Insights on Discovery

1. The Continuing Challenge Of Drug-Induced Liver Injury 9/24/2026

   Recent liver safety concerns highlight the limits of conventional preclinical testing. Human-relevant models could help researchers detect drug-induced liver injury earlier and reduce costly setbacks.

2. CRISPR Nucleases And Proprietary Reverse Transcriptases For Precise Gene Editing 9/24/2026

   Mining a database of over 10 billion natural proteins has yielded proprietary reverse transcriptases and engineered RT editing systems capable of achieving precise gene editing in vivo.

3. Metabolic Shift Monitoring Of Immune Cells During Differentiation 9/22/2026

   Real-time tracking of glucose and lactate kinetics reveals critical metabolic shifts during immune cell differentiation, enabling quantitative evaluation of cellular state changes.

4. Visualizing The Metabolic Profile Of Immune Cells With Metabolic Inhibitors 9/22/2026

   Continuous in-line measurement tracks real-time shifts in cellular energy pathways under metabolic inhibition, delivering precise insights into immune cell function and dynamics.

5. Improving Speed, Reproducibility And Flexibility In Cellular Imaging 9/17/2026

   See how automated microscopy combines imaging, robotics, and software to reduce manual intervention and support complex cellular imaging workflows configured around specific applications.

6. Enabling Process Monitoring, Product Characterization, And Quality Control 9/16/2026

   Optical microscopy reveals biological structures, behaviors, and interactions throughout development. Learn how advanced imaging and analysis support cellular research and more.

7. Why The Traditional Approach To Evaluating Gene Editing Is Not Your Only Option 9/7/2026

   De-risk genetic medicine development with a phased evaluation approach. Gain rapid, data-driven feasibility insights before major investments, enabling smarter decisions and faster clinical progress.

8. Robust Database Characterizes And Optimizes Product Development 8/29/2026

   Integrating material characterization data with process parameters accelerates drug development, reduces empirical testing, and strengthens regulatory compliance.

9. CRISPR-Cas9 KO Cell Line Generation And Development 8/24/2026

   See how CRISPR-generated FKRP knockout muscle cells and a high-throughput On-Cell Western method can quantify α-dystroglycan glycosylation restoration and support rAAV-FKRP potency testing.

10. Receptor Occupancy In The Era Of Multispecific Therapeutics 8/21/2026

    Receptor occupancy studies face new challenges as multispecific therapeutics introduce complex target engagement, receptor trafficking, cellular interactions, and assay interpretation considerations.