From Culture To Cryo: Smarter Cell Washing And Pre-Formulation For Allogeneic Therapies

In allogeneic cell therapy manufacturing, cell washing and pre-formulation mark the final point of control before cells are filled, frozen, and shipped – whether processing iPSCs, MSCs, NK cells, CAR-T cells, or other donor-derived immune cell types. These steps must efficiently remove residual media, preserve viability, and prepare the product for storage or clinical use—without compromising quality or consistency.

Yet many workflows still rely on open systems, manual handling, or separation methods not optimized for sensitive cell types. The result is often variable recovery, inconsistent buffer exchange, and a higher risk of contamination.

Cell washing and pre-formulation aren’t just end-of-line steps—they’re essential to ensuring the integrity of the final product.