Newsletter | May 24, 2023

05.24.23 -- Get Up To Speed In Your UF/DF


Tangential Flow Filtration (UF/DF) Of Plasmid DNA

Due to their structure, plasmids can pass through pores smaller than their apparent molecular weight. DNA can be shear-sensitive and tends to increase with plasmid size, which can result in degradation and reduction of overall yield. Learn how optimization of hydraulic parameters can help you achieve the desired plasmid purity, formulation, and concentration specifications.

Ultrafiltration/Diafiltration (UF/DF) Of Adeno-Associated Viruses (AAV)

In downstream manufacturing of AAV, tangential flow filtration (TFF) is an essential operation. Here, we evaluate the scalability performance of Pellicon® Capsule, a first-of-its-kind spiral-wound TFF device, and Pellicon® XL 50 cassette.

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Achieve Linear Scalability With Capsules For Gene Therapy And Vaccines

Ideal for single-use ultrafiltration and diafiltration of viral gene therapy and vaccine products, Pellicon® Capsules are first-of-their-kind spiral-wound TFF filters that offer consistent performance and linear scalability at any manufacturing stage.

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Innovative Single-Use Tangential Flow Filtration (TFF) Devices

Discover innovative single-use tangential flow filtration (TFF) devices for streamlined bioprocessing. Pellicon® Capsules with Ultracel® membrane are the ideal TFF devices for the filtration of solutions that require single-use capabilities.

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