Navigating The Challenges Of iPSC Differentiation: The Advantages Of Tubular Bowl Centrifuges In Media Exchange

This article discusses the application of tubular bowl centrifuge technology in the cultivation of induced pluripotent stem cells (iPSCs) for regenerative medicine. iPSCs can differentiate into any cell type, making them valuable for disease modeling, drug discovery, and cell therapies. However, their cultivation requires precise control over the cellular environment and efficient media exchange. Traditional methods for this can be laborious, time-consuming, and potentially harmful to the iPSCs. Tubular bowl centrifugation is proposed as a solution, enabling gentle and rapid media exchange in bioreactors, maintaining cell health and functionality, and reducing contamination risk. CARR's technology allows for gentle cell separation in a closed, scalable platform and also offers the PowerFuge and ViaFuge product families for high-g separation and low-shear harvest of viable cells.