Efficient FBS Removal And Cell Concentration In Vero Cell Cultures

Achieve consistent Vero cell concentration and maintaining high cell viability with minimal loss, while also achieving an 89.6% reduction in FBS levels, with CARR Biosystem’s UFMini.

In viral vaccine manufacturing, Vero cells are typically cultured using DMEM-F12, supplemented with 10% FBS. As adherent, anchorage-dependent cells, Vero cells require detachment from the substrate, which is achieved through trypsinization. The CARR Biosystem’s UFMini achieves concentration and FBS removal from Vero cell cultures using PBS as the wash solution. The UFMini’s capability to concentrate and wash Vero cells efficiently while preserving their viability in a closed, automated system underscores its potential for optimizing Vero cell culture processes.