Newsletter | September 4, 2024

09.04.24 -- Advancing PSC-Based Therapies: The Application Of Non-Integrating Engineering Strategies

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FOCUS ON TRANSLATIONAL RESEARCH

Advancing PSC-Based Therapies: The Application Of Non-Integrating Engineering Strategies To Improve Directed Differentiation

By Dr. Erin Kimbrel, Ph.D., President Research, Astellas Institute for Regenerative Medicine, Astellas Pharma Inc.

This article explains why the incorporation of non-integrating, traceless engineering tools in PSC directed differentiation approaches could significantly help streamline the development of allogeneic cell therapies.

Considerations For Cell Therapy Development And Manufacturing

e-book | Applied Biosystems by Thermo Fisher Scientific, qPCR

Review the latest methodologies, common practices, resources, applications and more to support every step of your cell therapy manufacturing workflow.

Generation Of Stable CHO Cell Lines For Protein Production

White Paper | Mirus Bio

By following the five steps of a specialized protocol, exceptional yields and stable cell lines can be achieved in CHO cells using antibiotic selection.

An Overview Of RNA Delivery: Challenges And Innovation

Article | By Claire Gueguen Ph.D., Malik Hellal Ph.D., Maria Nicla Loviglio Ph.D., et al., Polyplus

While lipid-based solutions have been utilized in approved products, ongoing issues remain regarding their specificity and stability, which continue to be a key area of research.

Producing Therapeutic Cardiomyocytes From iPSC Stem Cells

Webinar | Sartorius

Experts from Albumedix and Heartseed show how they navigated challenges on the path to commercialization and successfully advanced a promising cardiomyocyte therapy to clinical trials.

Democratizing Organ-On-A-Chip Technology

Webinar | Emulate

Learn about drug development challenges, the evolution of in vitro cell culture towards greater human relevance, a complete solution for creating human-relevant and translatable models, and more.

Efficient FBS Removal And Cell Concentration In Vero Cell Cultures

Application Note | CARR Biosystems

Benefit an instrument that is showing potential to optimize Vero cell culture processes through concentration and FBS removal using PBS as the wash solution.

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The supply chain for mRNA-based cell and gene therapies presents unique challenges due to the sensitive nature of these products. Join Cell & Gene Live on September 24th for a digital discussion on how the industry can improve the efficiency, reliability, and scalability of the supply chain for mRNA-based therapies. Registration is free thanks to the support of Roche CustomBiotech.

TRANSLATIONAL RESEARCH SOLUTIONS

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Virus Purification Resin Selection Card - Bio-Rad Laboratories, Inc.

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