Automation Of The CRISPR- Based Cell Line Development Workflow
Source: Danaher Life Sciences

Typical cell-line development requires the screening of tens of thousands of clones to find the best stable cells that yield high amounts of bioproducts. Review an in-depth study of the automation of a mammalian cell-line development workflow—the automated, integrated screening of transfected cells for edits, monoclonality, and growth assessment. The integrated system used includes a single-cell printer, Clone Select Imager – Florescence (CSI-FL), a liquid handler, an automated incubator, hotels, barcode readers, and a collaborative robot.
Benefits of the system include:
- Quick scale-up acceleration
- Increase in walk-away time
- Consistent processing
- Reduce redundant tasks
- Better cellular monitoring
- Dynamic workflow solutions
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Danaher Life Sciences
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