Featured Articles

31. Upstream Manufacturing: Is An Open Or Closed System Better? 2/1/2023

    Explore some factors to consider when making the critical decision on whether to use an open or closed system for the bioprocess manufacturing process.

32. Extracellular Vesicle Production, Characterization, And Quantification Methods 12/21/2022

    While extracellular vesicles represent significant opportunity for the biologics space, researchers are still building a foundation of knowledge surrounding their biology, application, and ultimate value.

33. Using A Fixed Bed Reactor System For Expansion Of Human Embryonic Stem Cells 10/18/2022

    Regenerative medicine company ViaCyte Inc. explored new technologies to enable expanded scales of culturing hESCs for development of cell replacement therapies as a functional cure for Type 1 diabetes.

34. How Collaborative R&D Revolutionized Adherent Culture Scale-Up 10/13/2022

    This FBR system is designed to ease or eliminate therapy developers’ difficult choice between adherent and suspension cell culture platforms when scaling production.

35. Gene Therapies: From Research To Reality 9/27/2022

    Partnership scrutiny is critical for cell and gene sponsors transitioning from pure R&D and early preclinical work into clinical-phase development.

36. Helping MEARY Center Paris Advance Personalized Medicine 8/25/2022

    Learn what solutions Paris University Hospitals Consortium’s core facility for cell and gene therapy is using to isolate and expand mesenchymal stromal cells.

37. An Easy-To-Use Bioprinter For 3D Cell Culture 8/17/2022

    Read how culture dispensed by a bioprinter are suitable for further molecular and protein analysis as well as downstream applications including high throughput drug screening.

38. Mechanical Movement EVokes Increase In Extracellular Vesicle Production 8/17/2022

    We demonstrate a 12-layer cell culture vessel can be used to produce seven trillion high quality EVs from mesenchymal stem cells (MSCs).

39. A Novel Approach To Type 1 Diabetes Treatment 8/2/2022

    With the combination of a viral vector platform and a fixed bed bioreactor platform, a lab is working on a curative gene therapy that could address and possibly reverse T1D's underlying mechanisms.

40. From Bench To Billions: Facilitating Scale-Up Of Adherent Cultures For Cell And Gene Therapies 6/27/2022

    We review what researchers should consider when they are creating a risk-mitigating adherent culture process for cell and gene therapy scale-up.