INSIGHTS ON CELL & GENE THERAPY DISCOVERY

• Improving Next-Generation Sequencing Workflows With Droplet Digital PCR

  Optimize NGS workflows by using digital PCR for absolute quantification. Improve library quality, reduce bias, and gain sensitive validation for rare variants in complex genomic samples.

• The Spirit Of MISEV

  MISEV guidelines help extracellular vesicle researchers design robust experiments through transparent reporting and rigorous characterization rather than rigid checklists.

• Galvanizing Large And Small For Clinical Success

  See how two academic investigators accelerated corneal regeneration and lung fibrosis therapies from preclinical research to clinical trials by leveraging scalable GMP solutions and regulatory-ready materials.

• Deference To The Differences Between Fibroblasts And MSCs

  What separates fibroblasts from MSCs when both express identical markers and differentiate into bone, fat, and cartilage? Molecular profiling reveals they exist on a functional spectrum of plasticity.

• Analytical Comparison Of MSC-EV Quality Attributes Across Tissue Sources And Production Platforms

  Explore comprehensive analytics comparing MSC-EV quality attributes across tissue sources, donors, and scalable production platforms to identify critical manufacturing variables.

• Harnessing NanoFlow Cytometry For Quantitative Surface Marker Analysis

  Explore quantitative single-vesicle profiling methods that reveal tissue-specific surface marker expression patterns invisible to bulk EV analysis, with molecular-level resolution across three MSC sources.

• The Complex Journey Of EVs Toward Clinical Translation

  Understand how single-vesicle analysis exposes critical EV heterogeneity, why MSC-EVs face manufacturing hurdles, and what regulators expect from developers pursuing clinical translation.

• How hMSCs Are Helping Power Organ-On-A-Chip Science

  Explore how hMSCs power organ-on-chip systems through multipotency and scalability—from Georgia Tech's bone marrow models to ISS microgravity experiments and precision bioprinting innovations.

• When Is An Exosome Not An Exosome?

  What separates genuine exosomes from microvesicles, apoptotic bodies, or lipoproteins? Explore the markers, assays, and biogenesis pathways that define these particles beyond popular terminology.

• MSCs, Exosomes, And Aging

  Senescent cells spread inflammation and fibrosis across tissues. Learn how MSC-derived exosomes and secreted factors reverse these aging hallmarks by transferring fresh mitochondria and suppressing inflammatory cascades.