Insights on Discovery

  1. What ASCO 2025 Means For The Future Of Oncology Trials 6/13/2025

    Review the ASCO 2025 Annual Meeting, highlighting oncology trials and the need for agile, globally capable CRO partners to navigate today’s evolving trial landscape.

  2. Factors Influencing CD34+ Cell Collection Efficiency In Leukapheresis 6/3/2025

    Efficiently collecting sufficient peripheral blood stem cells is paramount for successful transplantation, necessitating a deeper understanding of influencing factors and procedural nuances.

  3. Broad Biodistribution And Expression Of Allele-Selective LETI-101 5/28/2025

    Discover how LETI-101, a novel precision-based CRISPR treatment, can leverage targeted delivery and broad brain distribution to transform Huntington's disease treatment.

  4. CRISPR Portfolio, Modalities Accelerate Candidate Identification 5/28/2025

    See how this cutting-edge, AI-driven genome editing technology can accelerate the development of precise, clinically viable therapies for genetic diseases.

  5. Peripheral Blood Mononuclear Cell (PBMC) Isolation Using Cell Fractionation Filters 5/28/2025

    Discover how this Peripheral Blood Mononuclear Cell (PBMC) isolation method can transform CAR-T manufacturing by reducing costs, accelerating timelines, and improving patient accessibility.

  6. Signature Of Base Editor RNA Edits And Reduced Exogenous RNA Editing 5/28/2025

    Learn how this groundbreaking method for distinguishing base editor-induced RNA edits can enhance the safety and efficacy of genomic medicines.

  7. Electroporation, LNPs For Targeted CRISPR/Cas9 Gene Editing In T-Cells 5/28/2025

    This study compared non-viral transfection methods in primary human T-cells, demonstrating the feasibility of an LNP-based process encapsulating CRISPR/Cas9 and HDR template DNA in a single payload.

  8. CRISPR-Associated RNA-Guided Nucleases For Precise Gene Editing 5/28/2025

    Explore how advanced CRISPR technologies and proprietary delivery systems are transforming genomic medicine by enabling precise gene editing for a wide range of therapeutic applications.

  9. CRISPR System Enables CNS Biodistribution, mHTT Protein Reduction 5/28/2025

    Discover how a diverse collection of RNA-guided nucleases, base editors, and reverse transcriptase editors with unique PAM recognition sequences can enable flexible and precise genome editing.

  10. AAV Vector Used To Deliver Gene Editing Tools To The Brain 5/28/2025

    Discover how LETI-101's promising preclinical results and advanced manufacturing strategies are advancing gene editing therapy for Huntington's Disease.