Article | August 17, 2023

A Single Cell Dispenser To Accelerate The Development Of CRISPR-Edited Cell Line Models

Source: bio-techne
Embryonic stem cell GettyImages-1154785553

CRISPR has made huge strides for drug discovery with how it's revolutionizing cellular model creation. The introduction of the Namocell Single Cell Dispenser brought significant improvement to workflow ease-of-use, where the cells are prepared and sorted in the same room. Some of the benefits include requiring no maintenance and eliminating the tedious cell preparation of fixing and staining the cells to visualize protein expression and localization.

A huge advantage of this approach is that it enables more physiologically accurate models, allowing drug changes to be studied on the endogenous targets without artificially inducing a cell to produce a recombinant protein that may or may not be expressed in the cells normally. The leader of a team focused on utilizing CRISPR genome editing shares how the Namocell Single Cell Dispenser has proven instrumental in streamlining the development process of single-cell clones for the cell lines he's working with.

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