12.21.23 -- Overcoming Limitations Of CAR T-Cell Therapy

With regulatory requirements and GMP recommendations trending toward less human interaction and more robotic automation, robotics is the way of the future for the ATMP industry.

Sterile fill operators play a crucial role in ensuring contaminant-free pharmaceutical products. Explore best practices that help operators through gowning training, mobile cleanroom benefits, and more.

This critical information about the component in your cleanroom will help your organization meet EMS requirements and shortens on-site integration.

Here, we report the development of an application that streamlines LC-MS data acquisition, data intact mass processing, and reporting of results suitable for a compliance-ready environment.

Learn about the multicolor flow cytometry analysis necessary to study natural killer (NK) cell phenotype and the function of isolated NK cells from whole blood.

A growing number of AAV product developers are recognizing the value in moving to suspension as early in development as possible in order to optimize production.

There is a growing shift in CAR T cell therapies and tumor infiltrating lymphocyte (TIL) treatments that is moving away from the use autologous cells, to allogeneic applications instead.

Achieve a more physiologically relevant setting with less reliance on model animals when studying diseases like cancer through the combination of CRISPR screening and bulk spheroid production.

Multi-site manufacturing reduces the risk of supply chain shortages and makes transporting goods faster and more sustainable. Learn more about multi-site manufacturing and security of supply.

A byproduct of several cell therapy groups attempting to reduce processes complexity to make them safer and more cost-efficient is that there's a lack of standardization across the production sector.

Evaluate a peer analysis of how a single cell dispenser helped their research team streamline the development process of single-cell clones for the cell lines they are working with.

If your CGT manufacturing company is transitioning to automation, the strategies and the provided manufacturing road map can improve your efficiencies along the developmental journey.

Analyze the cost distribution over time for autologous CAR-T therapy manufacturing using process economics and additional insights. Discover how cell therapy manufacturers can combat these costs.

Global demand for high-quality recombinant AAV (rAAV) manufacturing is escalating. We discuss the challenges that rAAV experts face and the best practice solutions they have employed to overcome them.

Improve your manufacturing of mAbs and vaccines, your supplier collaboration, and other factors in your processes with these insightful lessons.

Closed single-use systems reduce the risk of two critical forms of contamination: biological contamination and cross-contamination.