Newsletter | May 7, 2026

05.07.26 -- Lilly's Unified Mindset For A Global Parenteral And Device Manufacturing Network

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At TIDES USA 2026, experts discuss how formulation science, stability strategies, and advanced analytics help reduce CMC risk and enable confident development of peptide and nucleic acid therapeutics.

FOCUS ON MANUFACTURING

Lilly's Unified Mindset For A Global Parenteral And Device Manufacturing Network

Eli Lilly and Company's one-team mindset aims to templatize facility design while remaining nimble enough to react to new manufacturing breakthroughs. Gain insight into the strategy in this Q&A.

Current Challenges In The Plasmid DNA Manufacturing Process

PolyA tail stability shapes mRNA potency, consistency, and manufacturability. Addressing integrity early reduces variability, simplifies workflows, and supports reliable clinical scale‑out.

The Advantages Of Tubular Bowl Centrifuges In Media Exchange

Explore how tubular bowl centrifuges improve media exchange during induced pluripotent stem cell cultivation. This application supports more efficient workflows for regenerative medicine scale-up.

The Proven, Practical Gateway To Upstream Process Intensification

N-1 perfusion enables higher inoculum densities, faster production, and reduced costs without altering fed-batch processes. Uncover this practical path to intensification for biologics manufacturers.

Next-Generation Cell Therapy: Eliminating Thermal Shock In Electroporation

Conventional electroporation methods struggle with damaging heat buildup. Discover how innovative flow technology leverages physics to protect cells and enable large-scale therapeutic production.

Comparing Control Strategies For Scalable Viral Vector TFF Operations

Analyze how TMP and permeate control strategies impact flux and impurity removal during viral vector processing. Understanding these variables ensures more predictable scale-up across development.

Overview Of Leveraging Digital Twins To Optimize Aseptic Fill-Finish Productivity

Digital twin technology optimizes aseptic fill-finish through real-time mirroring and predictive simulation. Improve yields and validate complex recipes by integrating dynamic virtual models.

Enhanced T Cell Expansion While Maintaining Early Memory Cell Phenotype

Study the development and performance of this animal origin-free (AOF) T cell culture medium designed for T cell expansion through an experiment comparing it to other AOF or xeno-free basal offerings.

The Need For Consistency In Leukopak Collection, Minimize Raw Material Variation

From donor variability to collection site inconsistencies, cell and gene therapy faces raw material challenges. Ensuring stable, high-quality leukopaks is vital for effective treatments.

Background-Free Analysis Of Mouse TILs

Syngeneic mouse tumor models are crucial for immunotherapy research, but variability in TILs and nonspecific binding complicate analysis. See how blocking reagents help but make the process more labor-intensive.

MANUFACTURING SOLUTIONS

Seamless Scale-Up With The First And Only GMP Transfection Stabilizer - Mirus Bio

A Compact, Flexible, And Easy To Use Benchtop Mixer - Cytiva

Syringe System For Pediatric Blood And Plasma Transfusion - Charter Medical

Quantifying Potency In Cell & Gene Therapy - LICORbio

Scale-Up In Single-Use Bioreactors From R&D To Commercial Manufacture - Eppendorf SE

Xeno-Free (XF) Human Dermal Fibroblasts - RoosterBio

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