Insights on Discovery

  1. Preserving Genomic Data's Living Legacy 12/10/2025

    Public genomic datasets like TCGA transformed cancer research, guiding assay validation and cohort design. Today, matched biospecimens complete the loop between digital insight and biological confirmation.

  2. How To Design And Evaluate Bispecific Antibodies (BsAbs)? 11/25/2025

    Bispecific antibodies combine two antigen-binding sites to enhance efficacy and safety. Their design requires structural strategy, MOA-based evaluation, and rigorous screening for optimal therapeutic performance.

  3. Analytical Approach For Bispecific Antibody Quality Study 11/25/2025

    Bispecific antibody quality control demands advanced analytics to detect mispaired species, assess structural integrity, and confirm potency, ensuring safety and efficacy across diverse therapeutic applications.

  4. Empowering Antibody Discovery With ProSpeed™ 11/25/2025

    Integrating linear expression technology into single B cell workflows accelerates antibody discovery, enabling early functional screening, improved sensitivity, and cost-effective identification of diverse therapeutic candidates.

  5. Challenges And Solution In The Poly (A) Control For Plasmid And mRNA 11/25/2025

    Poly(A) tail integrity is critical for mRNA stability and translation. Advanced strategies optimize plasmid design, transcription, and purification to ensure consistent poly(A) control for therapeutic success.

  6. Early Discovery Of Functional Antibody Leads 11/25/2025

    Early functional screening accelerates therapeutic antibody discovery, improving hit rates and efficiency through advanced platforms like hybridoma upgrades, single B cell workflows, and tailored phage display strategies.

  7. Development Of Alternative BCDP Reagents For The Synthesis Of 5' -Terminal Phosphate Oligonucleotides 11/25/2025

    New alternative phosphitylating reagents reduce the safety hazards associated with BCDP, enabling a safer and effective synthesis of key oligonucleotide sequences.

  8. The Art Of Phosphitylation 11/24/2025

    Phosphorylation is key for bioactives, with phosphoramidites favored for high selectivity. Discover how choosing specific protecting groups and new technologies fine-tunes the synthesis process.

  9. Surveying Amino Acid Variability Among CHO Media 11/20/2025

    Variability in amino acid levels across CHO media can affect growth and product quality. Learn why real-time monitoring and proactive control strategies are key to improving process consistency.

  10. Reflect On 20 Years Of Cancer Research With MIRROR Biospecimens 11/17/2025

    Explore how the Matched & Integrated Repository for Rediscovered Oncology Research (MIRROR) for biospecimens can help unlock new discoveries from the tumors that shaped modern precision oncology.