Translational Research

1. A Derivatization-Free LCMS Assay For 4β-hydroxycholesterol 1/23/2025

   Learn about a novel LCMS assay for 4β-hydroxycholesterol, a key biomarker for CYP3A activity. This derivatization-free method offers a faster and more efficient approach for clinical studies.

2. How To Best Optimize mRNA Production Workflows 4/11/2023

   Multiple steps in the mRNA manufacturing process can appear more complex than they have to be. Learn how to simplify your approach and produce the best possible mRNA vaccines and therapeutics.

3. Ori Spotlight: Building Early-Phase CGT Infrastructure For Translational Success 8/27/2025

   Tighter integration between research, process development, and manufacturing is key to accelerating the translation of cell therapies from the lab to the clinic. Learn how a leading academic center is doing it.

4. Is Evaporation Important For Optical Biosensors? 2/17/2022

   If your sample is open to evaporation effects causing your concentration to change, will your data, and potentially your conclusions, be unreliable?

5. Analytics & Assays: Defining mRNA Therapeutic Impurities Early & Often 12/5/2023

   mRNA therapeutics present a whole new safety paradigm not seen in vaccine applications. In this segment, Combined Therapeutics CSO Thomas Van Cott, Ph.D. and Omega Therapeutics Executive Director, Process Development and Analytical Sciences Jeff Atkinson, Ph.D. address the nuances of mRNA therapeutic analytics and assays.

6. GLP And The Impact To Start Up Companies 4/18/2022

   Good Laboratory Practice is often used in laboratories and is necessary for specific investigations. What does it mean? And how can it help start-up companies? Watch this video to learn more.

7. Is The Sensitivity Of Optical Biosensors Important? 2/17/2022

   Explore why the sensitivity of optical biosensors is important for not just small molecules or fragment-based interactions but also for larger molecular entities.

8. LC/MS Method For Measurement In Human Plasma 2/17/2025

   According to the researchers, this plasma-based measurement has the potential to serve as a critical pharmacodynamic biomarker, facilitating the assessment of novel therapeutic approaches.

9. Validation Of An LCMS Hybrid Assay With EVOSEP Cleanup 2/17/2025

   By leveraging this innovative combination, the assay achieves detection limits comparable to traditional methodologies while enhancing overall efficiency and reliability.

10. Addressing Some Of The Most Common Surface Plasmon Resonance Questions 2/18/2022

    This video series addresses some of the most common SPR questions around evaporation, kinetics, sensitivity, and more.