Insights on Discovery

  1. Materials Matter: Reframing Raw Material Strategy In Cell And Gene Therapy Development 5/1/2026

    Scaling iPSC-based therapies from lab to CGMP manufacturing demands tightly controlled cryopreservation, risk-based QC, and strategic automation to preserve cell viability, consistency, and regulatory readiness.

  2. Sensitive Viral Safety Testing For Adventitious Virus Detection 4/20/2026

    Discover a modern approach to adventitious virus detection that shows how targeted sequencing can achieve sensitive, comprehensive viral safety testing aligned with ICH MAP, RAP, and HAP expectations.

  3. Direct Cell Lysis Enables Rapid And Robust VCN Quantification 4/20/2026

    Explore a faster approach to vector copy number measurement that replaces DNA extraction with direct cell lysis and digital PCR, delivering accurate, reproducible results across fresh and frozen samples.

  4. Enhanced Lentiviral Vector Characterization Using Digital PCR 4/20/2026

    Digital PCR offers a precise, scalable approach to lentiviral vector characterization, enabling reliable genome titer, vector copy number, and RCL detection while reducing variability.

  5. Analytical Performance Evaluation Of A Bead-Based Cytokine Assay 4/17/2026

    Reliable IFN‑γ measurement is critical for understanding T cell function. See how analytical rigor, from accuracy to matrix effects, supports consistent cytokine quantification across development.

  6. ADC Development Grows More Complex — SPR Insights Bring Clarity 4/14/2026

    Explore how real-time kinetic analysis reveals how conjugation, linker chemistry, and drug loading influence antibody–antigen interactions, while enabling sensitive detection of anti-drug antibodies.

  7. What FDA CRLs Reveal About CCIT 4/14/2026

    FDA rejection letters show common CCIT gaps — low sensitivity and incomplete validation. Spotting these trends helps teams strengthen integrity testing and avoid approval delays.

  8. Evaluating Carryover When Using A TOC Analyzer 4/10/2026

    Accurate TOC results shouldn’t depend on sample order. See how low-level measurements remain reliable even after high-TOC analysis, helping reduce false positives and streamline decisions.

  9. In-Line Monitoring Of Culture Medium Using Live Cell Metabolic Analyzer 4/7/2026

    Continuous in-line monitoring of glucose and lactate levels provides highly accurate, real-time data on cellular metabolism without the risks or data gaps associated with manual periodic sampling.

  10. Novel Cardiotoxicity Evaluation Method Using iPS-Derived Cardiomyocytes 4/7/2026

    Discover how real-time monitoring of glucose and lactate in iPS-derived cardiomyocytes reveals subtle drug-induced metabolic shifts that traditional screening methods often fail to detect.