Bio-Techne Application Notes

  1. Find The Right T Cell Expansion And Phenotype Balance For Cell Therapy 3/22/2024

    Explore this study that works to determine the optimal concentrations of IL-7 and IL-15 for T cell expansion, as well as how to produce the desired phenotype while requiring less protein.

  2. Touch-Free T Cell Expansion With A Fill-And-Forget Workflow 3/22/2024

    Explore a bioreactor for large-scale, low-cost immune cell therapy manufacturing paired with a "fill-and-forget" workflow and discover how robust T cell expansion can be achieved.

     

  3. Cell Line Development For Biopharmaceutical Production 12/18/2023

    With the right dispenser sorting single cells for clonal growth, you can significantly reduce time and costs, while maintaining quality and sterility in your cell line development processes.

  4. AAV Thermostability Assessment With Micro-Flow Imaging 11/15/2023

    This study demonstrates a micro-flow imaging system's ability to evaluate AAV9 particle purity and stability when subjected to heat stress at two different temperatures: 37°C and 75°C.

  5. Fit-For-Purpose Tool Improving AAV Relative Potency Measurements 8/17/2023

    Help transformative gene therapies reach patients with a fit-for-purpose tool for analytical-grade protein expression quantification in a multi-attribute platform approach.

  6. Characterize Your Viral Vectors From Discovery To GMP Release 8/17/2023

    Simplify your workflow and achieve successful protein analysis with a faster, more robust and highly reproducible alternative method to SDS-PAGE.

  7. Simplify The Qualification Of Your GMP Proteins 4/6/2023

    Discover a streamlined method for characterizing the identity and purity of commonly used GMP cytokines in immune cell therapy manufacturing using an automated capillary electrophoresis instrument.

  8. Enhance Your TIL Expansion 4/6/2023

    Learn how organoids can aid in the evaluation of TIL-tumor cell interactions and facilitate the comparison of expansion media.

  9. Rapid Endonuclease (Benzonase) Quantification 4/6/2023

    Explore a robust and automated assay that is both selective and sensitive, allowing for efficient detection of Benzonase® and Denarase® impurities in bioprocess samples.

  10. A Novel Platform For icIEF Fractionation Of Antibody Charge Variants 1/31/2023

    Learn about an icIEF-based fractionation platform that can be used to collect protein variants and enable downstream analysis of the variants with techniques such as mass spectrometry.