INSIGHTS ON CELL & GENE THERAPY DISCOVERY
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Replacement Of Traditional Adventitious Virus Testing
Explore how molecular-based technologies, including PCR and Next Generation Sequencing, are transforming viral safety testing by offering broader, more effective alternatives to traditional animal-based methods like in vivo assays.
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Small Cell Lung Cancer- Global Clinical Trial Landscape (2025)
Historically dominated by chemotherapy and radiation, the treatment paradigm for small cell lung cancer (SCLC) is evolving in response to limited survival benefits and high relapse rates.
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Understanding RNA Higher-Order Structure Dynamics For CRISPR Applications
Scientists are gaining valuable knowledge about the structural dynamics of guide RNAs used in CRISPR-Cas9. This deeper understanding could pave the way for improved gene editing tools.
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8 Best Practices For Immunogenicity Assay And Companion Diagnostic Development In AAV Gene Therapy
Read more to understand why the partnership between gene therapy companies and diagnostic developers is crucial for advancing the field of gene therapy.
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How Translational Central Lab Services Facilitate Creative Solutions For Biomarker-Driven Studies
Explore the rise of biomarker-driven clinical trials, their benefits, and the complexities involved in their execution to learn about the importance of planning and overcoming challenges in translational studies.
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High-Sensitivity Residual E. coli DNA Testing Supporting Biologics, CGT Development
Advancements in high-sensitivity residual DNA testing enhance the precision of plasmid DNA purity analysis, ensuring compliance with regulatory standards critical for manufacturing processes.
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Selection And Evaluation Of Hybridization Capture Probes For LC/MS Analysis Of Oligonucleotides
To overcome challenges in oligonucleotide LC/MS bioanalysis, consider optimizing probe design by evaluating alternative chemistries like PNA for improved recovery and chromatographic performance.
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Advancing Cytokine, Immune Cell Characterization For Precision Bioanalysis
Unlock deeper insights into immune regulation and accelerate therapeutic discovery by adopting our next-generation inflammatory response assay.
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Expression Analysis Of CTLA-4, PD-1, And PD-L1
Advance personalized immunotherapy in NSCLC by leveraging qPCR-based analysis of CTLA-4, PD-1, and PD-L1 expression to identify predictive biomarkers and guide more effective treatment strategies.
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Optimizing qPCR For Broad-Range Transcript Detection In Anti-PD-1 Therapy
Optimize qPCR protocols for greater sensitivity and reproducibility to accurately measure immune-related gene expression and better identify patients who will benefit from anti-PD-1 immunotherapy.