Translational Research

1. Real-Time Monitoring And Automated Sampling For Enhanced Efficiency 3/17/2025

   Integrating real-time, in-line monitoring with automated sampling in bioprocessing enhances efficiency and precision. Discover how advanced spectroscopy provides non-destructive insights to optimize cell growth and productivity.

2. Why Material Definitions Matter In Cell And Gene Therapy 4/1/2026

   In this first segment of Cell & Gene Live, Anthony Blaszczyk, Ph.D., Senior Scientist at the U.S. Pharmacopeia, and Basak Clements, Ph.D., Founder and Senior Advisor at biomatria, were joined by Cell & Gene Chief Editor Erin Harris to discuss why cell and gene therapy, clearly defining raw, starting, and ancillary materials, and using those terms consistently, is critical.

3. Base Editing's Advantages When Combined With Non-Viral Delivery Methods 11/9/2024

   In this segment, Paul Kopesky of Beam Therapeutics shares information on the advantages base editing has over other gene editing approaches when combined with non-viral delivery methods as well as how Beam addresses the challenge of achieving therapeutic levels of editing and target tissues using non-viral delivery systems.

4. NK Cells' Role In Non-Viral Approaches To Genetic Engineering 11/9/2024

   Here, Dr. Robert Hariri, Chairman, founder, and CEO of Celularity, and Paul Kopesky, Ph.D., VP of Cell Therapy Process Development at Beam Therapeutics each share their take on the primary challenge to modifying NK cells.

5. Can You Run Crude Samples Using An SPR Instrument? 2/17/2022

   We explore a common misconception and provide examples of complex material being used in an SPR system.

6. Mitigate Clinical Risk In Cell Therapy Development With A GMP Compliant Process 4/21/2025

   Help shape the future of medicine by building better, safer cell therapies. See how expertise in scalable, GMP-compliant cell engineering can effectively mitigate clinical development risks.

7. Using ddPCR Technology To Characterize The Poly(A) Tail Content 7/27/2023

   When characterizing 3’ poly(A) tail length and integrity, Droplet Digital PCR technology demonstrates an orthogonal or alternative method to help ensure the quality and consistency of mRNA products.

8. Addressing Some Of The Most Common Surface Plasmon Resonance Questions 2/18/2022

   This video series addresses some of the most common SPR questions around evaporation, kinetics, sensitivity, and more.

9. Streamline Your mRNA Purification Steps 3/4/2025

   Ensure your mRNA's stability and effectiveness post-transcription with advanced filtration and chromatography techniques to enhance purity and recovery, which delivers high-quality mRNA for superior therapeutics and vaccines.

10. Validation Of An LCMS Hybrid Assay With EVOSEP Cleanup 2/17/2025

    By leveraging this innovative combination, the assay achieves detection limits comparable to traditional methodologies while enhancing overall efficiency and reliability.