INSIGHTS ON CELL & GENE MANUFACTURING AND LOGISTICS

• Astrea Bioseparations Ligands, Adsorbents, And Chromatography Columns Product Guide

  Astrea Bioseparations has a well-established modular program to support customer projects from small to large scale with ligands, adsorbents, and chromatography columns that design purity into each process.

• Evolve® Process Columns Refresh Kits

  Evolve® Process Column refresh kits provide an economical and convenient alternative to complete replacement of the hardware for single-use applications enabling straightforward renewal of the columns for continued use.

• Evolve® Process Columns

  The Evolve® product range consists of cost effective, ready-to-use process columns providing a high performance, easy to use, low maintenance, scalable technology with excellent flow distribution to support chromatographic processes & biopharmaceutical applications.

• Evolve® Process Columns

  The Evolve® process columns are cost-effective and ready to use. They provide a high performance, easy to use, low maintenance, scalable technology with excellent flow distribution to support chromatographic processes & biopharmaceutical applications.

• Method Migration Of Size-Exclusion And Ion-Exchange Methods For mAb Analysis From HPLC To Modern UHPLC platform

  Although development and quality control laboratories may be slow to replace existing technologies, modern technologies can benefit legacy methods and future development activities as part of lifecycle management.

• Commercializing Advanced Therapy Medicinal Products (ATMPs) Manufacturing Processes

  Improving this one aspect of viral vector manufacturing can help enable scalable production of high-quality vectors with acceptable costs and timelines.

• Zoom On The Importance Of Quality For Viral Vector Manufacturing Optimization

  Industry experts offer advice on the use of GMP raw materials for viral vector manufacturing along with the key points of evolution relating to regulatory guidance and requirements for viral vector production.

• Process Development

  The importance of strategic process development (PD) as a program advances cannot be overstated. It is critical to increasing yields, achieving product quality expectations, and lowering the cost of goods while meeting clinical development milestones.

  The Center for Breakthrough Medicines (CBM) has a PD team with unrivaled experience building and optimizing processes for commercial cell and gene therapies.

• Hydrophobic Interaction Chromatography Screens For Downstream Process Development

  This poster reviews an HIC screening selection kit containing four different ligands - Butyl, Hexyl, Octyl, and Phenyl - to enable end users to screen their process.

• Successfully Filing An IND Using Single Cell Cloning System

  Dr. Andy Tsun, co-founder and VP of Discovery Biology at Biotheus Inc, shares his company's experience using an accelerated workflow for single-cell cloning including how it helped them obtain an IND.