Insights on Discovery
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Analysis Of LNP Lipids With Evaporative Light Scattering Detection
12/6/2024
Jump into this thorough analysis of lipids in LNP formulations using HPLC, a technique crucial for quality control in the production of mRNA vaccines and therapeutics.
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Development Of LNP Formulations Using The KNAUER NanoScaler
12/6/2024
Lipid nanoparticles (LNPs) offer a robust solution for nucleic acids. The NanoScaler system optimizes this technology, enabling scalable and reproducible LNP formulations for diverse applications.
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Quality Control Of Oligonucleotides Using HPLC Coupled To UV And MS Detection
12/6/2024
Efficient quality control of therapeutic oligonucleotides is crucial. Explore advanced methods combining HPLC-UV and mass spectrometry for precise impurity quantification and mass confirmation.
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High-Throughput Lipid Separation For LNP Formulations
12/6/2024
Lipid nanoparticles (LNPs) carry immense potential as delivery systems. Learn about the development of isocratic and gradient methods for high-throughput separation of lipids used in LNP formulations.
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Development And Optimization Of LNP Formulations
12/6/2024
The production of lipid nanoparticles (LNPs) is a process that demands robustness, scalability, and reproducibility. Examine the impact of key operational parameters on the efficacy of LNPs.
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EU Pharmaceutical Legislation Revisions
12/3/2024
The EU pharmaceutical legislation aims to balance public health priorities with industry growth, shaping a more sustainable and innovative pharmaceutical landscape in Europe.
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Daring To Learn From Failure: The Future Of Stem Cell Therapy
12/2/2024
Stem cell therapy has already revolutionized the field of oncology. But where do we go from here? Dr. Robert S. Negrin addresses three key areas of CAR T-cell therapy on the brink of innovation.
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Monolithic Columns As Downstream Processing Solutions For Lentiviral Purification
11/27/2024
Third-generation lentiviral vectors enable efficient gene delivery, but purification challenges limit in vivo applications. Monolithic columns and advanced assays show promise for downstream processes.
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Expanding Translational Research Concepts With Genedata Profiler
11/26/2024
The biopharma industry leverages Genedata Profiler to integrate, curate, and analyze diverse R&D data, enabling collaborative, compliant, and AI-driven translational research to optimize drug development.
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AI-Assisted Spatial Proteomics Of Immune Cells In Alzheimer's Brain
11/26/2024
AI-driven multiplexed imaging reveals neuroimmune interactions in Alzheimer’s disease, identifying immune cell subtypes near pathological hallmarks like β-amyloid plaques offering therapeutic insights.