Repligen Process Analytics

  1. Instant PAT Implementation Across Cell Lines, Media, And Scales 7/26/2024

    Explore how MAVERICK’s Raman-based technology delivers instant, reliable measurements of glucose, lactate, and biomass across diverse cell lines, media, and scales.

  2. Real-Time Monitoring Of Key Bioprocess Parameters 5/22/2024

    The success of this experiment shows how the integration of Process Analytical Technology probes into bioreactors can enhance process understanding and enable precise bioprocess monitoring and control.

  3. Continuous Monitoring And Control Of Glucose And Lactate 5/22/2024

    This experiment demonstrates that continuous real-time monitoring of glucose and lactate and dynamic glucose feed control to a low-level set-point leads to improved process and product parameters.

  4. Analyzing Critical Quality Attributes Of Monoclonal Antibodies 5/22/2024

    Use microchip CE-MS technology to achieve quicker peptide mapping analysis, high sample reproducibility, and low artificially induced modifications.

  5. In-line, Raman-Based PAT Solution For Monitoring And Control 5/22/2024

    With an in-line, Raman-based PAT solution you can monitor and control several critical process parameters (CPP) to maintain optimal cell culture conditions.

  6. Comparison To And Advantages Over Traditional Chemometrics Models 4/5/2024

    As Raman spectroscopy, with partial least squares (PLS) models, becomes more popular in bioprocesses applications it's important to recognize the challenges this approach presents.

  7. Analyzing Serum-Free Media For Cell Therapy Applications 3/14/2024

    Identifying critical factors and their concentrations with an eye towards designing an ideally formulated, defined serum-free medium should be carried out using rational and systematic approaches.

  8. Spent Media Analysis To Improve Cell Therapy Manufacturing 3/14/2024

    Targeted metabolomics-based PAT allows for metabolic profiling of the T-cells throughout the cell therapy manufacturing process through spent media analysis.

  9. Metabolite Analysis In Cell Therapy Development 3/14/2024

    Understand the importance of metabolic analysis in cell therapy, optimizing cell culture media formulations, and enhancing the effectiveness of CAR-T cell therapy and stem cell transplantation.

  10. Enabling Real-Time Process Control 10/3/2023

    Defined control strategies enable more intensified and stable cell culture processes such as perfusion which may see dramatically improved productivity.