Insights on Discovery
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Creating An Effective Pre-Clinical Model Of Bone Marrow
4/9/2024
A Bone Marrow-Chip (BM-Chip) was created to recapitulate relevant hematopoietic cell types in a three-dimensional (3D), mechanically active next-generation in vitro model.
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Revolutionizing Viral Infectious Disease Research And Drug Discovery
4/8/2024
Learn how Organ-Chips are being used to rapidly identify promising treatments, investigate virus evolution, and analyze how mechanical forces influence the innate immune response to viral infections.
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Converting iPSC To T Cells: Key Challenges And Considerations
3/27/2024
Explore how by addressing challenges in differentiation, clone selection, and manufacturing, iPSC-based T cell therapies could revolutionize cancer treatment and other diseases.
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Targeting Macular Degeneration With Stem Cell Therapy
3/27/2024
A novel stem-cell therapy based upon iPSC-derived RPE cell transplantation was conceptualized as a promising new treatment for AMD and other retinal diseases.
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How Close Are We To The Clinic?
3/27/2024
Organoids are offering new possibilities in therapeutic screening, regenerative medicine, and even organ transplantations. However, there are still several challenges to overcome.
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Three Key Considerations For Optimizing Process Development
3/21/2024
When it comes to process development, timing, technology, and partners all merit careful consideration. Explore expert insights into these three crucial factors.
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The Role Of Early Characterization Studies In The Assessment Of Advanced Therapeutic Potency
3/21/2024
Early product characterization can serve to uncover crucial information about an advanced therapeutic candidate, affording new insight into its CQAs and helping to shape better analytical assays.
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Novel Repression System For Gene Expression Regulation During Recombinant Adeno-Associated Virus And Lentiviral Vector Manufacturing
3/21/2024
Review a presentation demonstrating the CuO-CymR system’s ability to effectively inhibit GOI expression during plasmid transfection as well as how it can facilitate toxic gene packaging during LV and rAAV manufacturing.
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Building Biopharma Resilience In Developing Gene Therapies
3/18/2024
Learn about the opportunities and challenges surrounding gene therapies, the importance of collaboration between biopharma startups and academia, difficulties with the talent pipeline, and more.
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Quality Versus Quantity In T-Cell Production
3/15/2024
Technological advances have made it possible to produce high-quality T cells at scale, providing a boon for T-cell manufacturing.