Plasmid Complexity And The Push For Stronger CGT Material Control

In this segment of Cell & Gene Live, Anthony Blaszczyk, Ph.D., Senior Scientist at the U.S. Pharmacopeia, and Basak Clements, Ph.D., Founder and Senior Advisor at biomatria, were joined by Cell & Gene Chief Editor Erin Harris to discuss why complex materials such as plasmid DNA are critical yet challenging in cell and gene therapy because small variations (e.g., sequence or structure) can significantly impact the final product, and current analytical tools often struggle to fully characterize them.