Newsletter | January 15, 2026

01.15.26 -- Timing Tech Transfer With Complex Raw Materials

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Simplified Harvest and Media Exchange in Cell Therapy: Consistent, Compliant Scale-Up from Development to GMP

Developing robust cell harvest and media exchange processes has become increasingly complex in GMP manufacturing. Variability from equipment, scale, and automation can delay timelines and impact product quality. In this webinar, CARR Biosystems shares case studies showing how low-shear, single-use centrifugation enables consistent harvest and media exchange across cell types while preserving CQAs. Click here to learn more.

FOCUS ON MANUFACTURING

Timing Tech Transfer With Complex Raw Materials

Tech transfer complexity depends on product maturity, but don't assume a straightforward experience just because you have market approval and a commercial product. In fact, the risk is often greater. When outsourcing drug product manufacturing to scale up for clinical production or expanding capacity for a commercial product, it's best not to guess, Yan Zhi says in this segment of Cell & Gene Live "Viability On The Line."

What Is Transfection?

Gain insight into the process of transfection and why it is crucial for studying gene function and has applications in various fields, including drug development and gene therapy.

Selecting The Right Single-Use Materials In Biopharmaceutical Manufacturing

Manufacturing operations are getting a boost thanks to single-use technologies, but how do biopharmaceutical manufacturers choose the right materials for constructing their single-use solutions?

Cell Culture Media Demystified For Performance, Quality, And Innovation

Cell culture media isn’t one-size-fits-all. Learn how media composition, customization, and analytics can dramatically improve cell growth, productivity, and product quality for complex processes.

CDMO Media And Buffer Outsourcing: A Strategic Advantage

Read how outsourcing cell culture media and buffers removes bottlenecks, freeing specialized CDMO resources. Ensure consistency, accelerate timelines, and streamline GMP readiness for client success.

Scalable Strategies For Intensified Viral Vector Production

Learn a strategy for scalable bioprocessing and media optimization that drives intensified viral vector production. Achieve high cell density, excellent viability, and consistent AAV titers from 50mL to 5L.

Top Five Downstream Processing Challenges For Viral Vectors And Exosomes

From discovery to patient doses, viral vectors and exosomes face a complex journey. Researchers must navigate five key downstream processing challenges to ensure these therapies reach their full potential.

High-Yield Expression Of Complex Proteins From Stable Pools

This study presents the development of apoptosis-resistant CHO cell lines (DKO1 and DKO2), using electroporation technology, with the goal of enhancing biotherapeutic production.

Cytokines For Ex Vivo Cell Culture

Comparable T cell expansion and function between cytokine sources were demonstrated. Generated CAR-T cells showed robust cytotoxicity and lower exhaustion markers.

Efficient FBS Removal And Cell Concentration In Vero Cell Cultures

Achieve consistent Vero cell concentration and maintain high cell viability with minimal loss using this instrument that is showing potential to optimize Vero cell culture processing.

Addressing The Challenges Of LNP Upscaling

Overcome LNP upscaling challenges by leveraging fluid mechanical principles. See how Impingement Jets Mixing achieves reproducible turbulence and consistent LNP quality across all production scales.

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Join Cell & Gene's Chief Editor, Erin Harris, for this timely Cell & Gene Live offering an in-depth regulatory outlook with two of the field's most trusted experts, Wilson Bryan, M.D., former director of FDA's Office of Tissues and Advanced Therapies (OTAT), and Daniela Drago, Ph.D., RAC, Partner at NDA Partners. Learn More!

MANUFACTURING SOLUTIONS

Reduce Batch Failure Risk With An Innovative Platform - Cytiva

Peristaltic Pump System For Aseptic Filling Of Pharmaceuticals - AST

Enhancing Post-EP Proliferation - Femtobiomed Inc.

AAV Edge System - Asimov

Support Growth With Material For Cell Culture - Eppendorf SE

Get Quality Components Delivered Quickly - West Pharmaceutical Services, Inc.

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