Translational Research

1. Using ddPCR Technology To Characterize The Poly(A) Tail Content 7/27/2023

   When characterizing 3’ poly(A) tail length and integrity, Droplet Digital PCR technology demonstrates an orthogonal or alternative method to help ensure the quality and consistency of mRNA products.

2. GLP And The Impact To Start Up Companies 4/18/2022

   Good Laboratory Practice is often used in laboratories and is necessary for specific investigations. What does it mean? And how can it help start-up companies? Watch this video to learn more.

3. Can You Run Crude Samples Using An SPR Instrument? 2/17/2022

   We explore a common misconception and provide examples of complex material being used in an SPR system.

4. Analytics & Assays: Defining mRNA Therapeutic Impurities Early & Often 12/5/2023

   mRNA therapeutics present a whole new safety paradigm not seen in vaccine applications. In this segment, Combined Therapeutics CSO Thomas Van Cott, Ph.D. and Omega Therapeutics Executive Director, Process Development and Analytical Sciences Jeff Atkinson, Ph.D. address the nuances of mRNA therapeutic analytics and assays.

5. Is Evaporation Important For Optical Biosensors? 2/17/2022

   If your sample is open to evaporation effects causing your concentration to change, will your data, and potentially your conclusions, be unreliable?

6. Ori Spotlight: Building Early-Phase CGT Infrastructure For Translational Success 8/27/2025

   Tighter integration between research, process development, and manufacturing is key to accelerating the translation of cell therapies from the lab to the clinic. Learn how a leading academic center is doing it.

7. Addressing Some Of The Most Common Surface Plasmon Resonance Questions 2/18/2022

   This video series addresses some of the most common SPR questions around evaporation, kinetics, sensitivity, and more.

8. How To Best Optimize mRNA Production Workflows 4/11/2023

   Multiple steps in the mRNA manufacturing process can appear more complex than they have to be. Learn how to simplify your approach and produce the best possible mRNA vaccines and therapeutics.

9. Antisense Oligonucleotide Extraction Optimization Reveals Differences 2/17/2025

   Our findings provide critical insights into refining ASO extraction protocols, which can enhance the accuracy of downstream analyses and support further research into ASO-based therapeutics.

10. Validation Of An LCMS Hybrid Assay With EVOSEP Cleanup 2/17/2025

    By leveraging this innovative combination, the assay achieves detection limits comparable to traditional methodologies while enhancing overall efficiency and reliability.