Spent Media Analysis To Improve Cell Therapy Manufacturing

Explore the use of targeted metabolomics-based process analytical technology (PAT) using the REBEL analyzer for metabolic profiling of T-cells during the manufacturing process. The REBEL analyzer allows for frequent, at-line measurements from bioreactors, enabling real-time monitoring of critical quality attributes (CQAs) to ensure product quality and consistency. Learn more about the challenges involved in scaling out and scaling up production for cellular therapies. As part of your scaling-up process, you may consider outsourcing manufacturing to contract organizations. This can increase production capacity, but can also create bottlenecks and delays. Therefore, it is recommended to keep some aspects of manufacturing in-house to build process knowledge and understanding. The REBEL analyzer is a valuable tool that can be used throughout the cell therapy production process to improve efficiency and accelerate the delivery of therapies to patients. By providing real-time monitoring of CQAs, it ensures product quality and consistency.