Translational Research

  1. A Derivatization-Free LCMS Assay For 4β-hydroxycholesterol 1/23/2025

    Learn about a novel LCMS assay for 4β-hydroxycholesterol, a key biomarker for CYP3A activity. This derivatization-free method offers a faster and more efficient approach for clinical studies.

  2. Base Editing's Advantages When Combined With Non-Viral Delivery Methods 11/9/2024

    In this segment, Paul Kopesky of Beam Therapeutics shares information on the advantages base editing has over other gene editing approaches when combined with non-viral delivery methods as well as how Beam addresses the challenge of achieving therapeutic levels of editing and target tissues using non-viral delivery systems.

  3. Is The Sensitivity Of Optical Biosensors Important? 2/17/2022

    Explore why the sensitivity of optical biosensors is important for not just small molecules or fragment-based interactions but also for larger molecular entities.

  4. Why Material Definitions Matter In Cell And Gene Therapy 4/1/2026

    In this first segment of Cell & Gene Live, Anthony Blaszczyk, Ph.D., Senior Scientist at the U.S. Pharmacopeia, and Basak Clements, Ph.D., Founder and Senior Advisor at biomatria, were joined by Cell & Gene Chief Editor Erin Harris to discuss why cell and gene therapy, clearly defining raw, starting, and ancillary materials, and using those terms consistently, is critical.

  5. NK Cells' Role In Non-Viral Approaches To Genetic Engineering 11/9/2024

    Here, Dr. Robert Hariri, Chairman, founder, and CEO of Celularity, and Paul Kopesky, Ph.D., VP of Cell Therapy Process Development at Beam Therapeutics each share their take on the primary challenge to modifying NK cells.

  6. Elucidating The Role Of IL-18 In NSCLC Integrated Analysis 1/23/2025

    Hear how imaging mass cytometry, CyTOF, and single-cell sequencing unlock the secrets of the tumor microenvironment. Discover new insights into IL-18 and its impact on non-small cell lung cancer.

  7. Why iPSC Is Research Thriving 5/23/2025

    In this first segment of Cell & Gene Live, Unlocking the Potential of iPSC Therapies in Regenerative Medicine, Julie Allickson, Ph.D., Chief Technology Officer at Mayo Clinic's Center for Regenerative Biotherapeutics and Erin Kimbrel, Ph.D., Head of Cell & Gene Therapy Research at Astellas highlight the transformative potential of regenerative medicine and iPSC-based therapies. They emphasize the versatility and scalability of pluripotent stem cells, particularly for allogeneic applications that could eliminate the need for immunosuppression. These advances hold promise for treating complex diseases like diabetes, multiple sclerosis, and cardiac conditions, with the goal of making therapies more accessible and impactful on a global scale.

  8. Addressing Some Of The Most Common Surface Plasmon Resonance Questions 2/18/2022

    This video series addresses some of the most common SPR questions around evaporation, kinetics, sensitivity, and more.

  9. Achieving Stability For mRNA 1/29/2024

    Expert panelists for this Cell & Gene live event share some of things researchers are exploring to keep mRNA more stable.

  10. Is Evaporation Important For Optical Biosensors? 2/17/2022

    If your sample is open to evaporation effects causing your concentration to change, will your data, and potentially your conclusions, be unreliable?