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Media exchange during iPSC differentiation is a key determinant of aggregate health and process consistency. This article explains how tubular bowl centrifugation enables fast, gentle, closed-system media exchange — minimizing cell stress and supporting consistent outcomes in cell-based workflows.
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Translating iPSC therapies from lab to the clinic demands more than just scale — it requires control and repeatability. This case study highlights how replacing manual centrifugation with closed, automated systems ensures consistent recovery, reduced variability, and preserved pluripotency across multiple passages when integrated with Vertical-Wheel® bioreactors.
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Expose the often-overlooked risks in cell washing and pre-formulation that can impact allogeneic therapy quality and yield — from residual contaminants to manual handling variability. Learn how the UniFuge® improves allogeneic therapy manufacturing with integrated buffer exchange, low-shear processing, and closed-system automation — enhancing cell quality and operational efficiency.
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Current cell harvest techniques in allogeneic manufacturing often face significant limitations, including scalability issues and potential cell damage. Learn why a strategic shift in approach to cell harvesting is crucial for achieving high-quality, efficient production at scale.
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Cell washing and media exchange directly impact product quality, yet manual or traditional methods have slow processing times and introduce risk. This article presents data demonstrating how the UniFuge® cell processing platform delivers >98% cell retention and efficient buffer exchange — streamlining processing while maintaining high viability and yield across cell therapy workflows.
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The transition from manual to automated cell processing is vital for therapeutic success. Discover how the UniFuge® platform consolidates harvesting, washing, and media exchange into one closed, automated system — delivering high recovery, reproducibility, and GMP readiness.
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