Cell and Gene Manufacturing and Logistics

  1. The Promise Of LLMs In Augmenting Manufacturing 9/24/2026

    Biotech manufacturing holds vast knowledge in unstructured documents that numerical data modeling has never reached. LLMs offer a practical path to finally access it, with the right guardrails in place.

  2. Building Sustainable Biopharma Supply Chains Starts With Procurement 9/24/2026

    Nearly all the industry's emissions happen upstream from core manufacturing functions. This puts sustainability almost entirely on the shoulders of purchasing.

  3. Growing And Scaling A Radiopharmaceuticals Company With AdvanCell's Philina Lee, Ph.D. 9/23/2026

    On this week's episode of the Business of Biotech, Philina Lee, Ph.D., CEO at AdvanCell, explains how lead-based targeted alpha therapies can unlock deeper, more durable cancer responses, and why radiopharmaceutical companies live or die by manufacturing.

  4. Mastering The Path: Devloping Processes For Successful Clinical-Grade mRNA Manufacturing 9/23/2026

    Discover strategies to optimize mRNA manufacturing, improve yield and full-length products, and enable scalable production of mRNA and saRNA therapies.

  5. Behind The Data: Engineering Hepatocyte-Targeted LNPs 9/23/2026

    See how lipid nanoparticle platforms can deliver RNA and large DNA payloads to primary human T cells, improving transfection, expression durability, and CAR insertion efficiency.

  6. Behind The Data: Comprehensive Off-Target Assessment Strategies 9/23/2026

    Explore how biochemical, computational, and cell-based methods can identify, confirm, and interpret off-target editing risks, providing a more complete safety assessment for CRISPR-based therapeutics.

  7. Behind The Data: Iterative Engineering And Optimization Strategies 9/23/2026

    See how iterative optimization across RNA chemistry, lipid nanoparticle formulation, protein engineering, and preclinical testing can improve in vivo liver editing potency and accelerate progression.

  8. Early Planning For CGT Commercialization: Regulatory, Manufacturing, And Market Access 9/23/2026

    Commercialization decisions in cell and gene therapy are made earlier than most manufacturers expect, with regulatory, manufacturing, and market access implications that compound over time.

  9. Why mRNA Delivery Is Shaping The Future Of Genome Editing 9/23/2026

    As genome editing advances clinically, mRNA delivery enables transient expression, scalable manufacturing, and supports next-generation editors and in vivo therapies.

  10. Setting The New Standard For Aseptic Processing: Esco OxAP Isolator 9/22/2026

    Advanced positive-pressure isolators with integrated nebulized decontamination protect sensitive cell processing and aseptic filling operations while ensuring strict cGMP compliance.