Insights on Discovery
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Understanding RNA Higher-Order Structure Dynamics For CRISPR Applications
5/5/2025
Scientists are gaining valuable knowledge about the structural dynamics of guide RNAs used in CRISPR-Cas9. This deeper understanding could pave the way for improved gene editing tools.
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8 Best Practices For Immunogenicity Assay And Companion Diagnostic Development In AAV Gene Therapy
5/2/2025
Read more to understand why the partnership between gene therapy companies and diagnostic developers is crucial for advancing the field of gene therapy.
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How Translational Central Lab Services Facilitate Creative Solutions For Biomarker-Driven Studies
5/2/2025
Explore the rise of biomarker-driven clinical trials, their benefits, and the complexities involved in their execution to learn about the importance of planning and overcoming challenges in translational studies.
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High-Sensitivity Residual E. coli DNA Testing Supporting Biologics, CGT Development
4/23/2025
Advancements in high-sensitivity residual DNA testing enhance the precision of plasmid DNA purity analysis, ensuring compliance with regulatory standards critical for manufacturing processes.
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Selection And Evaluation Of Hybridization Capture Probes For LC/MS Analysis Of Oligonucleotides
4/23/2025
To overcome challenges in oligonucleotide LC/MS bioanalysis, consider optimizing probe design by evaluating alternative chemistries like PNA for improved recovery and chromatographic performance.
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Advancing Cytokine, Immune Cell Characterization For Precision Bioanalysis
4/23/2025
Unlock deeper insights into immune regulation and accelerate therapeutic discovery by adopting our next-generation inflammatory response assay.
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Expression Analysis Of CTLA-4, PD-1, And PD-L1
4/23/2025
Advance personalized immunotherapy in NSCLC by leveraging qPCR-based analysis of CTLA-4, PD-1, and PD-L1 expression to identify predictive biomarkers and guide more effective treatment strategies.
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Optimizing qPCR For Broad-Range Transcript Detection In Anti-PD-1 Therapy
4/23/2025
Optimize qPCR protocols for greater sensitivity and reproducibility to accurately measure immune-related gene expression and better identify patients who will benefit from anti-PD-1 immunotherapy.
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Quantifying, Mapping ATP Distribution Within Tissues To Inform Therapeutic Strategies
4/23/2025
Leverage quantitative mass spectrometry imaging of ATP distribution to enhance tumor model selection and optimize targeted therapy development through precise mapping of metabolic activity.
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Exploring The Spatial Distribution Of mRNA-Lipid Nanoparticles Using MALDI MSI
4/23/2025
Learn how leveraging high-resolution MALDI-MSI can advance the development of lipid nanoparticle-based therapies, uncovering spatial biodistribution, pharmacokinetics, and organ-specific variability.