Insights on Discovery

  1. The Value Of Human Panel Testing Downstream Of Donor Screening In The Allogeneic Therapy Pipeline 3/31/2025

    Allogeneic cell-based therapies require rigorous donor screening for adventitious viruses. qPCR-based assays enhance detection accuracy, sensitivity, and specificity, supplementing serological testing to ensure safer drug development and production.

  2. Background-Free Analysis Of Mouse TILs 3/28/2025

    Syngeneic mouse tumor models are crucial for immunotherapy research, but variability in TILs and nonspecific binding complicate analysis. Discover how blocking reagents help but make the process more labor-intensive.

  3. Multicolor Immunophenotyping Of Human Tumor Cells 3/28/2025

    Flow cytometric phenotyping is crucial for immunotherapy to enable precise immune monitoring. Discover how standardized assays with an 8-color cocktail enhance the understanding of tumor immunity and therapeutic impacts.

  4. What Are ATMPs And Why Do They Matter? 3/28/2025

    Delves into the evolution of Advanced Therapy Medicinal Products (ATMPs), exploring their complex development, revolutionary potential in treating diseases, and the intricacies of cell and gene therapies.

  5. Real-Time PCR And Gene Expression Specificity 3/27/2025

    Gene expression analysis requires high specificity to ensure accurate results. Methods like probe-based assays offer greater specificity than dye-based detection.

  6. Efficient Gene Expression Profiling For Biomarker Identification 3/27/2025

    Solutions for automating qPCR and digital PCR (dPCR) gene expression analysis workflows can help translational research laboratories derive valuable gene expression profiles.

  7. Replicate Bioscience And Cytiva Collaborate To Deliver srRNA-LNP Vaccines 3/24/2025

    Discover how self-replicating RNA (srRNA) can revolutionize vaccine development with sustained protein expression, lower doses, and fewer side effects to advance next-gen RNA therapeutics.

  8. Fast And Scalable Fc Quantitation In Supernatants 3/24/2025

    In biopharmaceutical development, the Fc PAIA Titer assay offers a fast, cost-effective, and automatable solution for high-throughput Fc quantification to enhance efficiency, support research, and accelerate production advancements.

  9. Evaluating Compound Toxicity Effects On Healthy Intestinal Organoids 3/24/2025

    3D organoids enhance drug toxicity prediction and are crucial for anti-cancer drug development. Examine a method using 3D mouse intestinal organoids that aims to provide vital data on intestinal toxicity.

  10. Cell Culture Automation Of The 3D Cancer Spheroid Assay 3/24/2025

    Discover how automated 3D cell culture methods enhance efficiency and consistency in high-throughput drug screening to accelerate the discovery of new anti-cancer therapies.