product datasheets, catalogs, app notes

  1. Optimization, Validation And Implementation Of Retroviral Retentive Filters For Production of Adeno-Associated Virus (AAV) 8/19/2020

    Viral contamination is a risk for all biotechnology products. Establishing robust viral removal/inactivation steps mitigates the risk of adventitious and endogenous viral contamination and is essential for ensuring the safety of gene therapy products. Recent studies have shown that viral retentive filtration is one of the most robust steps in removing all types of viruses. In this study, we focused on the initial development process of the retroviral-retentive Viresolve® NFR filter.

  2. Considerations For Development Of A Platform Lentivirus Harvest Clarification Process For Cell And Gene Therapy 4/27/2020

    One of the new technologies emerging in the biotech manufacturing market is the use of viral vectors for cell and gene therapy. One commonly used viral vector in this space is lentivirus, due to its robustness to package and deliver target DNA. This work explores a variety of lentivirus harvest clarification options and items for consideration during manufacturing platform development of viral therapy production using suspension cell lines.

  3. High Yield And Functionality In The 3 L Mobius Stirred Tank Bioreactor 3/17/2020

    Stemline® XF MSC Medium promotes expansion of human mesenchymal stromal/stem cells (hMSCs) to high densities while maintaining cell identity and quality.

  4. Benzonase® endonuclease Safety Plus Emprove® Expert Data Sheet 1/15/2020

    Benzonase® endonuclease — the smart solution for DNA removal in biopharmaceutical production.

  5. Robust, Load Independent Viral Clearance In MAb Purification 11/15/2019

    How the Natrix Q chromatography membrane overcomes diffusion and binding capacity limitations and improved cost efficiency in a study measuring the removal of 4 model viruses.

  6. Mobius® Power MIX 1000 And 2000 Single-Use Mixers 1/4/2018

    The Mobius® Power MIX 1000 and 2000 combine high performance mixing technology with design features that make them easy to use. The impeller design and motor are based on our magnetically coupled NovAseptic® mixing technology, a proven mixing technology in stainless steel tanks. The system efficiently mixes the most challenging buffers, media and biopharmaceutical ingredients.

  7. Single-Use Modular Bioreactor For Fed-Batch And Perfusion Processes

    Efficiently implementing process intensification requires a combination of several different technologies, namely bioreactors capable of supporting high cell densities. Explore a single-use modular bioreactor for fed-batch and perfusion processes.

  8. A Versatile And Modality-Agnostic Aseptic Autosampling Solution

    Discover a versatile and modality-agnostic aseptic autosampling solution designed for reliable on-line sample analysis in near real-time without the need for manual intervention.

  9. Custom Research-Grade mRNA Manufacturing Services

    Explore two research-grade packages designed to support your mRNA needs at every stage of development.

  10. VirusExpress 293 AAV Production Platform

    The VirusExpress® Platform offers a transfection-based solution to Adeno-Associated Viral (AAV) production challenges, featuring a suspension adapted cell line, chemically defined medium, and a clinically relevant process dramatically reducing time to commercial production.