11.20.25 -- How AI And ML Drive iPSC Quality

Explore a scalable protocol for T cell activation and expansion, designed to enhance immunotherapy workflows. This approach ensures robust T cell growth, viability, and memory phenotypes for clinical applications. 

Cross-functional teams coordinate and optimize cell therapy manufacturing and release for Phase 1 trials by aligning multiple operational activities, supporting patient timelines, and upholding the safety and quality.

Learn about the key workflow steps for Sf9 cell expansion, virus preparation, and protein production in stirred-tank bioreactors, including methods for monitoring GFP expression.

This study demonstrates the automated magnetic isolation of CD4/CD8+ cells from fresh or frozen leukapheresis using a functionally closed cell processing system paired with a modular application.

Discover how AI can optimize processes, improve efficiency, and enhance the understanding of cellular processes, ultimately leading to more effective and personalized patient treatments.

Optimize your lab's workflow by understanding the trade-offs between rapid enzymatic isolation and the superior cell integrity of explant culture for mesenchymal stem cells.

Assimilate how effective cell banking and scale-up strategies can reduce risk and cost in advanced therapy manufacturing. Learn practical ways to meet increasing cell and exosome quantity needs.

Delve into learning about a collaboration that has yielded advanced modular cleanrooms, integrating cutting-edge building automation, critical monitoring, and data aggregation for manufacturing intelligence.

See how innovative bioreactor technology enables consistent and efficient scale-up of human induced pluripotent stem cells (hiPSCs) from 100ml to 3L, ensuring optimal cell yield and quality.

With a helpful assessment and the right process liquid preparation services, the CDMO featured in this study was able to find a path toward meeting the surge in demand for a client's therapeutic .

This experiment demonstrates that continuous real-time monitoring of glucose and lactate and dynamic glucose feed control to a low-level set-point leads to improved process and product parameters.