03.14.24 -- mRNA: Challenges & Opportunities For Scale-Out, Optimization

Implementing integrated solutions can provide cell and gene therapy manufacturing systems that work in concert to create a closed, automated, scalable, and performance-qualified network of unit operations.

Discover the key to a successful quality transformation, explore the business value of modern quality systems, and learn how quality leaders can build a compelling case for change.

Navigating the complex landscape of clinical trials can be challenging. Utilize this reliable CRO Checklist to empower teams to stay ahead and safeguard every trial's budget effectively.

Single-use tubular bowl centrifuges are standing out to cell therapy developers for their ability enable the optimal balance between high separation efficiency, high productivity, and low shear.

Review an in-depth study of the automation of a mammalian cell-line development workflow — the automated, integrated screening of transfected cells for edits, monoclonality, and growth assessment.

See how clonal imaging technology combined with a trained neural network can identify single cells reliably, demonstrating process accuracy and shortening development timelines.

Learn how to set up a small-scale CAR T cell research workflow to simplify the transition to large-scale manufacturing in preclinical development, and why using suitable tools early on is key.

Review data and evidence that demonstrates the benefits of an integrated approach to achieving critical end-user goals such as scalability, efficiency, sustainability, and optimized process economics.

This study establishes basic cell culture parameters for expansion of DF-1 cells in the Corning CellCube System — a compact and scalable method for mass culture of attachment-dependent cells.

Characterize the identity and purity of commonly used GMP cytokines in immune cell therapy manufacturing using an automated capillary electrophoresis instrument that's fast and easy to use.

Consider this approach to method development, where more than one AAV critical quality attribute can be measured within a single analytical run, reducing the amount of test material required.

Explore the offerings of a powerful batch solution that dramatically increases operator productivity and enables distributed batch control for a smarter approach to unit operations.