Translational Research
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LC/MS Method For Measurement In Human Plasma
2/17/2025
According to the researchers, this plasma-based measurement has the potential to serve as a critical pharmacodynamic biomarker, facilitating the assessment of novel therapeutic approaches.
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Antisense Oligonucleotide Extraction Optimization Reveals Differences
2/17/2025
Our findings provide critical insights into refining ASO extraction protocols, which can enhance the accuracy of downstream analyses and support further research into ASO-based therapeutics.
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How To Best Optimize mRNA Production Workflows
4/11/2023
Multiple steps in the mRNA manufacturing process can appear more complex than they have to be. Learn how to simplify your approach and produce the best possible mRNA vaccines and therapeutics.
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Ori Spotlight: Building Early-Phase CGT Infrastructure For Translational Success
8/27/2025
Tighter integration between research, process development, and manufacturing is key to accelerating the translation of cell therapies from the lab to the clinic. Learn how a leading academic center is doing it.
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Electroporation As A Method For Genetic Modification
11/9/2024
In this clip, Dr. Robert Hariri, Chairman, founder, and CEO of Celularity, and Paul Kopesky, Ph.D., VP of Cell Therapy Process Development at Beam Therapeutics explain why electroporation has a higher gene editing efficiency than that of the viral vector method.
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Mitigate Clinical Risk In Cell Therapy Development With A GMP Compliant Process
4/21/2025
Help shape the future of medicine by building better, safer cell therapies. See how expertise in scalable, GMP-compliant cell engineering can effectively mitigate clinical development risks.
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LC/MS/MS Analysis Of Coproporphyrin 1, Coproporphyrin 3 In Human Plasma
2/17/2025
This innovative approach holds promise for reducing the need for extensive clinical drug-drug interaction studies, potentially streamlining the drug development process.
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Saudi Arabia Government Leaders Discuss Agile Manufacturing Beyond Borders
10/23/2022
Learn how government leaders in Saudi Arabia planned for biopharma resilience beyond borders and used agile manufacturing to prepare for the unknown.
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Non-Viral Tools For Genome Engineering
11/9/2024
In this segment, Dr. Robert Hariri, Chairman, founder, and CEO of Celularity, and Paul Kopesky, Ph.D., VP of Cell Therapy Process Development at Beam Therapeutics each share their own take on the tools, platforms, and non-viral approaches they have used for genome engineering of cell therapeutics.
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Analytics & Assays: Defining mRNA Therapeutic Impurities Early & Often
12/5/2023
mRNA therapeutics present a whole new safety paradigm not seen in vaccine applications. In this segment, Combined Therapeutics CSO Thomas Van Cott, Ph.D. and Omega Therapeutics Executive Director, Process Development and Analytical Sciences Jeff Atkinson, Ph.D. address the nuances of mRNA therapeutic analytics and assays.