacturing: Rapid Sterility Testing 5/7/2024

    The rapid sterility test kit used in the study was able to quickly detect bacteria and fungi in complex cell therapy product matrices, detecting six species listed in USP chapter <71>.

  10. Screening Peptones, Including "Titration And Blending" Protocol Examples 5/3/2024

    Dive into the importance of peptone selection, instructions for reconstituting peptone powders for mammalian cell culture, and discover starter packs containing commonly used peptones for specific applications.