Newsletter | April 15, 2025

04.15.25 -- 4 Key Solid Tumor Therapy Objectives iPSCs Can Help Achieve

SPONSOR

Webinar: Inside the Development of an AAV8 Production Platform Designed for Scale

Adeno-associated virus (AAV) vectors are pivotal in gene therapy, yet their production faces significant challenges, including scalability, low recovery rates, and the need for effective separation of empty and full capsids. This webinar presents a comprehensive AAV8 production platform developed together with CDMO Matica Biotechnology, and addresses industry pain points through innovative upstream and downstream processes. Click here to register.

FOCUS ON MANUFACTURING

4 Key Solid Tumor Therapy Objectives iPSCs Can Help Achieve

Induced pluripotent stem cells offer some key biologic, technical, and financial advantages over more established PBMC-derived therapies.

Scaling Up An Upstream Process For Gene Therapies

It's important to evaluate your starting point when scaling an upstream process. Review key considerations for deciding between adherent and suspension cells.

A Cost-Effective Alternative To Traditional Protein A Resin Chromatography

Learn more about this cost-effective, efficient alternative to traditional Protein A resin chromatography for mAb production, enhancing productivity and reducing costs.

Cracking The Reproducibility Code: Sera Is A Key Component

Struggling with reproducible cell culture results? Sera variability is a major culprit. Learn how to choose the right sera, test lots, and stock up to ensure consistency and boost reproducibility.

Perfusion Technology For Virus Manufacturing Process Intensification

Perfusion cell culture technology supports high cell densities and product yields for viral vaccine manufacturing, offering a reliable way to produce high-quality cells at a commercial scale.

Physiologix Serum Replacement Performance On T Cells

A serum replacement for promoting T cell growth and functionality in cell therapy development shows comparable or superior performance to traditional human serum supplements.

Single-Use Assembly Capabilities To Keep Pace With Biopharma Dynamics

Discover how a vendor-independent partner assists global life science companies and CDMOs with innovative single-use technologies to mitigate risks and ensure uninterrupted manufacturing.

Demonstrating Analytical Comparability In Analytical Development

Explore an overview of how mass photometry works and the effort being put in to establish an analytical workflow for gene therapy products.

Single-Use Solutions For Research And Process Development

Can supply chain assurance be maintained while offering an array of possibilities to achieve complex process designs?

SPONSOR

Webinar: Future-Proofing the Material Transfer Process in Your Facility with Automated Bio-decontamination

Developers of cell and gene therapies face challenges in safely transferring living materials into closed systems without contamination or damage. A robust material transfer program requires risk assessment and modern approaches, combining manual disinfection with automated bio-decontamination. This webinar explores how automated bio-decontamination systems can enhance material transfer processes, ensuring patient safety and regulatory compliance. Click here to learn more.

MANUFACTURING SOLUTIONS

Vertical-Wheel Bioreactor Product Guide - PBS Biotech, Inc.

A Revolutionary Single-Use Rocking Bioreactor System - Cytiva

Oligonucleotide Synthesis Solutions - KNAUER

Automated Batch And/Or Continuous Centrifuge For Low Shear Separation - CARR Biosystems

Welders And Sealers That Deliver Dependable, Sterile Results - Terumo BCT

Cryovial Filling Platform: cryoFIL - 3P Innovation

Accelerating Gene Therapy With The HIT SCAN Platform - Battelle

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