INSIGHTS ON CELL & GENE THERAPY DISCOVERY

• Fit-For-Purpose Biomarker Development

  Here, we highlight the essential framework of a “fit-for-purpose” biomarker development strategy, emphasizing strategic and transactional engagements with clinical research organizations.

• Biomarkers In Oncology Studies

  Here we provide an overview of oncology biomarker development and strategic considerations.

• LC-MS/MS Method Development Of Endogenous Small Molecule Biomarker

  Biomarkers are essential to improve drug R&D efficiency. Explore some practical solutions for achieving a fit-for-purpose LC-MS/MS biomarker analysis method.

• Exploring Progress In Nanomedicine: Unlocking New Possibilities For Treating Rare Genetic Diseases

  Gene therapy offers hope for rare genetic diseases, with advancements in polymer nanoparticles addressing delivery challenges and paving the way for innovative, effective treatments.

• Structural Characterization Of RNA And Detection Of RNA-Ligand Binding

  Delve into the intricacies of riboswitch behavior and ligand interactions and gain valuable insights into gene regulation and potential therapeutic targets.

• Assigning IR Absorption Bands For RNA Building Blocks Using Microfluidic Modulation Spectroscopy

  Explore the power of MMS in identifying RNA base signatures. This study analyzes vibrational modes of A, G, C, and U, revealing insights into electronic environments and molecular interactions.

• Guidelines And Strategies For The Development, Qualification Of Potency Assay

  Explore key strategies and guidelines to advance the development and qualification of robust potency assays for gene therapy products.

• A Flow Cytometry Toolkit To Measure Expression Of Metabolic Proteins

  Learn about a method that utilizes monoclonal antibodies and flow cytometry to analyze the metabolic state of individual immune cells, advancing immune research and immunotherapy.

• Overview Of Parkinson's Disease: Global Clinical Trials Landscape

  Parkinson's disease affects over 8.5 million globally. Explore how advances in gene therapy, Deep Brain Stimulation, and innovative drugs are transforming treatment and improving patient outcomes.

• Overview Of COVID-19: Global Clinical Trial Landscape

  Explore how COVID-19 has led to significant global morbidity and mortality. Advances in vaccines, therapies, and clinical trials are enhancing disease management and outcomes.