INSIGHTS ON CELL & GENE THERAPY DISCOVERY

• mRNA LNPs Drive Safe, Effective Repeat Dosing In Disease Models

  Well-designed lipid nanoparticles enable safe, efficient delivery. OVA-based models show how formulation choices shape efficacy, safety, and anti-tumor outcomes in melanoma research.

• CRISPR Reagents Enable High Efficiencies Of Editing And HDR In iPSCs

  Achieving consistent Homology Directed Repair (HDR) in iPSCs requires optimized CRISPR design and workflows. See how advanced reagents and targeted enhancement strategies improve insertion efficiency.

• CAR Detection Reagents - Applications For Flow Cytometry

  Precise detection of CAR T cells supports reliable analysis and imaging across workflows. See how flexible reagent strategies reduce background, improve specificity, and enable deeper insight.

• Closing The QC Gap For mAbs: Rapid Answers Without Compromising

  Monoclonal antibodies are complex biologics requiring precise analytical strategies to monitor critical quality attributes and impurities, with molecular assays like qPCR supporting sensitive detection, product integrity, and regulatory compliance.

• Designing RNase H1 "Gapmer" Antisense Oligonucleotides

  Effective RNA-targeting oligonucleotide design hinges on balancing affinity, stability, and selectivity. Explore how chemical modifications, sequence choices, and delivery approaches influence potency.

• T Cells In Immunotherapies: The Key Progress Underway

  CAR-T therapies now make up 73% of active pipeline programs, yet solid tumors remain largely out of reach. Where is T cell immunotherapy headed next, and what does it mean for your pipeline strategy?

• Materials Matter: Reframing Raw Material Strategy In Cell And Gene Therapy Development

  Scaling iPSC-based therapies from lab to CGMP manufacturing demands tightly controlled cryopreservation, risk-based QC, and strategic automation to preserve cell viability, consistency, and regulatory readiness.

• Sensitive Viral Safety Testing For Adventitious Virus Detection

  Discover a modern approach to adventitious virus detection that shows how targeted sequencing can achieve sensitive, comprehensive viral safety testing aligned with ICH MAP, RAP, and HAP expectations.

• Direct Cell Lysis Enables Rapid And Robust Vector Copy Number (VCN) Quantification Using QIAcuity Digital PCR

  Explore a faster approach to vector copy number measurement that replaces DNA extraction with direct cell lysis and digital PCR, delivering accurate, reproducible results across fresh and frozen samples.

• Enhanced Lentiviral Vector Characterization Using Digital PCR

  Digital PCR offers a precise, scalable approach to lentiviral vector characterization, enabling reliable genome titer, vector copy number, and RCL detection while reducing variability.